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Results: 1 to 20 of 196

1.

Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia.

Chitta K, Paulus A, Caulfield TR, Akhtar S, Blake MK, Ailawadhi S, Knight J, Heckman MG, Pinkerton A, Chanan-Khan A.

Blood Cancer J. 2014 Nov 7;4:e260. doi: 10.1038/bcj.2014.74.

PMID:
25382610
[PubMed - in process]
2.

Phosphorylation by PINK1 Releases the UBL Domain and Initializes the Conformational Opening of the E3 Ubiquitin Ligase Parkin.

Caulfield TR, Fiesel FC, Moussaud-Lamodière EL, Dourado DF, Flores SC, Springer W.

PLoS Comput Biol. 2014 Nov 6;10(11):e1003935. doi: 10.1371/journal.pcbi.1003935. eCollection 2014 Nov.

PMID:
25375667
[PubMed - in process]
Free PMC Article
3.

Physician liability and non-invasive prenatal testing.

Toews M, Caulfield T.

J Obstet Gynaecol Can. 2014 Oct;36(10):907-14.

PMID:
25375305
[PubMed - in process]
4.

Professional regulation: a potentially valuable tool in responding to "stem cell tourism".

Zarzeczny A, Caulfield T, Ogbogu U, Bell P, Crooks VA, Kamenova K, Master Z, Rachul C, Snyder J, Toews M, Zoeller S.

Stem Cell Reports. 2014 Sep 9;3(3):379-84. doi: 10.1016/j.stemcr.2014.06.016. Epub 2014 Jul 31.

PMID:
25241736
[PubMed - in process]
Free Article
5.

Stem cell tourism and public education: the missing elements.

Master Z, Robertson K, Frederick D, Rachul C, Caulfield T.

Cell Stem Cell. 2014 Sep 4;15(3):267-70. doi: 10.1016/j.stem.2014.08.009.

PMID:
25192461
[PubMed - in process]
6.

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.

Zhang YJ, Jansen-West K, Xu YF, Gendron TF, Bieniek KF, Lin WL, Sasaguri H, Caulfield T, Hubbard J, Daughrity L, Chew J, Belzil VV, Prudencio M, Stankowski JN, Castanedes-Casey M, Whitelaw E, Ash PE, DeTure M, Rademakers R, Boylan KB, Dickson DW, Petrucelli L.

Acta Neuropathol. 2014 Oct;128(4):505-24. doi: 10.1007/s00401-014-1336-5. Epub 2014 Aug 31.

PMID:
25173361
[PubMed - in process]
Free PMC Article
7.

Newspaper coverage of biobanks.

Ogbogu U, Toews M, Ollenberger A, Borry P, Nobile H, Bergmann M, Caulfield T.

PeerJ. 2014 Jul 31;2:e500. doi: 10.7717/peerj.500. eCollection 2014.

PMID:
25101229
[PubMed]
Free PMC Article
8.

Scientists' perspectives on consent in the context of biobanking research.

Master Z, Campo-Engelstein L, Caulfield T.

Eur J Hum Genet. 2014 Jul 30. doi: 10.1038/ejhg.2014.143. [Epub ahead of print]

PMID:
25074466
[PubMed - as supplied by publisher]
9.

Defining 'medical necessity' in an age of personalised medicine: A view from Canada.

Caulfield T, Zarzeczny A.

Bioessays. 2014 Sep;36(9):813-7. doi: 10.1002/bies.201400073. Epub 2014 Jul 24.

PMID:
25059840
[PubMed - in process]
10.

Representations of stem cell clinics on twitter.

Kamenova K, Reshef A, Caulfield T.

Stem Cell Rev. 2014 Dec;10(6):753-60. doi: 10.1007/s12015-014-9534-z.

PMID:
24970380
[PubMed - in process]
11.

Industry involvement in publicly funded biobanks.

Caulfield T, Borry P, Gottweis H.

Nat Rev Genet. 2014 Apr;15(4):220. doi: 10.1038/nrg3704. No abstract available.

PMID:
24772494
[PubMed - indexed for MEDLINE]
12.

Human genetic research, race, ethnicity and the labeling of populations: recommendations based on an interdisciplinary workshop in Japan.

