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Items: 1 to 20 of 480

1.

Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs.

Tang L, El-Din TM, Swanson TM, Pryde DC, Scheuer T, Zheng N, Catterall WA.

Nature. 2016 Aug 24. doi: 10.1038/nature19102. [Epub ahead of print]

PMID:
27556947
2.

KATP channel gain-of-function leads to increased myocardial L-type Ca2+ current and contractility in Cantu syndrome.

Levin MD, Singh GK, Zhang HX, Uchida K, Kozel BA, Stein PK, Kovacs A, Westenbroek RE, Catterall WA, Grange DK, Nichols CG.

Proc Natl Acad Sci U S A. 2016 Jun 14;113(24):6773-8. doi: 10.1073/pnas.1606465113. Epub 2016 May 31.

PMID:
27247394
3.

Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.

Patriarchi T, Qian H, Di Biase V, Malik ZA, Chowdhury D, Price JL, Hammes EA, Buonarati OR, Westenbroek RE, Catterall WA, Hofmann F, Xiang YK, Murphy GG, Chen CY, Navedo MF, Hell JW.

EMBO J. 2016 Jun 15;35(12):1330-45. doi: 10.15252/embj.201593409. Epub 2016 Apr 21.

PMID:
27103070
4.

Calcium sensor regulation of the CaV2.1 Ca2+ channel contributes to short-term synaptic plasticity in hippocampal neurons.

Nanou E, Sullivan JM, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1062-7. doi: 10.1073/pnas.1524636113. Epub 2016 Jan 11.

5.

Altered short-term synaptic plasticity and reduced muscle strength in mice with impaired regulation of presynaptic CaV2.1 Ca2+ channels.

Nanou E, Yan J, Whitehead NP, Kim MJ, Froehner SC, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1068-73. doi: 10.1073/pnas.1524650113. Epub 2016 Jan 11.

6.

The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels.

Alexander SP, Catterall WA, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2015 Dec;172(24):5904-41. doi: 10.1111/bph.13349.

PMID:
26650441
7.

The Concise Guide to PHARMACOLOGY 2015/16: Overview.

Alexander SP, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA; CGTP Collaborators.

Br J Pharmacol. 2015 Dec;172(24):5729-43. doi: 10.1111/bph.13347.

8.

The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands.

Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SP, Buneman OP, Davenport AP, McGrath JC, Peters JA, Spedding M, Catterall WA, Fabbro D, Davies JA; NC-IUPHAR.

Nucleic Acids Res. 2016 Jan 4;44(D1):D1054-68. doi: 10.1093/nar/gkv1037. Epub 2015 Oct 12.

9.

Finding Channels.

Catterall WA.

J Biol Chem. 2015 Nov 20;290(47):28357-73. doi: 10.1074/jbc.X115.683383. Epub 2015 Oct 2. No abstract available.

PMID:
26432640
10.

Phosphorylation sites in the Hook domain of CaVβ subunits differentially modulate CaV1.2 channel function.

Brunet S, Emrick MA, Sadilek M, Scheuer T, Catterall WA.

J Mol Cell Cardiol. 2015 Oct;87:248-56. doi: 10.1016/j.yjmcc.2015.08.006. Epub 2015 Aug 10.

PMID:
26271711
11.

Deciphering voltage-gated Na(+) and Ca(2+) channels by studying prokaryotic ancestors.

Catterall WA, Zheng N.

Trends Biochem Sci. 2015 Sep;40(9):526-34. doi: 10.1016/j.tibs.2015.07.002. Epub 2015 Aug 5. Review.

PMID:
26254514
12.

Dissecting the phenotypes of Dravet syndrome by gene deletion.

Rubinstein M, Han S, Tai C, Westenbroek RE, Hunker A, Scheuer T, Catterall WA.

Brain. 2015 Aug;138(Pt 8):2219-33. doi: 10.1093/brain/awv142. Epub 2015 May 27.

13.

Regulation of Cardiac Calcium Channels in the Fight-or-Flight Response.

Catterall WA.

Curr Mol Pharmacol. 2015;8(1):12-21. Review.

14.

The First 50 Years of Molecular Pharmacology.

Brown JH, Catterall WA, Conn PJ, Cull-Candy SG, Dingledine R, Harden TK, Insel PA, Milligan G, Traynelis SF.

Mol Pharmacol. 2015 Jul;88(1):139-40. doi: 10.1124/mol.115.099564. Epub 2015 May 5. Review.

15.

Structural Basis for Pharmacology of Voltage-Gated Sodium and Calcium Channels.

Catterall WA, Swanson TM.

Mol Pharmacol. 2015 Jul;88(1):141-50. doi: 10.1124/mol.114.097659. Epub 2015 Apr 6. Review.

16.

Na+ channel function, regulation, structure, trafficking and sequestration.

Chen-Izu Y, Shaw RM, Pitt GS, Yarov-Yarovoy V, Sack JT, Abriel H, Aldrich RW, Belardinelli L, Cannell MB, Catterall WA, Chazin WJ, Chiamvimonvat N, Deschenes I, Grandi E, Hund TJ, Izu LT, Maier LS, Maltsev VA, Marionneau C, Mohler PJ, Rajamani S, Rasmusson RL, Sobie EA, Clancy CE, Bers DM.

J Physiol. 2015 Mar 15;593(6):1347-60. doi: 10.1113/jphysiol.2014.281428. Review.

17.

Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.

Kalume F, Oakley JC, Westenbroek RE, Gile J, de la Iglesia HO, Scheuer T, Catterall WA.

Neurobiol Dis. 2015 May;77:141-54. doi: 10.1016/j.nbd.2015.02.016. Epub 2015 Mar 10.

18.

Modulation of CaV2.1 channels by neuronal calcium sensor-1 induces short-term synaptic facilitation.

Yan J, Leal K, Magupalli VG, Nanou E, Martinez GQ, Scheuer T, Catterall WA.

Mol Cell Neurosci. 2014 Nov;63:124-31.

19.

Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700.

Fu Y, Westenbroek RE, Scheuer T, Catterall WA.

Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16598-603. doi: 10.1073/pnas.1419129111. Epub 2014 Nov 3.

20.

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.

Rubinstein M, Westenbroek RE, Yu FH, Jones CJ, Scheuer T, Catterall WA.

Neurobiol Dis. 2015 Jan;73:106-17. doi: 10.1016/j.nbd.2014.09.017. Epub 2014 Oct 2.

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