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Results: 1 to 20 of 216

1.

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.

Parnas O, Jovanovic M, Eisenhaure TM, Herbst RH, Dixit A, Ye CJ, Przybylski D, Platt RJ, Tirosh I, Sanjana NE, Shalem O, Satija R, Raychowdhury R, Mertins P, Carr SA, Zhang F, Hacohen N, Regev A.

Cell. 2015 Jul 15. pii: S0092-8674(15)00829-6. doi: 10.1016/j.cell.2015.06.059. [Epub ahead of print]

PMID:
26189680
2.

The Extracellular Matrix: Tools and Insights for the "Omics" Era.

Naba A, Clauser KR, Ding H, Whittaker CA, Carr SA, Hynes RO.

Matrix Biol. 2015 Jul 7. pii: S0945-053X(15)00121-3. doi: 10.1016/j.matbio.2015.06.003. [Epub ahead of print] Review.

3.

Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis.

Kroksveen AC, Jaffe JD, Aasebø E, Barsnes H, Bjørlykke Y, Franciotta D, Keshishian H, Myhr KM, Opsahl JA, van Pesch V, Teunissen CE, Torkildsen Ø, Ulvik RJ, Vethe H, Carr SA, Berven FS.

Proteomics. 2015 Jul 7. doi: 10.1002/pmic.201400142. [Epub ahead of print]

PMID:
26152395
4.

Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.

Krönke J, Fink EC, Hollenbach PW, MacBeth KJ, Hurst SN, Udeshi ND, Chamberlain PP, Mani DR, Man HW, Gandhi AK, Svinkina T, Schneider RK, McConkey M, Järås M, Griffiths E, Wetzler M, Bullinger L, Cathers BE, Carr SA, Chopra R, Ebert BL.

Nature. 2015 Jul 9;523(7559):183-8. doi: 10.1038/nature14610. Epub 2015 Jul 1.

PMID:
26131937
5.

Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.

Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ.

Cell Rep. 2015 Jun 30;11(12):1905-18. doi: 10.1016/j.celrep.2015.05.045. Epub 2015 Jun 18.

6.

Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.

Chou DH, Vetere A, Choudhary A, Scully SS, Schenone M, Tang A, Gomez R, Burns SM, Lundh M, Vital T, Comer E, Faloon PW, Dančík V, Ciarlo C, Paulk J, Dai M, Reddy C, Sun H, Young M, Donato N, Jaffe J, Clemons PA, Palmer M, Carr SA, Schreiber SL, Wagner BK.

J Am Chem Soc. 2015 Jun 24;137(24):7929-34. doi: 10.1021/jacs.5b04284. Epub 2015 Jun 15.

PMID:
26042473
7.

On Credibility, Clarity, and Compliance.

Burlingame A, Carr SA, Bradshaw RA, Chalkley RJ.

Mol Cell Proteomics. 2015 Jul;14(7):1731-3. doi: 10.1074/mcp.E115.052506. Epub 2015 Jun 3. No abstract available.

PMID:
26041845
8.

Antibody-based capture of target peptides in multiple reaction monitoring experiments.

De Marchi T, Kuhn E, Carr SA, Umar A.

Methods Mol Biol. 2015;1293:123-35. doi: 10.1007/978-1-4939-2519-3_7.

PMID:
26040685
9.

Deep, quantitative coverage of the lysine acetylome using novel anti-acetyl-lysine antibodies and an optimized proteomic workflow.

Svinkina T, Gu H, Silva JC, Mertins P, Qiao J, Fereshetian S, Jaffe JD, Kuhn E, Udeshi ND, Carr SA.

Mol Cell Proteomics. 2015 May 7. pii: mcp.O114.047555. [Epub ahead of print]

10.

Immunogenetics. Dynamic profiling of the protein life cycle in response to pathogens.

Jovanovic M, Rooney MS, Mertins P, Przybylski D, Chevrier N, Satija R, Rodriguez EH, Fields AP, Schwartz S, Raychowdhury R, Mumbach MR, Eisenhaure T, Rabani M, Gennert D, Lu D, Delorey T, Weissman JS, Carr SA, Hacohen N, Regev A.

Science. 2015 Mar 6;347(6226):1259038. doi: 10.1126/science.1259038. Epub 2015 Feb 12.

PMID:
25745177
11.

Multiplexed, Quantitative Workflow for Sensitive Biomarker Discovery in Plasma Yields Novel Candidates for Early Myocardial Injury.

