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Results: 14


Intratumoral injection of IFN-alpha dendritic cells after dacarbazine activates anti-tumor immunity: results from a phase I trial in advanced melanoma.

Rozera C, Cappellini GA, D'Agostino G, Santodonato L, Castiello L, Urbani F, Macchia I, Aricò E, Casorelli I, Sestili P, Montefiore E, Monque D, Carlei D, Napolitano M, Rizza P, Moschella F, Buccione C, Belli R, Proietti E, Pavan A, Marchetti P, Belardelli F, Capone I.

J Transl Med. 2015 May 2;13:139. doi: 10.1186/s12967-015-0473-5.


Human bone marrow stromal cell confluence: effects on cell characteristics and methods of assessment.

Ren J, Wang H, Tran K, Civini S, Jin P, Castiello L, Feng J, Kuznetsov SA, Robey PG, Sabatino M, Stroncek DF.

Cytotherapy. 2015 Jul;17(7):897-911. doi: 10.1016/j.jcyt.2015.03.607. Epub 2015 Apr 14.


Leukemia cells induce changes in human bone marrow stromal cells.

Civini S, Jin P, Ren J, Sabatino M, Castiello L, Jin J, Wang H, Zhao Y, Marincola F, Stroncek D.

J Transl Med. 2013 Dec 4;11:298. doi: 10.1186/1479-5876-11-298.


Simplified process for the production of anti-CD19-CAR-engineered T cells.

Tumaini B, Lee DW, Lin T, Castiello L, Stroncek DF, Mackall C, Wayne A, Sabatino M.

Cytotherapy. 2013 Nov;15(11):1406-15. doi: 10.1016/j.jcyt.2013.06.003. Epub 2013 Aug 28.


Intra-subject variability in human bone marrow stromal cell (BMSC) replicative senescence: molecular changes associated with BMSC senescence.

Ren J, Stroncek DF, Zhao Y, Jin P, Castiello L, Civini S, Wang H, Feng J, Tran K, Kuznetsov SA, Robey PG, Sabatino M.

Stem Cell Res. 2013 Nov;11(3):1060-73. doi: 10.1016/j.scr.2013.07.005. Epub 2013 Jul 27.


Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation.

Fowler DH, Mossoba ME, Steinberg SM, Halverson DC, Stroncek D, Khuu HM, Hakim FT, Castiello L, Sabatino M, Leitman SF, Mariotti J, Gea-Banacloche JC, Sportes C, Hardy NM, Hickstein DD, Pavletic SZ, Rowley S, Goy A, Donato M, Korngold R, Pecora A, Levine BL, June CH, Gress RE, Bishop MR.

Blood. 2013 Apr 11;121(15):2864-74. doi: 10.1182/blood-2012-08-446872. Epub 2013 Feb 20.


Differential gene expression profile of first-generation and second-generation rapamycin-resistant allogeneic T cells.

Castiello L, Mossoba M, Viterbo A, Sabatino M, Fellowes V, Foley JE, Winterton M, Halverson DC, Civini S, Jin P, Fowler DH, Stroncek DF.

Cytotherapy. 2013 May;15(5):598-609. doi: 10.1016/j.jcyt.2012.12.008. Epub 2013 Jan 24.


Quality controls in cellular immunotherapies: rapid assessment of clinical grade dendritic cells by gene expression profiling.

Castiello L, Sabatino M, Zhao Y, Tumaini B, Ren J, Ping J, Wang E, Wood LV, Marincola FM, Puri RK, Stroncek DF.

Mol Ther. 2013 Feb;21(2):476-84. doi: 10.1038/mt.2012.89. Epub 2012 Nov 13. Erratum in: Mol Ther. 2013 Feb;21(2):495.


15 kDa granulysin causes differentiation of monocytes to dendritic cells but lacks cytotoxic activity.

Clayberger C, Finn MW, Wang T, Saini R, Wilson C, Barr VA, Sabatino M, Castiello L, Stroncek D, Krensky AM.

J Immunol. 2012 Jun 15;188(12):6119-26. doi: 10.4049/jimmunol.1200570. Epub 2012 May 14.


Concomitant detection of IFNα signature and activated monocyte/dendritic cell precursors in the peripheral blood of IFNα-treated subjects at early times after repeated local cytokine treatments.

Aricò E, Castiello L, Urbani F, Rizza P, Panelli MC, Wang E, Marincola FM, Belardelli F.

J Transl Med. 2011 May 17;9:67. doi: 10.1186/1479-5876-9-67.


15 kDa Granulysin versus GM-CSF for monocytes differentiation: analogies and differences at the transcriptome level.

Castiello L, Stroncek DF, Finn MW, Wang E, Marincola FM, Clayberger C, Krensky AM, Sabatino M.

J Transl Med. 2011 Apr 18;9:41. doi: 10.1186/1479-5876-9-41.


Monocyte-derived DC maturation strategies and related pathways: a transcriptional view.

Castiello L, Sabatino M, Jin P, Clayberger C, Marincola FM, Krensky AM, Stroncek DF.

Cancer Immunol Immunother. 2011 Apr;60(4):457-66. doi: 10.1007/s00262-010-0954-6. Epub 2011 Jan 22. Review.


Quality assessment of cellular therapies: the emerging role of molecular assays.

Stroncek DF, Jin P, Ren J, Feng J, Castiello L, Civini S, Wang E, Marincola FM, Sabatino M.

Korean J Hematol. 2010 Mar;45(1):14-22. doi: 10.5045/kjh.2010.45.1.14. Epub 2010 Mar 31.


Activation of TNF receptor 2 in microglia promotes induction of anti-inflammatory pathways.

Veroni C, Gabriele L, Canini I, Castiello L, Coccia E, Remoli ME, Columba-Cabezas S, Aricò E, Aloisi F, Agresti C.

Mol Cell Neurosci. 2010 Nov;45(3):234-44. doi: 10.1016/j.mcn.2010.06.014. Epub 2010 Jun 28.

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