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Air pollution and adverse cardiac remodeling: clinical effects and basic mechanisms.

Liu Y, Goodson JM, Zhang B, Chin MT.

Front Physiol. 2015 May 20;6:162. doi: 10.3389/fphys.2015.00162. eCollection 2015. Review.


Ascending KLFs in cardiovascular biology.

Chin MT.

Trends Cardiovasc Med. 2015 May;25(4):288-90. doi: 10.1016/j.tcm.2014.12.003. Epub 2014 Dec 10. No abstract available.


Basic mechanisms for adverse cardiovascular events associated with air pollution.

Chin MT.

Heart. 2015 Feb;101(4):253-6. doi: 10.1136/heartjnl-2014-306379. Epub 2014 Dec 31. Review.


Reprogramming cell fate: a changing story.

Chin MT.

Front Cell Dev Biol. 2014 Aug 27;2:46. doi: 10.3389/fcell.2014.00046. eCollection 2014. Review.


Dose selection, pharmacokinetics, and pharmacodynamics of BRAF inhibitor dabrafenib (GSK2118436).

Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau HT, Brown MP, Hamid O, Infante JR, Millward M, Pavlick A, Chin MT, O'Day SJ, Blackman SC, Curtis CM, Lebowitz P, Ma B, Ouellet D, Kefford RF.

Clin Cancer Res. 2014 Sep 1;20(17):4449-58. doi: 10.1158/1078-0432.CCR-14-0887. Epub 2014 Jun 23.


Genomic DNA recombination with cell-penetrating peptide-tagged cre protein in mouse skeletal and cardiac muscle.

Chien WM, Liu Y, Chin MT.

Genesis. 2014 Jul;52(7):695-701. doi: 10.1002/dvg.22782. Epub 2014 May 5.


Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.

Hartman ME, Liu Y, Zhu WZ, Chien WM, Weldy CS, Fishman GI, Laflamme MA, Chin MT.

FASEB J. 2014 Jul;28(7):3007-15. doi: 10.1096/fj.14-251728. Epub 2014 Mar 31.


An optimized and simplified system of mouse embryonic stem cell cardiac differentiation for the assessment of differentiation modifiers.

Hartman ME, Librande JR, Medvedev IO, Ahmad RN, Moussavi-Harami F, Gupta PP, Chien WM, Chin MT.

PLoS One. 2014 Mar 25;9(3):e93033. doi: 10.1371/journal.pone.0093033. eCollection 2014.


In utero and early life exposure to diesel exhaust air pollution increases adult susceptibility to heart failure in mice.

Weldy CS, Liu Y, Chang YC, Medvedev IO, Fox JR, Larson TV, Chien WM, Chin MT.

Part Fibre Toxicol. 2013 Nov 26;10(1):59. doi: 10.1186/1743-8977-10-59.


Inhalation of diesel exhaust does not exacerbate cardiac hypertrophy or heart failure in two mouse models of cardiac hypertrophy.

Liu Y, Chien WM, Medvedev IO, Weldy CS, Luchtel DL, Rosenfeld ME, Chin MT.

Part Fibre Toxicol. 2013 Oct 5;10:49. doi: 10.1186/1743-8977-10-49.


Sodium-dependent phosphate cotransporters and phosphate-induced calcification of vascular smooth muscle cells: redundant roles for PiT-1 and PiT-2.

Crouthamel MH, Lau WL, Leaf EM, Chavkin NW, Wallingford MC, Peterson DF, Li X, Liu Y, Chin MT, Levi M, Giachelli CM.

Arterioscler Thromb Vasc Biol. 2013 Nov;33(11):2625-32. doi: 10.1161/ATVBAHA.113.302249. Epub 2013 Aug 22.


Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults.

Wilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW.

Mech Dev. 2013 Apr-May;130(4-5):272-89. doi: 10.1016/j.mod.2013.01.001. Epub 2013 Jan 24.


Is it possible to transform cardiac scar tissue into beating heart muscle in humans?

Chin MT, Murry CE.

Regen Med. 2012 Sep;7(5):623-5. doi: 10.2217/rme.12.54. Review. No abstract available.


Genetic modifiers predisposing to congenital heart disease in the sensitized Down syndrome population.

Li H, Cherry S, Klinedinst D, DeLeon V, Redig J, Reshey B, Chin MT, Sherman SL, Maslen CL, Reeves RH.

Circ Cardiovasc Genet. 2012 Jun;5(3):301-8. doi: 10.1161/CIRCGENETICS.111.960872. Epub 2012 Apr 20.


Transcription factor CHF1/Hey2 regulates EC coupling and heart failure in mice through regulation of FKBP12.6.

Liu Y, Korte FS, Moussavi-Harami F, Yu M, Razumova M, Regnier M, Chin MT.

Am J Physiol Heart Circ Physiol. 2012 May 1;302(9):H1860-70. doi: 10.1152/ajpheart.00702.2011. Epub 2012 Mar 9.


Regulation of MMP10 expression by the transcription factor CHF1/Hey2 is mediated by multiple E boxes.

Wu L, Chien WM, Hartman ME, Moussavi-Harami F, Liu Y, Chin MT.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):662-8. doi: 10.1016/j.bbrc.2011.10.132. Epub 2011 Nov 3.


Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress.

Dai DF, Hsieh EJ, Liu Y, Chen T, Beyer RP, Chin MT, MacCoss MJ, Rabinovitch PS.

Cardiovasc Res. 2012 Jan 1;93(1):79-88. doi: 10.1093/cvr/cvr274. Epub 2011 Oct 19.


Transforming growth factor-β signaling in myogenic cells regulates vascular morphogenesis, differentiation, and matrix synthesis.

Jaffe M, Sesti C, Washington IM, Du L, Dronadula N, Chin MT, Stolz DB, Davis EC, Dichek DA.

Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):e1-11. doi: 10.1161/ATVBAHA.111.238410. Epub 2011 Oct 6.


Differential role of Nkx2-5 in activation of the atrial natriuretic factor gene in the developing versus failing heart.

Warren SA, Terada R, Briggs LE, Cole-Jeffrey CT, Chien WM, Seki T, Weinberg EO, Yang TP, Chin MT, Bungert J, Kasahara H.

Mol Cell Biol. 2011 Nov;31(22):4633-45. doi: 10.1128/MCB.05940-11. Epub 2011 Sep 19.

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