Takezawa Y, Kato K, Oota H, Caulfield T, Fujimoto A, Honda S, Kamatani N, Kawamura S, Kawashima K, Kimura R, Matsumae H, Saito A, Savage PE, Seguchi N, Shimizu K, Terao S, Yamaguchi-Kabata Y, Yasukouchi A, Yoneda M, Tokunaga K.

BMC Med Ethics. 2014 Apr 23;15:33. doi: 10.1186/1472-6939-15-33.

PMID:
24758583
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Economic consequences incurred by living kidney donors: a Canadian multi-center prospective study.

Klarenbach S, Gill JS, Knoll G, Caulfield T, Boudville N, Prasad GV, Karpinski M, Storsley L, Treleaven D, Arnold J, Cuerden M, Jacobs P, Garg AX; Donor Nephrectomy Outcomes Research (DONOR) Network.

Am J Transplant. 2014 Apr;14(4):916-22. doi: 10.1111/ajt.12662. Epub 2014 Mar 5.

PMID:
24597854
[PubMed - in process]
Free Article
14.

Policy recommendations for addressing privacy challenges associated with cell-based research and interventions.

Ogbogu U, Burningham S, Ollenberger A, Calder K, Du L, El Emam K, Hyde-Lay R, Isasi R, Joly Y, Kerr I, Malin B, McDonald M, Penney S, Piat G, Roy DC, Sugarman J, Vercauteren S, Verhenneman G, West L, Caulfield T.

BMC Med Ethics. 2014 Feb 3;15:7. doi: 10.1186/1472-6939-15-7.

PMID:
24485220
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Angelina Jolie's faulty gene: newspaper coverage of a celebrity's preventive bilateral mastectomy in Canada, the United States, and the United Kingdom.

Kamenova K, Reshef A, Caulfield T.

Genet Med. 2014 Jul;16(7):522-8. doi: 10.1038/gim.2013.199. Epub 2013 Dec 19.

PMID:
24357851
[PubMed - in process]
16.

Commercialization and stem cell research: a review of emerging issues.

Burningham S, Ollenberger A, Caulfield T.

Stem Cells Dev. 2013 Dec;22 Suppl 1:80-4. doi: 10.1089/scd.2013.0317.

PMID:
24304081
[PubMed - indexed for MEDLINE]
17.

Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate.

Caulfield T, Evans J, McGuire A, McCabe C, Bubela T, Cook-Deegan R, Fishman J, Hogarth S, Miller FA, Ravitsky V, Biesecker B, Borry P, Cho MK, Carroll JC, Etchegary H, Joly Y, Kato K, Lee SS, Rothenberg K, Sankar P, Szego MJ, Ossorio P, Pullman D, Rousseau F, Ungar WJ, Wilson B.

PLoS Biol. 2013 Nov;11(11):e1001699. doi: 10.1371/journal.pbio.1001699. Epub 2013 Nov 5.

PMID:
24223516
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Financial incentives to increase Canadian organ donation: quick fix or fallacy?

Gill JS, Klarenbach S, Barnieh L, Caulfield T, Knoll G, Levin A, Cole EH.

Am J Kidney Dis. 2014 Jan;63(1):133-40. doi: 10.1053/j.ajkd.2013.08.029. Epub 2013 Nov 5.

PMID:
24200461
[PubMed - indexed for MEDLINE]
19.

Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.

Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, Gao FB, Petrucelli L.

Hum Mol Genet. 2014 Mar 15;23(6):1467-78. doi: 10.1093/hmg/ddt534. Epub 2013 Oct 26.

PMID:
24163244
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.

Gendron TF, Bieniek KF, Zhang YJ, Jansen-West K, Ash PE, Caulfield T, Daughrity L, Dunmore JH, Castanedes-Casey M, Chew J, Cosio DM, van Blitterswijk M, Lee WC, Rademakers R, Boylan KB, Dickson DW, Petrucelli L.

Acta Neuropathol. 2013 Dec;126(6):829-44. doi: 10.1007/s00401-013-1192-8. Epub 2013 Oct 16.

PMID:
24129584
[PubMed - indexed for MEDLINE]
Free PMC Article

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