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Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?

van Loon EP, Little R, Prehar S, Bindels RJ, Cartwright EJ, Hoenderop JG.

PLoS One. 2016 Apr 21;11(4):e0153483. doi: 10.1371/journal.pone.0153483. eCollection 2016.


Reconstructing transmission trees for communicable diseases using densely sampled genetic data.

Worby CJ, O'Neill PD, Kypraios T, Robotham JV, De Angelis D, Cartwright EJ, Peacock SJ, Cooper BS.

Ann Appl Stat. 2016 Mar;10(1):395-417. Epub 2016 Mar 25.


The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophy.

Mohamed TM, Abou-Leisa R, Stafford N, Maqsood A, Zi M, Prehar S, Baudoin-Stanley F, Wang X, Neyses L, Cartwright EJ, Oceandy D.

Nat Commun. 2016 Mar 29;7:11074. doi: 10.1038/ncomms11074.


Plasma membrane calcium ATPases (PMCAs) as potential targets for the treatment of essential hypertension.

Little R, Cartwright EJ, Neyses L, Austin C.

Pharmacol Ther. 2016 Mar;159:23-34. doi: 10.1016/j.pharmthera.2016.01.013. Epub 2016 Jan 25. Review.


Circulating Histone Concentrations Differentially Affect the Predominance of Left or Right Ventricular Dysfunction in Critical Illness.

Alhamdi Y, Zi M, Abrams ST, Liu T, Su D, Welters I, Dutt T, Cartwright EJ, Wang G, Toh CH.

Crit Care Med. 2016 May;44(5):e278-88. doi: 10.1097/CCM.0000000000001413.


Smad3 Couples Pak1 With the Antihypertrophic Pathway Through the E3 Ubiquitin Ligase, Fbxo32.

Tsui H, Zi M, Wang S, Chowdhury SK, Prehar S, Liang Q, Cartwright EJ, Lei M, Liu W, Wang X.

Hypertension. 2015 Dec;66(6):1176-83. doi: 10.1161/HYPERTENSIONAHA.115.06068. Epub 2015 Oct 19.


Deletion of the intestinal plasma membrane calcium pump, isoform 1, Atp2b1, in mice is associated with decreased bone mineral density and impaired responsiveness to 1, 25-dihydroxyvitamin D3.

Ryan ZC, Craig TA, Filoteo AG, Westendorf JJ, Cartwright EJ, Neyses L, Strehler EE, Kumar R.

Biochem Biophys Res Commun. 2015 Nov 6;467(1):152-6. doi: 10.1016/j.bbrc.2015.09.087. Epub 2015 Sep 21.


Hepatitis B Virus Reactivation During Successful Treatment of Hepatitis C Virus With Sofosbuvir and Simeprevir.

Collins JM, Raphael KL, Terry C, Cartwright EJ, Pillai A, Anania FA, Farley MM.

Clin Infect Dis. 2015 Oct 15;61(8):1304-6. doi: 10.1093/cid/civ474. Epub 2015 Jun 16.


Impact of routine bedside infectious disease consultation on clinical management and outcome of Staphylococcus aureus bacteraemia in adults.

Saunderson RB, Gouliouris T, Nickerson EK, Cartwright EJ, Kidney A, Aliyu SH, Brown NM, Limmathurotsakul D, Peacock SJ, Török ME.

Clin Microbiol Infect. 2015 Aug;21(8):779-85. doi: 10.1016/j.cmi.2015.05.026. Epub 2015 May 29.


A Multistate Investigation of Antibiotic-Resistant Salmonella enterica Serotype I 4,[5],12:i:- Infections as Part of an International Outbreak Associated with Frozen Feeder Rodents.

Cartwright EJ, Nguyen T, Melluso C, Ayers T, Lane C, Hodges A, Li X, Quammen J, Yendell SJ, Adams J, Mitchell J, Rickert R, Klos R, Williams IT, Barton Behravesh C, Wright J.

Zoonoses Public Health. 2016 Feb;63(1):62-71. doi: 10.1111/zph.12205. Epub 2015 May 21.


Emergent and evolving antimicrobial resistance cassettes in community-associated fusidic acid and meticillin-resistant Staphylococcus aureus.

Ellington MJ, Reuter S, Harris SR, Holden MT, Cartwright EJ, Greaves D, Gerver SM, Hope R, Brown NM, Török ME, Parkhill J, Köser CU, Peacock SJ.

