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Items: 1 to 20 of 118


G protein-coupled estrogen receptor inhibits the P2Y receptor-mediated Ca2+ signaling pathway in human airway epithelia.

Hao Y, Chow AW, Yip WC, Li CH, Wan TF, Tong BC, Cheung KH, Chan WY, Chen Y, Cheng CH, Ko WH.

Pflugers Arch. 2016 Jun 6. [Epub ahead of print]


Mechanistic Study of TRPM2-Ca2+-CAMK2-BECN1 Signaling in Oxidative Stress Induced Autophagy Inhibition.

Wang Q, Guo W, Hao B, Shi X, Lu Y, Wong CW, Ma VW, Yip TT, Au JS, Hao Q, Cheung KH, Wu W, Li GR, Yue J.

Autophagy. 2016 May 31:0. [Epub ahead of print]


Extending gene ontology in the context of extracellular RNA and vesicle communication.

Cheung KH, Keerthikumar S, Roncaglia P, Subramanian SL, Roth ME, Samuel M, Anand S, Gangoda L, Gould S, Alexander R, Galas D, Gerstein MB, Hill AF, Kitchen RR, Lötvall J, Patel T, Procaccini DC, Quesenberry P, Rozowsky J, Raffai RL, Shypitsyna A, Su AI, Théry C, Vickers K, Wauben MH, Mathivanan S, Milosavljevic A, Laurent LC.

J Biomed Semantics. 2016 Apr 12;7:19. doi: 10.1186/s13326-016-0061-5. eCollection 2016.


Impaired mitochondrial function due to familial Alzheimer's disease-causing presenilins mutants via Ca(2+) disruptions.

Toglia P, Cheung KH, Mak DO, Ullah G.

Cell Calcium. 2016 May;59(5):240-50. doi: 10.1016/j.ceca.2016.02.013. Epub 2016 Mar 5.


Technical Validation of a Next-Generation Sequencing Assay for Detecting Actionable Mutations in Patients with Gastrointestinal Cancer.

Wang SR, Malik S, Tan IB, Chan YS, Hoi Q, Ow JL, He CZ, Ching CE, Poh DY, Seah HM, Cheung KH, Perumal D, Devasia AG, Pan L, Ang S, Lee SE, Ten R, Chua C, Tan DS, Qu JZ, Bylstra YM, Lim L, Lezhava A, Ng PC, Wong CW, Lim T, Tan P.

J Mol Diagn. 2016 May;18(3):416-24. doi: 10.1016/j.jmoldx.2016.01.006. Epub 2016 Mar 9.


Characterization of Two-Pore Channel 2 by Nuclear Membrane Electrophysiology.

Lee CS, Tong BC, Cheng CW, Hung HC, Cheung KH.

Sci Rep. 2016 Feb 3;6:20282. doi: 10.1038/srep20282.


Analyzing and Quantifying the Gain-of-Function Enhancement of IP3 Receptor Gating by Familial Alzheimer's Disease-Causing Mutants in Presenilins.

Mak DO, Cheung KH, Toglia P, Foskett JK, Ullah G.

PLoS Comput Biol. 2015 Oct 6;11(10):e1004529. doi: 10.1371/journal.pcbi.1004529. eCollection 2015 Oct.


Role of copeptin in dual-cardiac marker strategy for patients with chest pain presented to ED.

Lui CT, Lam H, Cheung KH, Yip SF, Tsui KL, Kam CW, Chui KL, Yam PW, Morawiec B, Kawecki D.

Am J Emerg Med. 2015 Dec;33(12):1732-6. doi: 10.1016/j.ajem.2015.08.011. Epub 2015 Aug 10.


Integration of extracellular RNA profiling data using metadata, biomedical ontologies and Linked Data technologies.

Subramanian SL, Kitchen RR, Alexander R, Carter BS, Cheung KH, Laurent LC, Pico A, Roberts LR, Roth ME, Rozowsky JS, Su AI, Gerstein MB, Milosavljevic A.

