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Results: 1 to 20 of 114

1.

Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells.

Sastry KS, Al-Muftah MA, Li P, Al-Kowari MK, Wang E, Ismail Chouchane A, Kizhakayil D, Kulik G, Marincola FM, Haoudi A, Chouchane L.

Cell Death Differ. 2014 Sep 12. doi: 10.1038/cdd.2014.140. [Epub ahead of print]

PMID:
25215949
[PubMed - as supplied by publisher]
2.

The immune-related role of BRAF in melanoma.

Tomei S, Bedognetti D, De Giorgi V, Sommariva M, Civini S, Reinboth J, Al Hashmi M, Ascierto ML, Liu Q, Ayotte BD, Worschech A, Uccellini L, Ascierto PA, Stroncek D, Palmieri G, Chouchane L, Wang E, Marincola FM.

Mol Oncol. 2014 Aug 6. pii: S1574-7891(14)00169-0. doi: 10.1016/j.molonc.2014.07.014. [Epub ahead of print]

PMID:
25174651
[PubMed - as supplied by publisher]
Free Article
3.

Melanoma NOS1 expression promotes dysfunctional IFN signaling.

Liu Q, Tomei S, Ascierto ML, De Giorgi V, Bedognetti D, Dai C, Uccellini L, Spivey T, Pos Z, Thomas J, Reinboth J, Murtas D, Zhang Q, Chouchane L, Weiss GR, Slingluff CL Jr, Lee PP, Rosenberg SA, Alter H, Yao K, Wang E, Marincola FM.

J Clin Invest. 2014 May 1;124(5):2147-59. Epub 2014 Apr 1.

PMID:
24691438
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Longitudinal study of recurrent metastatic melanoma cell lines underscores the individuality of cancer biology.

Pos Z, Spivey TL, Liu H, Sommariva M, Chen J, Wunderlich JR, Parisi G, Tomei S, Ayotte BD, Stroncek DF, Malek JA, Robbins PF, Rivoltini L, Maio M, Chouchane L, Wang E, Marincola FM.

J Invest Dermatol. 2014 May;134(5):1389-96. doi: 10.1038/jid.2013.495. Epub 2013 Nov 22.

PMID:
24270663
[PubMed - indexed for MEDLINE]
5.

Prevalence of the apolipoprotein E Arg145Cys dyslipidemia at-risk polymorphism in African-derived populations.

Abou Ziki MD, Strulovici-Barel Y, Hackett NR, Rodriguez-Flores JL, Mezey JG, Salit J, Radisch S, Hollmann C, Chouchane L, Malek J, Zirie MA, Jayyuosi A, Gotto AM Jr, Crystal RG.

Am J Cardiol. 2014 Jan 15;113(2):302-8. doi: 10.1016/j.amjcard.2013.09.021. Epub 2013 Oct 3.

PMID:
24239320
[PubMed - indexed for MEDLINE]
6.

Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar.

Rodriguez-Flores JL, Fakhro K, Hackett NR, Salit J, Fuller J, Agosto-Perez F, Gharbiah M, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chouchane L, Stadler DJ, Mezey JG, Crystal RG.

Hum Mutat. 2014 Jan;35(1):105-16. doi: 10.1002/humu.22460. Epub 2013 Nov 10.

PMID:
24123366
[PubMed - indexed for MEDLINE]
7.

Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.

Galon J, Mlecnik B, Bindea G, Angell HK, Berger A, Lagorce C, Lugli A, Zlobec I, Hartmann A, Bifulco C, Nagtegaal ID, Palmqvist R, Masucci GV, Botti G, Tatangelo F, Delrio P, Maio M, Laghi L, Grizzi F, Asslaber M, D'Arrigo C, Vidal-Vanaclocha F, Zavadova E, Chouchane L, Ohashi PS, Hafezi-Bakhtiari S, Wouters BG, Roehrl M, Nguyen L, Kawakami Y, Hazama S, Okuno K, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Wang Y, Kopetz S, Sinicrope FA, Scripcariu V, Ascierto PA, Marincola FM, Fox BA, Pagès F.

J Pathol. 2014 Jan;232(2):199-209. doi: 10.1002/path.4287. Review.

PMID:
24122236
[PubMed - indexed for MEDLINE]
8.

Breast cancer in Arab populations: molecular characteristics and disease management implications.

Chouchane L, Boussen H, Sastry KS.

Lancet Oncol. 2013 Sep;14(10):e417-24. doi: 10.1016/S1470-2045(13)70165-7. Review.

PMID:
23993386
[PubMed - indexed for MEDLINE]
9.

IRF-1 responsiveness to IFN-γ predicts different cancer immune phenotypes.

Murtas D, Maric D, De Giorgi V, Reinboth J, Worschech A, Fetsch P, Filie A, Ascierto ML, Bedognetti D, Liu Q, Uccellini L, Chouchane L, Wang E, Marincola FM, Tomei S.

Br J Cancer. 2013 Jul 9;109(1):76-82. doi: 10.1038/bjc.2013.335. Epub 2013 Jun 27.

PMID:
23807161
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genome scan study of prostate cancer in Arabs: identification of three genomic regions with multiple prostate cancer susceptibility loci in Tunisians.

Shan J, Al-Rumaihi K, Rabah D, Al-Bozom I, Kizhakayil D, Farhat K, Al-Said S, Kfoury H, Dsouza SP, Rowe J, Khalak HG, Jafri S, Aigha II, Chouchane L.

J Transl Med. 2013 May 13;11:121. doi: 10.1186/1479-5876-11-121.

PMID:
23668334
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic polymorphisms in host innate immune sensor genes and the risk of nasopharyngeal carcinoma in North Africa.