Int J Antimicrob Agents. 2015 May;45(5):477-84. doi: 10.1016/j.ijantimicag.2015.01.009. Epub 2015 Feb 19.


Macitentan treatment retards the progression of established pulmonary arterial hypertension in an animal model.

Temple IP, Monfredi O, Quigley G, Schneider H, Zi M, Cartwright EJ, Boyett MR, Mahadevan VS, Hart G.

Int J Cardiol. 2014 Dec 15;177(2):423-8. doi: 10.1016/j.ijcard.2014.09.005. Epub 2014 Oct 11.


Pak1 is required to maintain ventricular Ca²⁺ homeostasis and electrophysiological stability through SERCA2a regulation in mice.

Wang Y, Tsui H, Ke Y, Shi Y, Li Y, Davies L, Cartwright EJ, Venetucci L, Zhang H, Terrar DA, Huang CL, Solaro RJ, Wang X, Lei M.

Circ Arrhythm Electrophysiol. 2014 Oct;7(5):938-48. doi: 10.1161/CIRCEP.113.001198. Epub 2014 Sep 12.


Plasma membrane calcium ATPase isoform 4 inhibits vascular endothelial growth factor-mediated angiogenesis through interaction with calcineurin.

Baggott RR, Alfranca A, López-Maderuelo D, Mohamed TM, Escolano A, Oller J, Ornes BC, Kurusamy S, Rowther FB, Brown JE, Oceandy D, Cartwright EJ, Wang W, Gómez-del Arco P, Martínez-Martínez S, Neyses L, Redondo JM, Armesilla AL.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2310-20. doi: 10.1161/ATVBAHA.114.304363. Epub 2014 Aug 21.


The mammalian Ste20-like kinase 2 (Mst2) modulates stress-induced cardiac hypertrophy.

Zi M, Maqsood A, Prehar S, Mohamed TM, Abou-Leisa R, Robertson A, Cartwright EJ, Ray SG, Oh S, Lim DS, Neyses L, Oceandy D.

J Biol Chem. 2014 Aug 29;289(35):24275-88. doi: 10.1074/jbc.M114.562405. Epub 2014 Jul 17.


Hepatitis C virus screening practices and seropositivity among US veterans born during 1945 - 1965.

Cartwright EJ, Rentsch C, Rimland D.

BMC Res Notes. 2014 Jul 14;7:449. doi: 10.1186/1756-0500-7-449.


Impact of infectious diseases consultation on the management of Staphylococcus aureus bacteraemia in children.

Saunderson RB, Gouliouris T, Cartwright EJ, Nickerson EJ, Aliyu SH, O'Donnell DR, Kelsall W, Limmathurotsakul D, Peacock SJ, Török ME.

BMJ Open. 2014 Jul 1;4(7):e004659. doi: 10.1136/bmjopen-2013-004659.


Zero tolerance for healthcare-associated MRSA bacteraemia: is it realistic?

Török ME, Harris SR, Cartwright EJ, Raven KE, Brown NM, Allison ME, Greaves D, Quail MA, Limmathurotsakul D, Holden MT, Parkhill J, Peacock SJ.

J Antimicrob Chemother. 2014 Aug;69(8):2238-45. doi: 10.1093/jac/dku128. Epub 2014 Apr 30.


The tumour suppressor Ras-association domain family protein 1A (RASSF1A) regulates TNF-α signalling in cardiomyocytes.

Mohamed TM, Zi M, Prehar S, Maqsood A, Abou-Leisa R, Nguyen L, Pfeifer GP, Cartwright EJ, Neyses L, Oceandy D.

Cardiovasc Res. 2014 Jul 1;103(1):47-59. doi: 10.1093/cvr/cvu111. Epub 2014 Apr 28.


Mkk4 is a negative regulator of the transforming growth factor beta 1 signaling associated with atrial remodeling and arrhythmogenesis with age.

Davies L, Jin J, Shen W, Tsui H, Shi Y, Wang Y, Zhang Y, Hao G, Wu J, Chen S, Fraser JA, Dong N, Christoffels V, Ravens U, Huang CL, Zhang H, Cartwright EJ, Wang X, Lei M.

J Am Heart Assoc. 2014 Apr 10;3(2):e000340. doi: 10.1161/JAHA.113.000340.

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