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Results: 1 to 20 of 153

1.

Potential Compensation among Group I PAK Members in Hindlimb Ischemia and Wound Healing.

Elsherif L, Ozler M, Zayed MA, Shen JH, Chernoff J, Faber JE, Parise LV.

PLoS One. 2014 Nov 7;9(11):e112239. doi: 10.1371/journal.pone.0112239. eCollection 2014.

PMID:
25379771
[PubMed - in process]
Free PMC Article
2.

Molecular Pathways: Targeting the Kinase Effectors of RHO-Family GTPases.

Prudnikova TY, Rawat SJ, Chernoff J.

Clin Cancer Res. 2014 Oct 21. pii: clincanres.0827.2014. [Epub ahead of print]

PMID:
25336694
[PubMed - as supplied by publisher]
3.

Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.

Badolia R, Manne BK, Dangelmaier C, Chernoff J, Kunapuli SP.

Blood. 2014 Oct 20. pii: blood-2014-05-576306. [Epub ahead of print]

PMID:
25331114
[PubMed - as supplied by publisher]
4.

Molecular pathways: targeting RAC-p21-activated serine-threonine kinase signaling in RAS-driven cancers.

Baker NM, Yee Chow H, Chernoff J, Der CJ.

Clin Cancer Res. 2014 Sep 15;20(18):4740-6. doi: 10.1158/1078-0432.CCR-13-1727.

PMID:
25225063
[PubMed - in process]
5.

Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.

Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A.

Elife. 2014 May 13;3:e02270. doi: 10.7554/eLife.02270.

PMID:
24843022
[PubMed - in process]
Free PMC Article
6.

A Pak1/Erk signaling module acts through Gata6 to regulate cardiovascular development in zebrafish.

Kelly ML, Astsaturov A, Rhodes J, Chernoff J.

Dev Cell. 2014 May 12;29(3):350-9. doi: 10.1016/j.devcel.2014.04.003.

PMID:
24823378
[PubMed - indexed for MEDLINE]
7.

Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice.

Chiang YT, Ip W, Shao W, Song ZE, Chernoff J, Jin T.

Endocrinology. 2014 Jun;155(6):2122-32. doi: 10.1210/en.2013-1743. Epub 2014 Mar 31.

PMID:
24684301
[PubMed - indexed for MEDLINE]
8.

PAK signalling during the development and progression of cancer.

Radu M, Semenova G, Kosoff R, Chernoff J.

Nat Rev Cancer. 2014 Jan;14(1):13-25. Review.

PMID:
24505617
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Analysis of PTP1B sumoylation.

Saha S, Chernoff J.

Methods. 2014 Jan 15;65(2):201-6. doi: 10.1016/j.ymeth.2013.09.012. Epub 2013 Sep 25.

PMID:
24076082
[PubMed - indexed for MEDLINE]
10.

p21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophils.

Itakura A, Aslan JE, Kusanto BT, Phillips KG, Porter JE, Newton PK, Nan X, Insall RH, Chernoff J, McCarty OJ.

PLoS One. 2013 Sep 3;8(9):e73063. doi: 10.1371/journal.pone.0073063. eCollection 2013.

PMID:
24019894
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

FRAX597, a small molecule inhibitor of the p21-activated kinases, inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas.

Licciulli S, Maksimoska J, Zhou C, Troutman S, Kota S, Liu Q, Duron S, Campbell D, Chernoff J, Field J, Marmorstein R, Kissil JL.

J Biol Chem. 2013 Oct 4;288(40):29105-14. doi: 10.1074/jbc.M113.510933. Epub 2013 Aug 19.

PMID:
23960073
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Targeting Cdc42 in cancer.

Arias-Romero LE, Chernoff J.

Expert Opin Ther Targets. 2013 Nov;17(11):1263-73. doi: 10.1517/14728222.2013.828037. Epub 2013 Aug 19. Review.

PMID:
23957315
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The PAK system links Rho GTPase signaling to thrombin-mediated platelet activation.

Aslan JE, Baker SM, Loren CP, Haley KM, Itakura A, Pang J, Greenberg DL, David LL, Manser E, Chernoff J, McCarty OJ.

Am J Physiol Cell Physiol. 2013 Sep;305(5):C519-28. doi: 10.1152/ajpcell.00418.2012. Epub 2013 Jun 19.

PMID:
23784547
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

ArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signaling.

Radu M, Rawat SJ, Beeser A, Iliuk A, Tao WA, Chernoff J.

J Biol Chem. 2013 Jul 19;288(29):21117-25. doi: 10.1074/jbc.M113.459719. Epub 2013 Jun 11.

PMID:
23760270
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Role of p21-activated kinases in cardiovascular development and function.

Kelly ML, Astsaturov A, Chernoff J.

Cell Mol Life Sci. 2013 Nov;70(22):4223-8. doi: 10.1007/s00018-013-1347-8. Epub 2013 May 4. Review.

PMID:
23640572
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear.

Aslan JE, Itakura A, Haley KM, Tormoen GW, Loren CP, Baker SM, Pang J, Chernoff J, McCarty OJ.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1544-51. doi: 10.1161/ATVBAHA.112.301165. Epub 2013 May 2.

PMID:
23640496
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.

Arias-Romero LE, Villamar-Cruz O, Huang M, Hoeflich KP, Chernoff J.

Cancer Res. 2013 Jun 15;73(12):3671-82. doi: 10.1158/0008-5472.CAN-12-4453. Epub 2013 Apr 10.

PMID:
23576562
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

An in vivo assay to test blood vessel permeability.

Radu M, Chernoff J.

J Vis Exp. 2013 Mar 16;(73):e50062. doi: 10.3791/50062.

PMID:
23524912
[PubMed - indexed for MEDLINE]
19.

The tumor suppressor Mst1 promotes changes in the cellular redox state by phosphorylation and inactivation of peroxiredoxin-1 protein.

Rawat SJ, Creasy CL, Peterson JR, Chernoff J.

J Biol Chem. 2013 Mar 22;288(12):8762-71. doi: 10.1074/jbc.M112.414524. Epub 2013 Feb 5.

PMID:
23386615
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

Dorrance AM, De Vita S, Radu M, Reddy PN, McGuinness MK, Harris CE, Mathieu R, Lane SW, Kosoff R, Milsom MD, Chernoff J, Williams DA.

Blood. 2013 Mar 28;121(13):2474-82. doi: 10.1182/blood-2012-10-460709. Epub 2013 Jan 18.

PMID:
23335370
[PubMed - indexed for MEDLINE]
Free PMC Article

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