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Items: 1 to 20 of 320

1.

The sea urchin mitochondrial transcription factor A binds and bends DNA efficiently despite its unusually short C-terminal tail.

Malarkey CS, Lionetti C, Deceglie S, Roberti M, Churchill ME, Cantatore P, Polosa PL.

Mitochondrion. 2016 Apr 14. pii: S1567-7249(16)30023-X. doi: 10.1016/j.mito.2016.04.004. [Epub ahead of print]

2.

Strategies to target HIV-1 in the central nervous system.

Gray LR, Brew BJ, Churchill MJ.

Curr Opin HIV AIDS. 2016 Mar 2. [Epub ahead of print]

PMID:
26945147
3.

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation.

Horita H, Wysoczynski CL, Walker LA, Moulton KS, Li M, Ostriker A, Tucker R, McKinsey TA, Churchill ME, Nemenoff RA, Weiser-Evans MC.

Nat Commun. 2016 Mar 4;7:10830. doi: 10.1038/ncomms10830.

PMID:
26940659
4.

Lipidomic dataset of plasma from patients infected with wild type and nef-deficient HIV-1 strain.

Meikle P, Low H, Churchill MJ, Bukrinsky M, Sviridov D.

Data Brief. 2015 Dec 11;6:168-75. doi: 10.1016/j.dib.2015.11.067. eCollection 2016 Mar.

5.

Toxicity and in vitro activity of HIV-1 latency-reversing agents in primary CNS cells.

Gray LR, On H, Roberts E, Lu HK, Moso MA, Raison JA, Papaioannou C, Cheng WJ, Ellett AM, Jacobson JC, Purcell DF, Wesselingh SL, Gorry PR, Lewin SR, Churchill MJ.

J Neurovirol. 2016 Jan 4. [Epub ahead of print]

PMID:
26727904
6.

Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.

Tamburrino A, Churchill MJ, Wan OW, Colino-Sanguino Y, Ippolito R, Bergstrand S, Wolf DA, Herz NJ, Sconce MD, Björklund A, Meshul CK, Decressac M.

Acta Neuropathol Commun. 2015 Dec 14;3(1):84. doi: 10.1186/s40478-015-0263-6.

7.

HIV reservoirs: what, where and how to target them.

Churchill MJ, Deeks SG, Margolis DM, Siliciano RF, Swanstrom R.

Nat Rev Microbiol. 2016 Jan;14(1):55-60. doi: 10.1038/nrmicro.2015.5. Epub 2015 Nov 30.

PMID:
26616417
8.

Lipid metabolism in patients infected with Nef-deficient HIV-1 strain.

Low H, Cheng L, Di Yacovo MS, Churchill MJ, Meikle P, Bukrinsky M, Hill AF, Sviridov D.

Atherosclerosis. 2016 Jan;244:22-8. doi: 10.1016/j.atherosclerosis.2015.10.103. Epub 2015 Oct 30.

PMID:
26581048
9.

The evolution of aquatic feeding in seals: insights from Enaliarctos (Carnivora: Pinnipedimorpha), the oldest known seal.

Churchill M, Clementz MT.

J Evol Biol. 2016 Feb;29(2):319-34. doi: 10.1111/jeb.12783. Epub 2015 Nov 24.

PMID:
26538168
10.

Efficacy and safety of subcutaneous golimumab in methotrexate-naïve patients with rheumatoid arthritis: 5-year results of the GO-BEFORE trial.

Emery P, Fleischmann RM, Strusberg I, Durez P, Nash P, Amante E, Churchill M, Park W, Pons-Estel B, Han C, Gathany TA, Xu S, Zhou Y, Leu JH, Hsia EC.

Arthritis Care Res (Hoboken). 2015 Oct 16. doi: 10.1002/acr.22759. [Epub ahead of print]

PMID:
26474452
11.

IL-17 producing mast cells promote the expansion of myeloid-derived suppressor cells in a mouse allergy model of colorectal cancer.

