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Results: 1 to 20 of 34

1.

Biophysics of protein evolution and evolutionary protein biophysics.

Sikosek T, Chan HS.

J R Soc Interface. 2014 Nov 6;11(100):20140419. doi: 10.1098/rsif.2014.0419.

PMID:
25165599
[PubMed - in process]
Free PMC Article
2.

Polycation-π interactions are a driving force for molecular recognition by an intrinsically disordered oncoprotein family.

Song J, Ng SC, Tompa P, Lee KA, Chan HS.

PLoS Comput Biol. 2013;9(9):e1003239. doi: 10.1371/journal.pcbi.1003239. Epub 2013 Sep 26.

PMID:
24086122
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Transition paths, diffusive processes, and preequilibria of protein folding.

Zhang Z, Chan HS.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20919-24. doi: 10.1073/pnas.1209891109. Epub 2012 Dec 3.

PMID:
23213246
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evolutionary dynamics on protein bi-stability landscapes can potentially resolve adaptive conflicts.

Sikosek T, Bornberg-Bauer E, Chan HS.

PLoS Comput Biol. 2012;8(9):e1002659. doi: 10.1371/journal.pcbi.1002659. Epub 2012 Sep 13.

PMID:
23028272
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Escape from Adaptive Conflict follows from weak functional trade-offs and mutational robustness.

Sikosek T, Chan HS, Bornberg-Bauer E.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14888-93. doi: 10.1073/pnas.1115620109. Epub 2012 Aug 27.

PMID:
22927372
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells.

Chan HS, Chang SJ, Wang TY, Ko HJ, Lin YC, Lin KT, Chang KM, Chuang YJ.

PLoS One. 2012;7(1):e30397. doi: 10.1371/journal.pone.0030397. Epub 2012 Jan 23.

PMID:
22291950
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Medical radiation exposure and risk of retinoblastoma resulting from new germline RB1 mutation.

Bunin GR, Felice MA, Davidson W, Friedman DL, Shields CL, Maidment A, O'Shea M, Nichols KE, Leahey A, Dunkel IJ, Jubran R, Rodriguez-Galindo C, Schmidt ML, Weinstein JL, Goldman S, Abramson DH, Wilson MW, Gallie BL, Chan HS, Shapiro M, Cnaan A, Ganguly A, Meadows AT.

Int J Cancer. 2011 May 15;128(10):2393-404. doi: 10.1002/ijc.25565.

PMID:
20648557
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Evolvability and single-genotype fluctuation in phenotypic properties: a simple heteropolymer model.

Chen T, Vernazobres D, Yomo T, Bornberg-Bauer E, Chan HS.

Biophys J. 2010 Jun 2;98(11):2487-96. doi: 10.1016/j.bpj.2010.02.046.

PMID:
20513392
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Local site preference rationalizes disentangling by DNA topoisomerases.

Liu Z, Zechiedrich L, Chan HS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2010 Mar;81(3 Pt 1):031902. Epub 2010 Mar 4.

PMID:
20365765
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Competition between native topology and nonnative interactions in simple and complex folding kinetics of natural and designed proteins.

Zhang Z, Chan HS.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2920-5. doi: 10.1073/pnas.0911844107. Epub 2010 Jan 29.

PMID:
20133730
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Liaison amid disorder: non-native interactions may underpin long-range coupling in proteins.

Chan HS, Zhang Z.

J Biol. 2009;8(3):27. doi: 10.1186/jbiol126. Epub 2009 Mar 13. Review.

PMID:
19344476
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The why and how of DNA unlinking.

Liu Z, Deibler RW, Chan HS, Zechiedrich L.

Nucleic Acids Res. 2009 Feb;37(3):661-71. doi: 10.1093/nar/gkp041. Review.

PMID:
19240147
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Native topology of the designed protein Top7 is not conducive to cooperative folding.

Zhang Z, Chan HS.

Biophys J. 2009 Feb;96(3):L25-7. doi: 10.1016/j.bpj.2008.11.004.

PMID:
19186118
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.

Zarrine-Afsar A, Wallin S, Neculai AM, Neudecker P, Howell PL, Davidson AR, Chan HS.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9999-10004. doi: 10.1073/pnas.0801874105. Epub 2008 Jul 14.

PMID:
18626019
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity.

Borg M, Mittag T, Pawson T, Tyers M, Forman-Kay JD, Chan HS.

Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9650-5. Epub 2007 May 23.

PMID:
17522259
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

A structural model of latent evolutionary potentials underlying neutral networks in proteins.

Wroe R, Chan HS, Bornberg-Bauer E.

HFSP J. 2007 May;1(1):79-87. doi: 10.2976/1.2739116/10.2976/1. Epub 2007 May 21.

PMID:
19404462
[PubMed]
Free PMC Article
17.

Hydrophobic association of alpha-helices, steric dewetting, and enthalpic barriers to protein folding.

MacCallum JL, Moghaddam MS, Chan HS, Tieleman DP.

Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6206-10. Epub 2007 Apr 2. Erratum in: Proc Natl Acad Sci U S A. 2008 Dec 9;105(49):19561.

PMID:
17404236
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Inferring global topology from local juxtaposition geometry: interlinking polymer rings and ramifications for topoisomerase action.

Liu Z, Zechiedrich EL, Chan HS.

Biophys J. 2006 Apr 1;90(7):2344-55.

PMID:
16537549
[PubMed - indexed for MEDLINE]
Free PMC Article
19.
20.

Chevron behavior and isostable enthalpic barriers in protein folding: successes and limitations of simple Gō-like modeling.

Kaya H, Liu Z, Chan HS.

Biophys J. 2005 Jul;89(1):520-35. Epub 2005 Apr 29.

PMID:
15863486
[PubMed - indexed for MEDLINE]
Free PMC Article

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