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Intracellular Delivery of Proteins with Cell-Penetrating Peptides for Therapeutic Uses in Human Disease.

Dinca A, Chien WM, Chin MT.

Int J Mol Sci. 2016 Feb 22;17(2). pii: E263. doi: 10.3390/ijms17020263. Review.


Genomic DNA recombination with cell-penetrating peptide-tagged cre protein in mouse skeletal and cardiac muscle.

Chien WM, Liu Y, Chin MT.

Genesis. 2014 Jul;52(7):695-701. doi: 10.1002/dvg.22782. Epub 2014 May 5.


Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.

Hartman ME, Liu Y, Zhu WZ, Chien WM, Weldy CS, Fishman GI, Laflamme MA, Chin MT.

FASEB J. 2014 Jul;28(7):3007-15. doi: 10.1096/fj.14-251728. Epub 2014 Mar 31.


An optimized and simplified system of mouse embryonic stem cell cardiac differentiation for the assessment of differentiation modifiers.

Hartman ME, Librande JR, Medvedev IO, Ahmad RN, Moussavi-Harami F, Gupta PP, Chien WM, Chin MT.

PLoS One. 2014 Mar 25;9(3):e93033. doi: 10.1371/journal.pone.0093033. eCollection 2014.


In utero and early life exposure to diesel exhaust air pollution increases adult susceptibility to heart failure in mice.

Weldy CS, Liu Y, Chang YC, Medvedev IO, Fox JR, Larson TV, Chien WM, Chin MT.

Part Fibre Toxicol. 2013 Nov 26;10(1):59. doi: 10.1186/1743-8977-10-59.


Inhalation of diesel exhaust does not exacerbate cardiac hypertrophy or heart failure in two mouse models of cardiac hypertrophy.

Liu Y, Chien WM, Medvedev IO, Weldy CS, Luchtel DL, Rosenfeld ME, Chin MT.

Part Fibre Toxicol. 2013 Oct 5;10:49. doi: 10.1186/1743-8977-10-49.


Regulation of MMP10 expression by the transcription factor CHF1/Hey2 is mediated by multiple E boxes.

Wu L, Chien WM, Hartman ME, Moussavi-Harami F, Liu Y, Chin MT.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):662-8. doi: 10.1016/j.bbrc.2011.10.132. Epub 2011 Nov 3.


Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function.

Vázquez-Chona FR, Swan A, Ferrell WD, Jiang L, Baehr W, Chien WM, Fero M, Marc RE, Levine EM.

BMC Neurosci. 2011 Oct 10;12:98. doi: 10.1186/1471-2202-12-98.


Differential role of Nkx2-5 in activation of the atrial natriuretic factor gene in the developing versus failing heart.

Warren SA, Terada R, Briggs LE, Cole-Jeffrey CT, Chien WM, Seki T, Weinberg EO, Yang TP, Chin MT, Bungert J, Kasahara H.

Mol Cell Biol. 2011 Nov;31(22):4633-45. doi: 10.1128/MCB.05940-11. Epub 2011 Sep 19.


p27(Kip1) is required to maintain proliferative quiescence in the adult cochlea and pituitary.

Oesterle EC, Chien WM, Campbell S, Nellimarla P, Fero ML.

Cell Cycle. 2011 Apr 15;10(8):1237-48. Epub 2011 Apr 15.


High-pressure Raman spectroscopy of tris(hydroxymethyl)aminomethane.

Emmons ED, Fallas JC, Kamisetty VK, Chien WM, Covington AM, Chellappa RS, Gramsch SA, Hemley RJ, Chandra D.

J Phys Chem B. 2010 May 6;114(17):5649-56. doi: 10.1021/jp9092892.


Differential gene expression of p27Kip1 and Rb knockout pituitary tumors associated with altered growth and angiogenesis.

Chien WM, Garrison K, Caufield E, Orthel J, Dill J, Fero ML.

Cell Cycle. 2007 Mar 15;6(6):750-7. Epub 2007 Mar 7.


Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27Kip1.

Chien WM, Rabin S, Macias E, Miliani de Marval PL, Garrison K, Orthel J, Rodriguez-Puebla M, Fero ML.

Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4122-7. Epub 2006 Mar 3.


Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells.

Walkley CR, Fero ML, Chien WM, Purton LE, McArthur GA.

Nat Cell Biol. 2005 Feb;7(2):172-8. Epub 2005 Jan 16.


Global effects of human papillomavirus type 18 E6/E7 in an organotypic keratinocyte culture system.

Garner-Hamrick PA, Fostel JM, Chien WM, Banerjee NS, Chow LT, Broker TR, Fisher C.

J Virol. 2004 Sep;78(17):9041-50.


The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes.

Noya F, Chien WM, Wu X, Banerjee NS, Kappes JC, Broker TR, Chow LT.

J Biol Chem. 2002 May 10;277(19):17271-80. Epub 2002 Feb 27.


Alternative fates of keratinocytes transduced by human papillomavirus type 18 E7 during squamous differentiation.

Chien WM, Noya F, Benedict-Hamilton HM, Broker TR, Chow LT.

J Virol. 2002 Mar;76(6):2964-72.


Neurological abnormalities in a knock-in mouse model of Huntington's disease.

Lin CH, Tallaksen-Greene S, Chien WM, Cearley JA, Jackson WS, Crouse AB, Ren S, Li XJ, Albin RL, Detloff PJ.

Hum Mol Genet. 2001 Jan 15;10(2):137-44.

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