Keshishian H, Burgess MW, Gillette MA, Mertins P, Clauser KR, Mani DR, Kuhn EW, Farrell LA, Gerszten RE, Carr SA.

Mol Cell Proteomics. 2015 Feb 27. pii: mcp.M114.046813. [Epub ahead of print]

12.

Large-scale inter-laboratory study to develop, analytically validate and apply highly multiplexed, quantitative peptide assays to measure cancer-relevant proteins in plasma.

Abbatiello SE, Schilling B, Mani DR, Zimmerman LJ, Hall SC, MacLean B, Albertolle M, Allen S, Burgess M, Cusack MP, Ghosh M, Hedrick V, Held JM, Inerowicz HD, Jackson A, Keshishian H, Kinsinger CR, Lyssand J, Makowski L, Mesri M, Rodriguez H, Rudnick P, Sadowski P, Sedransk N, Shaddox K, Skates SJ, Kuhn E, Smith D, Whiteaker JR, Whitwell C, Zhang S, Borchers CH, Fisher SJ, Gibson BW, Liebler DC, MacCoss MJ, Neubert TA, Paulovich AG, Regnier FE, Tempst P, Carr SA.

Mol Cell Proteomics. 2015 Feb 18. pii: mcp.M114.047050. [Epub ahead of print]

13.

Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator.

Maier VK, Feeney CM, Taylor JE, Creech AL, Qiao JW, Szanto A, Das PP, Chevrier N, Cifuentes-Rojas C, Orkin SH, Carr SA, Jaffe JD, Mertins P, Lee JT.

Mol Cell Proteomics. 2015 Jun;14(6):1435-46. doi: 10.1074/mcp.M114.044586. Epub 2015 Feb 13.

PMID:
25680957
14.

Occurrence of halogenated transformation products of selected pharmaceuticals and personal care products in secondary and tertiary treated wastewaters from southern California.

Bulloch DN, Nelson ED, Carr SA, Wissman CR, Armstrong JL, Schlenk D, Larive CK.

Environ Sci Technol. 2015 Feb 17;49(4):2044-51. doi: 10.1021/es504565n. Epub 2015 Feb 5.

PMID:
25611547
15.

CDK5 is a major regulator of the tumor suppressor DLC1.

Tripathi BK, Qian X, Mertins P, Wang D, Papageorge AG, Carr SA, Lowy DR.

J Cell Biol. 2014 Dec 8;207(5):627-42. doi: 10.1083/jcb.201405105. Epub 2014 Dec 1.

16.

Building the Connectivity Map of epigenetics: chromatin profiling by quantitative targeted mass spectrometry.

Creech AL, Taylor JE, Maier VK, Wu X, Feeney CM, Udeshi ND, Peach SE, Boehm JS, Lee JT, Carr SA, Jaffe JD.

Methods. 2015 Jan 15;72:57-64. doi: 10.1016/j.ymeth.2014.10.033. Epub 2014 Nov 6.

PMID:
25448295
17.

Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.

Theurillat JP, Udeshi ND, Errington WJ, Svinkina T, Baca SC, Pop M, Wild PJ, Blattner M, Groner AC, Rubin MA, Moch H, Privé GG, Carr SA, Garraway LA.

Science. 2014 Oct 3;346(6205):85-9. doi: 10.1126/science.1250255. Epub 2014 Oct 2.

18.

Overview of Peptide and protein analysis by mass spectrometry.

Zhang G, Annan RS, Carr SA, Neubert TA.

Curr Protoc Mol Biol. 2014 Oct 1;108:10.21.1-10.21.30. doi: 10.1002/0471142727.mb1021s108.

PMID:
25271712
19.

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.

Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhardt F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA.

Nat Cell Biol. 2014 Nov;16(11):1105-17. doi: 10.1038/ncb3041. Epub 2014 Sep 28.

20.

Panorama: a targeted proteomics knowledge base.

Sharma V, Eckels J, Taylor GK, Shulman NJ, Stergachis AB, Joyner SA, Yan P, Whiteaker JR, Halusa GN, Schilling B, Gibson BW, Colangelo CM, Paulovich AG, Carr SA, Jaffe JD, MacCoss MJ, MacLean B.

J Proteome Res. 2014 Sep 5;13(9):4205-10. doi: 10.1021/pr5006636. Epub 2014 Aug 18.

PMID:
25102069
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