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Results: 1 to 20 of 38

1.

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels.

Allen M, Kachadoorian M, Quicksall Z, Zou F, Chai HS, Younkin C, Crook JE, Pankratz VS, Carrasquillo MM, Krishnan S, Nguyen T, Ma L, Malphrus K, Lincoln S, Bisceglio G, Kolbert CP, Jen J, Mukherjee S, Kauwe JK, Crane PK, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Parisi JE, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

Alzheimers Res Ther. 2014 Jul 1;6(4):39. doi: 10.1186/alzrt268. eCollection 2014.

PMID:
25324900
[PubMed]
Free PMC Article
2.

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.

De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA.

Nat Neurosci. 2014 Sep;17(9):1156-63. doi: 10.1038/nn.3786. Epub 2014 Aug 17.

PMID:
25129075
[PubMed - in process]
3.

An integrated model of the transcriptome of HER2-positive breast cancer.

Kalari KR, Necela BM, Tang X, Thompson KJ, Lau M, Eckel-Passow JE, Kachergus JM, Anderson SK, Sun Z, Baheti S, Carr JM, Baker TR, Barman P, Radisky DC, Joseph RW, McLaughlin SA, Chai HS, Camille S, Rossell D, Asmann YW, Thompson EA, Perez EA.

PLoS One. 2013 Nov 1;8(11):e79298. doi: 10.1371/journal.pone.0079298. eCollection 2013.

PMID:
24223926
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Elevated cardiac troponin T levels in critically ill patients with sepsis.

Vasile VC, Chai HS, Abdeldayem D, Afessa B, Jaffe AS.

Am J Med. 2013 Dec;126(12):1114-21. doi: 10.1016/j.amjmed.2013.06.029. Epub 2013 Sep 28.

PMID:
24083646
[PubMed - indexed for MEDLINE]
5.

Response to genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

Chai HS, Chapman AB, Boerwinkle E.

Hypertension. 2013 Jan;61(1):e6. No abstract available.

PMID:
23362515
[PubMed - indexed for MEDLINE]
Free Article
6.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD; Alzheimer's Disease Genetics Consortium, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

Neurology. 2012 Jul 17;79(3):221-8. doi: 10.1212/WNL.0b013e3182605801. Epub 2012 Jun 20.

PMID:
22722634
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.

Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD; Alzheimer's Disease Genetics Consortium, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

PLoS Genet. 2012;8(6):e1002707. doi: 10.1371/journal.pgen.1002707. Epub 2012 Jun 7.

PMID:
22685416
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Deep Sequence Analysis of Non-Small Cell Lung Cancer: Integrated Analysis of Gene Expression, Alternative Splicing, and Single Nucleotide Variations in Lung Adenocarcinomas with and without Oncogenic KRAS Mutations.

Kalari KR, Rossell D, Necela BM, Asmann YW, Nair A, Baheti S, Kachergus JM, Younkin CS, Baker T, Carr JM, Tang X, Walsh MP, Chai HS, Sun Z, Hart SN, Leontovich AA, Hossain A, Kocher JP, Perez EA, Reisman DN, Fields AP, Thompson EA.

Front Oncol. 2012 Feb 10;2:12. doi: 10.3389/fonc.2012.00012. eCollection 2012.

PMID:
22655260
[PubMed]
Free PMC Article
9.

Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

Turner ST, Bailey KR, Schwartz GL, Chapman AB, Chai HS, Boerwinkle E.

Hypertension. 2012 Jun;59(6):1204-11. doi: 10.1161/HYP.0b013e31825b30f8. Epub 2012 May 7.

PMID:
22566498
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications.

Allen M, Zou F, Chai HS, Younkin CS, Miles R, Nair AA, Crook JE, Pankratz VS, Carrasquillo MM, Rowley CN, Nguyen T, Ma L, Malphrus KG, Bisceglio G, Ortolaza AI, Palusak R, Middha S, Maharjan S, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Sando SB, Aasly JO, Barcikowska M, Uitti RJ, Wszolek ZK, Ross OA, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N.

Mol Neurodegener. 2012 Apr 11;7:13. doi: 10.1186/1750-1326-7-13.

PMID:
22494505
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Improvement of optical trapping effect by using the focused high-order Laguerre-Gaussian beams.

Chai HS, Wang LG.