J Extracell Vesicles. 2015 Aug 28;4:27497. doi: 10.3402/jev.v4.27497. eCollection 2015.


Gene-based and pathway-based genome-wide association study of alcohol dependence.

Zuo L, Zhang CK, Sayward FG, Cheung KH, Wang K, Krystal JH, Zhao H, Luo X.

Shanghai Arch Psychiatry. 2015 Apr 25;27(2):111-8. doi: 10.11919/j.issn.1002-0829.215031.


The center for expanded data annotation and retrieval.

Musen MA, Bean CA, Cheung KH, Dumontier M, Durante KA, Gevaert O, Gonzalez-Beltran A, Khatri P, Kleinstein SH, O'Connor MJ, Pouliot Y, Rocca-Serra P, Sansone SA, Wiser JA; CEDAR team.

J Am Med Inform Assoc. 2015 Nov;22(6):1148-52. doi: 10.1093/jamia/ocv048. Epub 2015 Jun 25.


A statistical framework to predict functional non-coding regions in the human genome through integrated analysis of annotation data.

Lu Q, Hu Y, Sun J, Cheng Y, Cheung KH, Zhao H.

Sci Rep. 2015 May 27;5:10576. doi: 10.1038/srep10576.


Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries.

Li RW, Yang C, Shan L, Zhang Z, Wang Y, Kwan YW, Lee SM, Hoi MP, Chan SW, Cheung AC, Cheung KH, Leung GP.

Eur J Pharmacol. 2015 Aug 15;761:153-60. doi: 10.1016/j.ejphar.2015.04.041. Epub 2015 May 4.


YPED: an integrated bioinformatics suite and database for mass spectrometry-based proteomics research.

Colangelo CM, Shifman M, Cheung KH, Stone KL, Carriero NJ, Gulcicek EE, Lam TT, Wu T, Bjornson RD, Bruce C, Nairn AC, Rinehart J, Miller PL, Williams KR.

Genomics Proteomics Bioinformatics. 2015 Feb;13(1):25-35. doi: 10.1016/j.gpb.2014.11.002. Epub 2015 Feb 21.


Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A.

Lu Y, Dong S, Hao B, Li C, Zhu K, Guo W, Wang Q, Cheung KH, Wong CW, Wu WT, Markus H, Yue J.

Autophagy. 2014;10(11):1895-905. doi: 10.4161/auto.32200. Epub 2014 Oct 30.


A spatial simulation approach to account for protein structure when identifying non-random somatic mutations.

Ryslik GA, Cheng Y, Cheung KH, Bjornson RD, Zelterman D, Modis Y, Zhao H.

BMC Bioinformatics. 2014 Jul 3;15:231. doi: 10.1186/1471-2105-15-231.


Adrenomedullin increases the short-circuit current in the mouse seminal vesicle: actions on chloride secretion.

Liao SB, Cheung KH, O WS, Tang F.

Biol Reprod. 2014 Aug;91(2):31. doi: 10.1095/biolreprod.113.116848. Epub 2014 Jun 4.


General anesthetic isoflurane modulates inositol 1,4,5-trisphosphate receptor calcium channel opening.

Joseph JD, Peng Y, Mak DO, Cheung KH, Vais H, Foskett JK, Wei H.

Anesthesiology. 2014 Sep;121(3):528-37. doi: 10.1097/ALN.0000000000000316.


Adrenomedullin increases the short-circuit current in the rat prostate: Receptors, chloride channels, the effects of cAMP and calcium ions and implications on fluid secretion.

Liao SB, Cheung KH, Cheung MP, Wong PF, O WS, Tang F.

Andrology. 2014 May;2(3):474-80. doi: 10.1111/j.2047-2927.2014.00189.x. Epub 2014 Apr 7.


A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations.

Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H.

BMC Bioinformatics. 2014 Mar 26;15:86. doi: 10.1186/1471-2105-15-86.

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