Chen X, Churchill MJ, Nagar KK, Tailor YH, Chu T, Rush BS, Jiang Z, Wang EB, Renz BW, Wang H, Fung MC, Worthley DL, Mukherjee S, Wang TC.

Oncotarget. 2015 Oct 20;6(32):32966-79. doi: 10.18632/oncotarget.5435.

12.

Molecular Gymnastics: Mechanisms of HIV-1 Resistance to CCR5 Antagonists and Impact on Virus Phenotypes.

Roche M, Borm K, Flynn JK, Lewin SR, Churchill MJ, Gorry PR.

Curr Top Med Chem. 2016;16(10):1091-106.

PMID:
26324043
13.

A Randomized Trial Comparing Disease Activity Measures for the Assessment and Prediction of Response in Rheumatoid Arthritis Patients Initiating Certolizumab Pegol.

Curtis JR, Churchill M, Kivitz A, Samad A, Gauer L, Gervitz L, Koetse W, Melin J, Yazici Y.

Arthritis Rheumatol. 2015 Dec;67(12):3104-12. doi: 10.1002/art.39322.

PMID:
26316013
14.

CNS-specific regulatory elements in brain-derived HIV-1 strains affect responses to latency-reversing agents with implications for cure strategies.

Gray LR, Cowley D, Welsh C, Lu HK, Brew BJ, Lewin SR, Wesselingh SL, Gorry PR, Churchill MJ.

Mol Psychiatry. 2016 Apr;21(4):574-84. doi: 10.1038/mp.2015.111. Epub 2015 Aug 25.

15.

Two high-mobility group box domains act together to underwind and kink DNA.

Sánchez-Giraldo R, Acosta-Reyes FJ, Malarkey CS, Saperas N, Churchill ME, Campos JL.

Acta Crystallogr D Biol Crystallogr. 2015 Jul;71(Pt 7):1423-32. doi: 10.1107/S1399004715007452. Epub 2015 Jun 30.

16.

Inhibition of catechol-O-methyl transferase (COMT) by tolcapone restores reductions in microtubule-associated protein 2 (MAP2) and synaptophysin (SYP) following exposure of neuronal cells to neurotropic HIV.

Lee TT, Chana G, Gorry PR, Ellett A, Bousman CA, Churchill MJ, Gray LR, Everall IP.

J Neurovirol. 2015 Oct;21(5):535-43. doi: 10.1007/s13365-015-0354-y. Epub 2015 Jun 3.

PMID:
26037113
17.

Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.

Sconce MD, Churchill MJ, Greene RE, Meshul CK.

Neuroscience. 2015 Jul 23;299:156-74. doi: 10.1016/j.neuroscience.2015.04.069. Epub 2015 May 2.

PMID:
25943481
18.

MPTP-induced parkinsonism in mice alters striatal and nigral xCT expression but is unaffected by the genetic loss of xCT.

Bentea E, Sconce MD, Churchill MJ, Van Liefferinge J, Sato H, Meshul CK, Massie A.

Neurosci Lett. 2015 Apr 23;593:1-6. doi: 10.1016/j.neulet.2015.03.013. Epub 2015 Mar 10.

PMID:
25766755
19.

HIV eradication symposium: will the brain be left behind?

Brew BJ, Robertson K, Wright EJ, Churchill M, Crowe SM, Cysique LA, Deeks S, Garcia JV, Gelman B, Gray LR, Johnson T, Joseph J, Margolis DM, Mankowski JL, Spencer B.

J Neurovirol. 2015 Jun;21(3):322-34. doi: 10.1007/s13365-015-0322-6. Epub 2015 Mar 7.

20.

Reliable genotypic tropism tests for the major HIV-1 subtypes.

Cashin K, Gray LR, Harvey KL, Perez-Bercoff D, Lee GQ, Sterjovski J, Roche M, Demarest JF, Drummond F, Harrigan PR, Churchill MJ, Gorry PR.

Sci Rep. 2015 Feb 25;5:8543. doi: 10.1038/srep08543.

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