Micron. 2012 Aug;43(8):887-92. doi: 10.1016/j.micron.2012.03.004. Epub 2012 Mar 13.

PMID:
22464742
[PubMed]
12.

Concordance of changes in metabolic pathways based on plasma metabolomics and skeletal muscle transcriptomics in type 1 diabetes.

Dutta T, Chai HS, Ward LE, Ghosh A, Persson XM, Ford GC, Kudva YC, Sun Z, Asmann YW, Kocher JP, Nair KS.

Diabetes. 2012 May;61(5):1004-16. doi: 10.2337/db11-0874. Epub 2012 Mar 13.

PMID:
22415876
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Germline predictors of androgen deprivation therapy response in advanced prostate cancer.

Kohli M, Riska SM, Mahoney DW, Chai HS, Hillman DW, Rider DN, Costello BA, Qin R, Lamba J, Sahasrabudhe DM, Cerhan JR.

Mayo Clin Proc. 2012 Mar;87(3):240-6. doi: 10.1016/j.mayocp.2011.09.009.

PMID:
22386179
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Impact of data fragmentation across healthcare centers on the accuracy of a high-throughput clinical phenotyping algorithm for specifying subjects with type 2 diabetes mellitus.

Wei WQ, Leibson CL, Ransom JE, Kho AN, Caraballo PJ, Chai HS, Yawn BP, Pacheco JA, Chute CG.

J Am Med Inform Assoc. 2012 Mar-Apr;19(2):219-24. doi: 10.1136/amiajnl-2011-000597. Epub 2012 Jan 16.

PMID:
22249968
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Batch effect correction for genome-wide methylation data with Illumina Infinium platform.

Sun Z, Chai HS, Wu Y, White WM, Donkena KV, Klein CJ, Garovic VD, Therneau TM, Kocher JP.

BMC Med Genomics. 2011 Dec 16;4:84. doi: 10.1186/1755-8794-4-84.

PMID:
22171553
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

TREAT: a bioinformatics tool for variant annotations and visualizations in targeted and exome sequencing data.

Asmann YW, Middha S, Hossain A, Baheti S, Li Y, Chai HS, Sun Z, Duffy PH, Hadad AA, Nair A, Liu X, Zhang Y, Klee EW, Kalari KR, Kocher JP.

Bioinformatics. 2012 Jan 15;28(2):277-8. doi: 10.1093/bioinformatics/btr612. Epub 2011 Nov 15.

PMID:
22088845
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Association of TNFSF8 polymorphisms with peripheral neutrophil count.

Arruda-Olson AM, Roger VL, Chai HS, de Andrade M, Fridley BL, Cunningham JM, Gabriel SE, Bielinski SJ.

Mayo Clin Proc. 2011 Nov;86(11):1075-81. doi: 10.4065/mcp.2011.0275.

PMID:
22033252
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.

Denny JC, Crawford DC, Ritchie MD, Bielinski SJ, Basford MA, Bradford Y, Chai HS, Bastarache L, Zuvich R, Peissig P, Carrell D, Ramirez AH, Pathak J, Wilke RA, Rasmussen L, Wang X, Pacheco JA, Kho AN, Hayes MG, Weston N, Matsumoto M, Kopp PA, Newton KM, Jarvik GP, Li R, Manolio TA, Kullo IJ, Chute CG, Chisholm RL, Larson EB, McCarty CA, Masys DR, Roden DM, de Andrade M.

Am J Hum Genet. 2011 Oct 7;89(4):529-42. doi: 10.1016/j.ajhg.2011.09.008.

PMID:
21981779
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Homozygosity mapping and exome sequencing reveal GATAD1 mutation in autosomal recessive dilated cardiomyopathy.

Theis JL, Sharpe KM, Matsumoto ME, Chai HS, Nair AA, Theis JD, de Andrade M, Wieben ED, Michels VV, Olson TM.

Circ Cardiovasc Genet. 2011 Dec;4(6):585-94. doi: 10.1161/CIRCGENETICS.111.961052. Epub 2011 Sep 30.

PMID:
21965549
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Revisit on dynamic radiation forces induced by pulsed Gaussian beams.

Wang LG, Chai HS.

Opt Express. 2011 Jul 18;19(15):14389-402. doi: 10.1364/OE.19.014389.

PMID:
21934801
[PubMed]
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