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Results: 1 to 20 of 284

1.

Highly efficient Cas9-mediated transcriptional programming.

Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM.

Nat Methods. 2015 Mar 2. doi: 10.1038/nmeth.3312. [Epub ahead of print]

PMID:
25730490
[PubMed - as supplied by publisher]
2.

Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues.

Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Ferrante TC, Terry R, Turczyk BM, Yang JL, Lee HS, Aach J, Zhang K, Church GM.

Nat Protoc. 2015 Mar;10(3):442-58. doi: 10.1038/nprot.2014.191. Epub 2015 Feb 12.

PMID:
25675209
[PubMed - in process]
3.

Spatial information in large-scale neural recordings.

Cybulski TR, Glaser JI, Marblestone AH, Zamft BM, Boyden ES, Church GM, Kording KP.

Front Comput Neurosci. 2015 Jan 21;8:172. doi: 10.3389/fncom.2014.00172. eCollection 2014.

PMID:
25653613
[PubMed]
Free PMC Article
4.

Biocontainment of genetically modified organisms by synthetic protein design.

Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM.

Nature. 2015 Feb 5;518(7537):55-60. doi: 10.1038/nature14121. Epub 2015 Jan 21.

PMID:
25607366
[PubMed - indexed for MEDLINE]
5.

Insights into the evolution of longevity from the bowhead whale genome.

Keane M, Semeiks J, Webb AE, Li YI, Quesada V, Craig T, Madsen LB, van Dam S, Brawand D, Marques PI, Michalak P, Kang L, Bhak J, Yim HS, Grishin NV, Nielsen NH, Heide-Jørgensen MP, Oziolor EM, Matson CW, Church GM, Stuart GW, Patton JC, George JC, Suydam R, Larsen K, López-Otín C, O'Connell MJ, Bickham JW, Thomsen B, de Magalhães JP.

Cell Rep. 2015 Jan 6;10(1):112-22. doi: 10.1016/j.celrep.2014.12.008.

PMID:
25565328
[PubMed - in process]
Free Article
6.

Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68.

Yaung SJ, Esvelt KM, Church GM.

Genome Announc. 2015 Jan 2;3(1). pii: e01122-14. doi: 10.1128/genomeA.01122-14.

PMID:
25555735
[PubMed]
Free PMC Article
7.

Accurate whole genome sequencing as the ultimate genetic test.

Drmanac R, Peters BA, Church GM, Reid CA, Xu X.

Clin Chem. 2015 Jan;61(1):305-6. doi: 10.1373/clinchem.2014.224907. Epub 2014 Dec 5. No abstract available.

PMID:
25479756
[PubMed - in process]
8.

Evolution-guided optimization of biosynthetic pathways.

Raman S, Rogers JK, Taylor ND, Church GM.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17803-8. doi: 10.1073/pnas.1409523111. Epub 2014 Dec 1.

PMID:
25453111
[PubMed - in process]
Free PMC Article
9.

Multiple haplotype-resolved genomes reveal population patterns of gene and protein diplotypes.

Hoehe MR, Church GM, Lehrach H, Kroslak T, Palczewski S, Nowick K, Schulz S, Suk EK, Huebsch T.

Nat Commun. 2014 Nov 26;5:5569. doi: 10.1038/ncomms6569.

PMID:
25424553
[PubMed - in process]
Free PMC Article
10.

Multi-kilobase homozygous targeted gene replacement in human induced pluripotent stem cells.

Byrne SM, Ortiz L, Mali P, Aach J, Church GM.

Nucleic Acids Res. 2015 Feb 18;43(3):e21. doi: 10.1093/nar/gku1246. Epub 2014 Nov 20.

PMID:
25414332
[PubMed - in process]
Free Article
11.

Rapid neurogenesis through transcriptional activation in human stem cells.

Busskamp V, Lewis NE, Guye P, Ng AH, Shipman SL, Byrne SM, Sanjana NE, Murn J, Li Y, Li S, Stadler M, Weiss R, Church GM.

Mol Syst Biol. 2014 Nov 17;10:760. doi: 10.15252/msb.20145508.

PMID:
25403753
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Genome editing in human stem cells.

Byrne SM, Mali P, Church GM.

Methods Enzymol. 2014;546:119-38. doi: 10.1016/B978-0-12-801185-0.00006-4.

PMID:
25398338
[PubMed - in process]
13.

Engineering allostery.

Raman S, Taylor N, Genuth N, Fields S, Church GM.

Trends Genet. 2014 Dec;30(12):521-8. doi: 10.1016/j.tig.2014.09.004. Epub 2014 Oct 8. Review.

PMID:
25306102
[PubMed - in process]
14.

Multiplex single-molecule interaction profiling of DNA-barcoded proteins.

Gu L, Li C, Aach J, Hill DE, Vidal M, Church GM.

Nature. 2014 Nov 27;515(7528):554-7. doi: 10.1038/nature13761. Epub 2014 Sep 21.

PMID:
25252978
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Improved cell-free RNA and protein synthesis system.

Li J, Gu L, Aach J, Church GM.

PLoS One. 2014 Sep 2;9(9):e106232. doi: 10.1371/journal.pone.0106232. eCollection 2014.

PMID:
25180701
[PubMed - in process]
Free PMC Article
16.

The Naked Mole Rat Genome Resource: facilitating analyses of cancer and longevity-related adaptations.

Keane M, Craig T, Alföldi J, Berlin AM, Johnson J, Seluanov A, Gorbunova V, Di Palma F, Lindblad-Toh K, Church GM, de Magalhães JP.

Bioinformatics. 2014 Dec 15;30(24):3558-60. doi: 10.1093/bioinformatics/btu579. Epub 2014 Aug 28.

PMID:
25172923
[PubMed - in process]
Free PMC Article
17.

Concerning RNA-guided gene drives for the alteration of wild populations.

Esvelt KM, Smidler AL, Catteruccia F, Church GM.

Elife. 2014 Jul 17:e03401. doi: 10.7554/eLife.03401. [Epub ahead of print]

PMID:
25035423
[PubMed - as supplied by publisher]
Free PMC Article
18.

Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA).

Güell M, Yang L, Church GM.

Bioinformatics. 2014 Oct 15;30(20):2968-70. doi: 10.1093/bioinformatics/btu427. Epub 2014 Jul 1.

PMID:
24990609
[PubMed - indexed for MEDLINE]
19.

CRISPR/Cas9-Directed Genome Editing of Cultured Cells.

Yang L, Yang JL, Byrne S, Pan J, Church GM.

Curr Protoc Mol Biol. 2014 Jul 1;107:31.1.1-31.1.17. doi: 10.1002/0471142727.mb3101s107.

PMID:
24984853
[PubMed - in process]
20.

CRISPR/Cas9-mediated phage resistance is not impeded by the DNA modifications of phage T4.

Yaung SJ, Esvelt KM, Church GM.

PLoS One. 2014 Jun 2;9(6):e98811. doi: 10.1371/journal.pone.0098811. eCollection 2014.

PMID:
24886988
[PubMed - in process]
Free PMC Article
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