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Nerolidol: A Sesquiterpene Alcohol with Multi-Faceted Pharmacological and Biological Activities.

Chan WK, Tan LT, Chan KG, Lee LH, Goh BH.

Molecules. 2016 Apr 28;21(5). pii: E529. doi: 10.3390/molecules21050529. Review.


Authors' reply.

Cho CL, Leung CL, Chan WK, Chu RW, Law IC.

Hong Kong Med J. 2016 Apr;22(2):188-9. No abstract available.


The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.

Shum EY, Jones SH, Shao A, Dumdie J, Krause MD, Chan WK, Lou CH, Espinoza JL, Song HW, Phan MH, Ramaiah M, Huang L, McCarrey JR, Peterson KJ, De Rooij DG, Cook-Andersen H, Wilkinson MF.

Cell. 2016 Apr 7;165(2):382-95. doi: 10.1016/j.cell.2016.02.046. Epub 2016 Mar 31.


Oxidized low-density lipoprotein in non-alcoholic steatohepatitis.

Chan WK, Wong VW.

J Gastroenterol Hepatol. 2016 Mar 25. doi: 10.1111/jgh.13381. [Epub ahead of print] No abstract available.


Asian Consensus on the relationship between Obesity and Gastrointestinal and Liver Diseases.

Koh JC, Loo WM, Goh KL, Sugano K, Chan WK, Chiu WY, Choi MG, Gonlachanvit S, Lee WJ, Lee WJ, Lee YY, Lesmana LA, Li YM, Liu CJ, Matsuura B, Nakajima A, Ng EK, Sollano JD, Wong SK, Wong VW, Yang Y, Ho KY, Dan YY; GOASIA Workgroup.

J Gastroenterol Hepatol. 2016 Mar 24. doi: 10.1111/jgh.13385. [Epub ahead of print] Review.


Selective suppression of the human aryl hydrocarbon receptor function can be mediated through binding interference at the C-terminal half of the receptor.

Ren L, Thompson JD, Cheung M, Ngo K, Sung S, Leong S, Chan WK.

Biochem Pharmacol. 2016 May 1;107:91-100. doi: 10.1016/j.bcp.2016.03.004. Epub 2016 Mar 9.


Binding studies using Pichia pastoris expressed human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins.

Zheng Y, Xie J, Huang X, Dong J, Park MS, Chan WK.

Protein Expr Purif. 2016 Jun;122:72-81. doi: 10.1016/j.pep.2016.02.011. Epub 2016 Feb 23.


The Protective Role of Autophagy in Matrix Metalloproteinase-Mediated Cell Transmigration and Cell Death in High-Glucose-Treated Endothelial Cells.

Chao CL, Chuang CP, Cheng YF, Lee KR, Chang Y, Cheng SP, Chan WK, Ho FM.

Inflammation. 2016 Apr;39(2):830-8. doi: 10.1007/s10753-016-0313-7.


Split-dose low-volume bowel preparation, a feasible option for preparation for colonoscopy.

Azmi AN, Chan WK, Mahadeva S, Goh KL.

Endoscopy. 2016 Feb;48(2):197. doi: 10.1055/s-0034-1393347. Epub 2016 Jan 28. No abstract available.


Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers.

Law BY, Mok SW, Chan WK, Xu SW, Wu AG, Yao XJ, Wang JR, Liu L, Wong VK.

Oncotarget. 2016 Feb 16;7(7):8090-104. doi: 10.18632/oncotarget.6980.


Clinical Characteristics, Management, and Outcomes of Acute Coronary Syndrome in Patients With Right Bundle Branch Block on Presentation.

Chan WK, Goodman SG, Brieger D, Fox KA, Gale CP, Chew DP, Udell JA, Lopez-Sendon J, Huynh T, Yan RT, Singh SM, Yan AT; ACS I and GRACE Investigators.

Am J Cardiol. 2016 Mar 1;117(5):754-9. doi: 10.1016/j.amjcard.2015.12.005. Epub 2015 Dec 12.


