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The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.

Novo CL, Tang C, Ahmed K, Djuric U, Fussner E, Mullin NP, Morgan NP, Hayre J, Sienerth AR, Elderkin S, Nishinakamura R, Chambers I, Ellis J, Bazett-Jones DP, Rugg-Gunn PJ.

Genes Dev. 2016 Apr 28. [Epub ahead of print]


In-house development of a dedicated data acquisition and monitoring system for intracranial pressure, patient posture and patient symptoms in a regional neurosciences centre.

Marsden SP, Boddy IJ, Strachan RD, Chambers IR.

Physiol Meas. 2016 Feb;37(2):N1-N10. doi: 10.1088/0967-3334/37/2/N1. Epub 2016 Jan 15.


Surgical Trial In Traumatic intraCerebral Haemorrhage (STITCH): a randomised controlled trial of Early Surgery compared with Initial Conservative Treatment.

Gregson BA, Rowan EN, Francis R, McNamee P, Boyers D, Mitchell P, McColl E, Chambers IR, Unterberg A, Mendelow AD; STITCH(TRAUMA) investigators.

Health Technol Assess. 2015 Sep;19(70):1-138. doi: 10.3310/hta19700.


Reprogramming Roadblocks Are System Dependent.

Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K.

Stem Cell Reports. 2015 Sep 8;5(3):350-64. doi: 10.1016/j.stemcr.2015.07.007. Epub 2015 Aug 13.


Selective influence of Sox2 on POU transcription factor binding in embryonic and neural stem cells.

Mistri TK, Devasia AG, Chu LT, Ng WP, Halbritter F, Colby D, Martynoga B, Tomlinson SR, Chambers I, Robson P, Wohland T.

EMBO Rep. 2015 Sep;16(9):1177-91. doi: 10.15252/embr.201540467. Epub 2015 Aug 11.


Clinical pathologic conference case 4: just an extravasation mucocele?

Aldred MJ, Talacko AA, Hall GM, Chambers IG.

Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 May;119(5):e284-7. No abstract available.


Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury.

Güiza F, Depreitere B, Piper I, Citerio G, Chambers I, Jones PA, Lo TY, Enblad P, Nillson P, Feyen B, Jorens P, Maas A, Schuhmann MU, Donald R, Moss L, Van den Berghe G, Meyfroidt G.

Intensive Care Med. 2015 Jun;41(6):1067-76. doi: 10.1007/s00134-015-3806-1. Epub 2015 Apr 18.


Early Surgery versus Initial Conservative Treatment in Patients with Traumatic Intracerebral Hemorrhage (STITCH[Trauma]): The First Randomized Trial.

Mendelow AD, Gregson BA, Rowan EN, Francis R, McColl E, McNamee P, Chambers IR, Unterberg A, Boyers D, Mitchell PM; STITCH(Trauma) Investigators.

J Neurotrauma. 2015 Sep 1;32(17):1312-23. doi: 10.1089/neu.2014.3644. Epub 2015 May 21.


A signal-to-cutoff ratio in the Abbott architect HIV Ag/Ab Combo assay that predicts subsequent confirmation of HIV-1 infection in a low-prevalence setting.

Jensen TO, Robertson P, Whybin R, Chambers I, Lahra M, Rawlinson W, Post JJ.

J Clin Microbiol. 2015 May;53(5):1709-11. doi: 10.1128/JCM.03583-14. Epub 2015 Feb 11.


Lessons in learning: An effective process for engaging 12- to 14-year-olds in stem cell biology.

Kemp E, Chambers I.

EMBO Rep. 2015 Jan;16(1):7-13. doi: 10.15252/embr.201439398. Epub 2014 Dec 17. No abstract available.


Update on patterns of mandibular fracture in Tasmania, Australia.

Verma S, Chambers I.

Br J Oral Maxillofac Surg. 2015 Jan;53(1):74-7. doi: 10.1016/j.bjoms.2014.10.003. Epub 2014 Nov 1.


Dental emergencies presenting to a general hospital emergency department in Hobart, Australia.

Verma S, Chambers I.

Aust Dent J. 2014 Sep;59(3):329-33. doi: 10.1111/adj.12202. Epub 2014 Jul 22.


Environmental gestagens activate fathead minnow (Pimephales promelas) nuclear progesterone and androgen receptors in vitro.

Ellestad LE, Cardon M, Chambers IG, Farmer JL, Hartig P, Stevens K, Villeneuve DL, Wilson V, Orlando EF.

Environ Sci Technol. 2014 Jul 15;48(14):8179-87. doi: 10.1021/es501428u. Epub 2014 Jun 24.


Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage.

Torres-Padilla ME, Chambers I.

Development. 2014 Jun;141(11):2173-81. doi: 10.1242/dev.102624. Review.


The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell states.

Festuccia N, Osorno R, Wilson V, Chambers I.

Curr Opin Genet Dev. 2013 Oct;23(5):504-11. doi: 10.1016/j.gde.2013.06.003. Epub 2013 Aug 7. Review.


A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

Gagliardi A, Mullin NP, Ying Tan Z, Colby D, Kousa AI, Halbritter F, Weiss JT, Felker A, Bezstarosti K, Favaro R, Demmers J, Nicolis SK, Tomlinson SR, Poot RA, Chambers I.

EMBO J. 2013 Aug 14;32(16):2231-47. doi: 10.1038/emboj.2013.161. Epub 2013 Jul 26.


The pluripotent genome in three dimensions is shaped around pluripotency factors.

de Wit E, Bouwman BA, Zhu Y, Klous P, Splinter E, Verstegen MJ, Krijger PH, Festuccia N, Nora EP, Welling M, Heard E, Geijsen N, Poot RA, Chambers I, de Laat W.

Nature. 2013 Sep 12;501(7466):227-31. doi: 10.1038/nature12420. Epub 2013 Jul 24.


Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.

Zhou X, Smith AJ, Waterhouse A, Blin G, Malaguti M, Lin CY, Osorno R, Chambers I, Lowell S.

Stem Cells. 2013 Aug;31(8):1511-22. doi: 10.1002/stem.1426.


Reduced Oct4 expression directs a robust pluripotent state with distinct signaling activity and increased enhancer occupancy by Oct4 and Nanog.

Karwacki-Neisius V, Göke J, Osorno R, Halbritter F, Ng JH, Weiße AY, Wong FC, Gagliardi A, Mullin NP, Festuccia N, Colby D, Tomlinson SR, Ng HH, Chambers I.

Cell Stem Cell. 2013 May 2;12(5):531-45. doi: 10.1016/j.stem.2013.04.023.


A multi-parameter system for use in neonatal resuscitation research and training.

Platten CR, Wood FE, Chambers IR.

J Med Eng Technol. 2013 Jan;37(1):22-7. doi: 10.3109/03091902.2012.728675. Epub 2012 Dec 8.

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