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Items: 1 to 20 of 208

1.

Defining the consequences of genetic variation on a proteome-wide scale.

Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP.

Nature. 2016 Jun 15;534(7608):500-5. doi: 10.1038/nature18270.

PMID:
27309819
2.

Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness.

Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipilä P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S.

Nat Med. 2016 Jul;22(7):771-9. doi: 10.1038/nm.4115. Epub 2016 Jun 6.

PMID:
27270587
3.

Eric Lander and David Botstein on Mapping Quantitative Traits.

Churchill GA.

Genetics. 2016 May;203(1):1-3. doi: 10.1534/genetics.116.189803. Epub 2016 May 5. No abstract available.

PMID:
27183560
4.

R2d2 Drives Selfish Sweeps in the House Mouse.

Didion JP, Morgan AP, Yadgary L, Bell TA, McMullan RC, Ortiz de Solorzano L, Britton-Davidian J, Bult CJ, Campbell KJ, Castiglia R, Ching YH, Chunco AJ, Crowley JJ, Chesler EJ, Förster DW, French JE, Gabriel SI, Gatti DM, Garland T Jr, Giagia-Athanasopoulou EB, Giménez MD, Grize SA, Gündüz İ, Holmes A, Hauffe HC, Herman JS, Holt JM, Hua K, Jolley WJ, Lindholm AK, López-Fuster MJ, Mitsainas G, da Luz Mathias M, McMillan L, Ramalhinho Mda G, Rehermann B, Rosshart SP, Searle JB, Shiao MS, Solano E, Svenson KL, Thomas-Laemont P, Threadgill DW, Ventura J, Weinstock GM, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

Mol Biol Evol. 2016 Jun;33(6):1381-95. doi: 10.1093/molbev/msw036. Epub 2016 Feb 15.

5.

Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross.

Tyler AL, Donahue LR, Churchill GA, Carter GW.

PLoS Genet. 2016 Feb 1;12(2):e1005805. doi: 10.1371/journal.pgen.1005805. eCollection 2016 Feb.

6.

The Mouse Universal Genotyping Array: From Substrains to Subspecies.

Morgan AP, Fu CP, Kao CY, Welsh CE, Didion JP, Yadgary L, Hyacinth L, Ferris MT, Bell TA, Miller DR, Giusti-Rodriguez P, Nonneman RJ, Cook KD, Whitmire JK, Gralinski LE, Keller M, Attie AD, Churchill GA, Petkov P, Sullivan PF, Brennan JR, McMillan L, Pardo-Manuel de Villena F.

G3 (Bethesda). 2015 Dec 18;6(2):263-79. doi: 10.1534/g3.115.022087.

7.

Genetic Architectures of Quantitative Variation in RNA Editing Pathways.

Gu T, Gatti DM, Srivastava A, Snyder EM, Raghupathy N, Simecek P, Svenson KL, Dotu I, Chuang JH, Keller MP, Attie AD, Braun RE, Churchill GA.

Genetics. 2016 Feb;202(2):787-98. doi: 10.1534/genetics.115.179481. Epub 2015 Nov 27.

PMID:
26614740
8.

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.

Gralinski LE, Ferris MT, Aylor DL, Whitmore AC, Green R, Frieman MB, Deming D, Menachery VD, Miller DR, Buus RJ, Bell TA, Churchill GA, Threadgill DW, Katze MG, McMillan L, Valdar W, Heise MT, Pardo-Manuel de Villena F, Baric RS.

PLoS Genet. 2015 Oct 9;11(10):e1005504. doi: 10.1371/journal.pgen.1005504. eCollection 2015 Oct.

9.

Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays.

Dell'Acqua M, Gatti DM, Pea G, Cattonaro F, Coppens F, Magris G, Hlaing AL, Aung HH, Nelissen H, Baute J, Frascaroli E, Churchill GA, Inzé D, Morgante M, Pè ME.

Genome Biol. 2015 Sep 11;16:167. doi: 10.1186/s13059-015-0716-z.

10.

Identification of microRNAs associated with allergic airway disease using a genetically diverse mouse population.

Rutledge H, Baran-Gale J, de Villena FP, Chesler EJ, Churchill GA, Sethupathy P, Kelada SN.

BMC Genomics. 2015 Aug 25;16:633. doi: 10.1186/s12864-015-1732-9.

11.

Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database.

Bogue MA, Churchill GA, Chesler EJ.

Mamm Genome. 2015 Oct;26(9-10):511-20. doi: 10.1007/s00335-015-9595-6. Epub 2015 Aug 19.

12.

High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping.

Rau CD, Parks B, Wang Y, Eskin E, Simecek P, Churchill GA, Lusis AJ.

G3 (Bethesda). 2015 Jul 28;5(10):2021-6. doi: 10.1534/g3.115.020784.

13.

Aging Research Using Mouse Models.

Ackert-Bicknell CL, Anderson LC, Sheehan S, Hill WG, Chang B, Churchill GA, Chesler EJ, Korstanje R, Peters LL.

Curr Protoc Mouse Biol. 2015 Jun 1;5(2):95-133. doi: 10.1002/9780470942390.mo140195.

14.

Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice.

Simecek P, Churchill GA, Yang H, Rowe LB, Herberg L, Serreze DV, Leiter EH.

G3 (Bethesda). 2015 Mar 3;5(5):771-5. doi: 10.1534/g3.115.017046.

15.

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, Geiger TR, Gooch TJ, Garland T Jr, Harrill AH, Hunter K, McMillan L, Holt M, Miller DR, O'Brien DA, Paigen K, Pan W, Rowe LB, Shaw GD, Simecek P, Sullivan PF, Svenson KL, Weinstock GM, Threadgill DW, Pomp D, Churchill GA, Pardo-Manuel de Villena F.

PLoS Genet. 2015 Feb 13;11(2):e1004850. doi: 10.1371/journal.pgen.1004850. eCollection 2015 Feb.

16.

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.

Bogue MA, Peters LL, Paigen B, Korstanje R, Yuan R, Ackert-Bicknell C, Grubb SC, Churchill GA, Chesler EJ.

J Gerontol A Biol Sci Med Sci. 2016 Feb;71(2):170-7. doi: 10.1093/gerona/glu223. Epub 2014 Dec 22.

17.

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice.

Church RJ, Gatti DM, Urban TJ, Long N, Yang X, Shi Q, Eaddy JS, Mosedale M, Ballard S, Churchill GA, Navarro V, Watkins PB, Threadgill DW, Harrill AH.

Food Chem Toxicol. 2015 Feb;76:19-26. doi: 10.1016/j.fct.2014.11.008. Epub 2014 Nov 28.

18.

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity.

French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA.

Environ Health Perspect. 2015 Mar;123(3):237-45. doi: 10.1289/ehp.1408202. Epub 2014 Nov 6.

19.

When are results too good to be true?

Churchill GA.

Genetics. 2014 Oct;198(2):447-8. doi: 10.1534/genetics.114.169912. No abstract available.

20.

Quantitative trait locus mapping methods for diversity outbred mice.

Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, Chesler EJ, Broman KW, Churchill GA.

G3 (Bethesda). 2014 Sep 18;4(9):1623-33. doi: 10.1534/g3.114.013748.

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