Early postoperative outcome of bipolar transurethral enucleation and resection of the prostate.

Cho CL, Leung CL, Chan WK, Chu RW, Law IC.

Hong Kong Med J. 2015 Dec;21(6):528-35. doi: 10.12809/hkmj144457. Epub 2015 Oct 16.


Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments.

Sun K, Jiang P, Chan KC, Wong J, Cheng YK, Liang RH, Chan WK, Ma ES, Chan SL, Cheng SH, Chan RW, Tong YK, Ng SS, Wong RS, Hui DS, Leung TN, Leung TY, Lai PB, Chiu RW, Lo YM.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5503-12. doi: 10.1073/pnas.1508736112. Epub 2015 Sep 21.


A biomimetic approach for enhancing the in vivo half-life of peptides.

Penchala SC, Miller MR, Pal A, Dong J, Madadi NR, Xie J, Joo H, Tsai J, Batoon P, Samoshin V, Franz A, Cox T, Miles J, Chan WK, Park MS, Alhamadsheh MM.

Nat Chem Biol. 2015 Oct;11(10):793-8. doi: 10.1038/nchembio.1907. Epub 2015 Sep 7.


Copy number variation in exportin-4 (XPO4) gene and its association with histological severity of non-alcoholic fatty liver disease.

Zain SM, Mohamed Z, Pirmohamed M, Tan HL, Alshawsh MA, Mahadeva S, Chan WK, Mustapha NR, Mohamed R.

Sci Rep. 2015 Aug 21;5:13306. doi: 10.1038/srep13306.


Sustained complete remission of advanced hepatocellular carcinoma with sorafenib therapy.

Azmi AN, Chan WK, Goh KL.

J Dig Dis. 2015 Sep;16(9):537-40. doi: 10.1111/1751-2980.12270. No abstract available.


Metal oxide nanoparticles with low toxicity.

Ng AM, Guo MY, Leung YH, Chan CM, Wong SW, Yung MM, Ma AP, Djurišić AB, Leung FC, Leung KM, Chan WK, Lee HK.

J Photochem Photobiol B. 2015 Oct;151:17-24. doi: 10.1016/j.jphotobiol.2015.06.020. Epub 2015 Jun 30.


Catalytic Role of the Substrate Defines Specificity of Therapeutic l-Asparaginase.

Anishkin A, Vanegas JM, Rogers DM, Lorenzi PL, Chan WK, Purwaha P, Weinstein JN, Sukharev S, Rempe SB.

J Mol Biol. 2015 Aug 28;427(17):2867-85. doi: 10.1016/j.jmb.2015.06.017. Epub 2015 Jul 2.


Narrow-band imaging and white-light endoscopy with optical magnification in the diagnosis of dysplasia in Barrett's esophagus: results of the Asia-Pacific Barrett's Consortium.

Singh R, Jayanna M, Wong J, Lim LG, Zhang J, Lv J, Liu D, Lee YC, Han ML, Tseng PH, Namasivayam V, Banerjee R, Uedo N, Chan WK, Ho SH, Chen SY, Bhatia S, Funasaka K, Ando T, Wu J, Lesmana C, Tam W, Wang WL, Chang CY, Jung HY, Jung KW, Bestari MB, Yao K, Chong VH, Sharma P, Ho KY.

Endosc Int Open. 2015 Feb;3(1):E14-8. doi: 10.1055/s-0034-1377610. Epub 2014 Sep 26.


Rapid memory T-cell reconstitution recapitulating CD45RA-depleted haploidentical transplant graft content in patients with hematologic malignancies.

Triplett BM, Shook DR, Eldridge P, Li Y, Kang G, Dallas M, Hartford C, Srinivasan A, Chan WK, Suwannasaen D, Inaba H, Merchant TE, Pui CH, Leung W.

Bone Marrow Transplant. 2015 Jul;50(7):1012. doi: 10.1038/bmt.2015.139. No abstract available.

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