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Results: 1 to 20 of 206

1.

Structural and Functional Impact of Parkinson Disease-Associated Mutations in the E3 Ubiquitin Ligase Parkin.

Fiesel FC, Caulfield TR, Moussaud-Lamodière EL, Dourado KO, Flores SC, Ross OA, Springer W.

Hum Mutat. 2015 May 5. doi: 10.1002/humu.22808. [Epub ahead of print]

PMID:
25939424
2.

The Fountain of Stem Cell-Based Youth? Online Portrayals of Anti-Aging Stem Cell Technologies.

Rachul CM, Percec I, Caulfield T.

Aesthet Surg J. 2015 Apr 28. pii: sju111. [Epub ahead of print] No abstract available.

PMID:
25922365
3.

Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15.

Wang X, D'Arcy P, Caulfield TR, Paulus A, Chitta K, Mohanty C, Gullbo J, Chanan-Khan A, Linder S.

Chem Biol Drug Des. 2015 Apr 9. doi: 10.1111/cbdd.12571. [Epub ahead of print]

PMID:
25854145
4.

Activation of the E3 ubiquitin ligase Parkin.

Caulfield TR, Fiesel FC, Springer W.

Biochem Soc Trans. 2015 Apr 1;43(2):269-74. doi: 10.1042/BST20140321.

PMID:
25849928
5.

Stem cell hype: media portrayal of therapy translation.

Kamenova K, Caulfield T.

Sci Transl Med. 2015 Mar 11;7(278):278ps4. doi: 10.1126/scitranslmed.3010496. Review.

PMID:
25761887
6.

Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells.

Chitta K, Paulus A, Akhtar S, Blake MK, Caulfield TR, Novak AJ, Ansell SM, Advani P, Ailawadhi S, Sher T, Linder S, Chanan-Khan A.

Br J Haematol. 2015 May;169(3):377-90. doi: 10.1111/bjh.13304. Epub 2015 Feb 17.

PMID:
25691154
7.

Left ventricular assist device outflow cannula obstruction treated with percutaneous endovascular stenting.

Abraham J, Remick JD, Caulfield T, Puhlman M, Evenson K, Ott G, Kirker E.

Circ Heart Fail. 2015 Jan;8(1):229-30. doi: 10.1161/CIRCHEARTFAILURE.114.001891. No abstract available.

PMID:
25605641
8.

Representations of the health value of vitamin D supplementation in newspapers: media content analysis.

Caulfield T, Clark MI, McCormack JP, Rachul C, Field CJ.

BMJ Open. 2014 Dec 31;4(12):e006395. doi: 10.1136/bmjopen-2014-006395.

9.

Research ethics and stem cells: Is it time to re-think current approaches to oversight?

Caulfield T, Kamenova K, Ogbogu U, Zarzeczny A, Baltz J, Benjaminy S, Cassar PA, Clark M, Isasi R, Knoppers B, Knowles L, Korbutt G, Lavery JV, Lomax GP, Master Z, McDonald M, Preto N, Toews M.

EMBO Rep. 2015 Jan;16(1):2-6. doi: 10.15252/embr.201439819. Epub 2014 Dec 4. No abstract available.

PMID:
25476708
10.

Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia.

Chitta K, Paulus A, Caulfield TR, Akhtar S, Blake MK, Ailawadhi S, Knight J, Heckman MG, Pinkerton A, Chanan-Khan A.

Blood Cancer J. 2014 Nov 7;4:e260. doi: 10.1038/bcj.2014.74.

PMID:
25382610
11.

Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin.

Caulfield TR, Fiesel FC, Moussaud-Lamodière EL, Dourado DF, Flores SC, Springer W.

PLoS Comput Biol. 2014 Nov 6;10(11):e1003935. doi: 10.1371/journal.pcbi.1003935. eCollection 2014 Nov.

12.

Physician liability and non-invasive prenatal testing.

Toews M, Caulfield T.

J Obstet Gynaecol Can. 2014 Oct;36(10):907-14.

PMID:
25375305
13.

Professional regulation: a potentially valuable tool in responding to "stem cell tourism".

Zarzeczny A, Caulfield T, Ogbogu U, Bell P, Crooks VA, Kamenova K, Master Z, Rachul C, Snyder J, Toews M, Zoeller S.

Stem Cell Reports. 2014 Sep 9;3(3):379-84. doi: 10.1016/j.stemcr.2014.06.016. Epub 2014 Jul 31.

14.

Stem cell tourism and public education: the missing elements.

Master Z, Robertson K, Frederick D, Rachul C, Caulfield T.

Cell Stem Cell. 2014 Sep 4;15(3):267-70. doi: 10.1016/j.stem.2014.08.009.

PMID:
25192461
15.

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.

Zhang YJ, Jansen-West K, Xu YF, Gendron TF, Bieniek KF, Lin WL, Sasaguri H, Caulfield T, Hubbard J, Daughrity L, Chew J, Belzil VV, Prudencio M, Stankowski JN, Castanedes-Casey M, Whitelaw E, Ash PE, DeTure M, Rademakers R, Boylan KB, Dickson DW, Petrucelli L.

Acta Neuropathol. 2014 Oct;128(4):505-24. doi: 10.1007/s00401-014-1336-5. Epub 2014 Aug 31.

16.

Newspaper coverage of biobanks.

Ogbogu U, Toews M, Ollenberger A, Borry P, Nobile H, Bergmann M, Caulfield T.

PeerJ. 2014 Jul 31;2:e500. doi: 10.7717/peerj.500. eCollection 2014.

17.

Scientists' perspectives on consent in the context of biobanking research.

Master Z, Campo-Engelstein L, Caulfield T.

Eur J Hum Genet. 2015 May;23(5):569-74. doi: 10.1038/ejhg.2014.143. Epub 2014 Jul 30.

PMID:
25074466
18.

Defining 'medical necessity' in an age of personalised medicine: A view from Canada.

Caulfield T, Zarzeczny A.

Bioessays. 2014 Sep;36(9):813-7. doi: 10.1002/bies.201400073. Epub 2014 Jul 24.

PMID:
25059840
19.

Representations of stem cell clinics on Twitter.

Kamenova K, Reshef A, Caulfield T.

Stem Cell Rev. 2014 Dec;10(6):753-60. doi: 10.1007/s12015-014-9534-z.

PMID:
24970380
20.

Industry involvement in publicly funded biobanks.

Caulfield T, Borry P, Gottweis H.

Nat Rev Genet. 2014 Apr;15(4):220. doi: 10.1038/nrg3704. No abstract available.

PMID:
24772494
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