Moumad K, Lascorz J, Bevier M, Khyatti M, Ennaji MM, Benider A, Huhn S, Lu S, Chouchane L, Corbex M, Hemminki K, Försti A.

G3 (Bethesda). 2013 Jun 21;3(6):971-7. doi: 10.1534/g3.112.005371.

PMID:
23576520
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

An overview of the statistical methods used for inferring gene regulatory networks and protein-protein interaction networks.

Noor A, Serpedin E, Nounou M, Nounou H, Mohamed N, Chouchane L.

Adv Bioinformatics. 2013;2013:953814. doi: 10.1155/2013/953814. Epub 2013 Feb 21.

PMID:
23509452
[PubMed]
Free PMC Article
13.

TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness.

Shan J, Dsouza SP, Bakhru S, Al-Azwani EK, Ascierto ML, Sastry KS, Bedri S, Kizhakayil D, Aigha II, Malek J, Al-Bozom I, Gehani S, Furtado S, Mathiowitz E, Wang E, Marincola FM, Chouchane L.

Cancer Res. 2013 May 1;73(9):2840-9. doi: 10.1158/0008-5472.CAN-12-4313. Epub 2013 Feb 27.

PMID:
23447579
[PubMed - indexed for MEDLINE]
Free Article
14.

Calreticulin expression in infiltrating ductal breast carcinomas: relationships with disease progression and humoral immune responses.

Kabbage M, Trimeche M, Bergaoui S, Hammann P, Kuhn L, Hamrita B, ben Nasr H, Chaieb A, Chouchane L, Chahed K.

Tumour Biol. 2013 Apr;34(2):1177-88. doi: 10.1007/s13277-013-0661-y. Epub 2013 Jan 22.

PMID:
23334957
[PubMed - indexed for MEDLINE]
15.

Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population.

Rodriguez-Flores JL, Fuller J, Hackett NR, Salit J, Malek JA, Al-Dous E, Chouchane L, Zirie M, Jayoussi A, Mahmoud MA, Crystal RG, Mezey JG.

PLoS One. 2012;7(11):e47614. doi: 10.1371/journal.pone.0047614. Epub 2012 Nov 6.

PMID:
23139751
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Cancer classification using the Immunoscore: a worldwide task force.

Galon J, Pagès F, Marincola FM, Angell HK, Thurin M, Lugli A, Zlobec I, Berger A, Bifulco C, Botti G, Tatangelo F, Britten CM, Kreiter S, Chouchane L, Delrio P, Arndt H, Asslaber M, Maio M, Masucci GV, Mihm M, Vidal-Vanaclocha F, Allison JP, Gnjatic S, Hakansson L, Huber C, Singh-Jasuja H, Ottensmeier C, Zwierzina H, Laghi L, Grizzi F, Ohashi PS, Shaw PA, Clarke BA, Wouters BG, Kawakami Y, Hazama S, Okuno K, Wang E, O'Donnell-Tormey J, Lagorce C, Pawelec G, Nishimura MI, Hawkins R, Lapointe R, Lundqvist A, Khleif SN, Ogino S, Gibbs P, Waring P, Sato N, Torigoe T, Itoh K, Patel PS, Shukla SN, Palmqvist R, Nagtegaal ID, Wang Y, D'Arrigo C, Kopetz S, Sinicrope FA, Trinchieri G, Gajewski TF, Ascierto PA, Fox BA.

J Transl Med. 2012 Oct 3;10:205. doi: 10.1186/1479-5876-10-205. Review.

PMID:
23034130
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Expression of the molecular chaperone αB-crystallin in infiltrating ductal breast carcinomas and the significance thereof: an immunohistochemical and proteomics-based strategy.

Kabbage M, Trimeche M, Ben Nasr H, Hammann P, Kuhn L, Hamrita B, Chaieb A, Chouchane L, Chahed K.

Tumour Biol. 2012 Dec;33(6):2279-88. doi: 10.1007/s13277-012-0490-4. Epub 2012 Sep 13.

PMID:
22972503
[PubMed - indexed for MEDLINE]
18.

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians.

Shan J, Mahfoudh W, Dsouza SP, Hassen E, Bouaouina N, Abdelhak S, Benhadjayed A, Memmi H, Mathew RA, Aigha II, Gabbouj S, Remadi Y, Chouchane L.

Breast Cancer Res Treat. 2012 Oct;135(3):715-24. doi: 10.1007/s10549-012-2202-6. Epub 2012 Aug 22.

PMID:
22910930
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Human Variome Project country nodes: documenting genetic information within a country.

Patrinos GP, Smith TD, Howard H, Al-Mulla F, Chouchane L, Hadjisavvas A, Hamed SA, Li XT, Marafie M, Ramesar RS, Ramos FJ, de Ravel T, El-Ruby MO, Shrestha TR, Sobrido MJ, Tadmouri G, Witsch-Baumgartner M, Zilfalil BA, Auerbach AD, Carpenter K, Cutting GR, Dung VC, Grody W, Hasler J, Jorde L, Kaput J, Macek M, Matsubara Y, Padilla C, Robinson H, Rojas-Martinez A, Taylor GR, Vihinen M, Weber T, Burn J, Qi M, Cotton RG, Rimoin D; International Confederation of Countries Advisory Council.

Hum Mutat. 2012 Nov;33(11):1513-9. doi: 10.1002/humu.22147. Epub 2012 Jul 18.

PMID:
22753370
[PubMed - indexed for MEDLINE]
20.

Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations.

Omberg L, Salit J, Hackett N, Fuller J, Matthew R, Chouchane L, Rodriguez-Flores JL, Bustamante C, Crystal RG, Mezey JG.

BMC Genet. 2012 Jun 26;13:49. doi: 10.1186/1471-2156-13-49.

PMID:
22734698
[PubMed - indexed for MEDLINE]
Free PMC Article

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