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Items: 12


An ultra-deep sequencing strategy to detect sub-clonal TP53 mutations in presentation chronic lymphocytic leukaemia cases using multiple polymerases.

Worrillow L, Baskaran P, Care MA, Varghese A, Munir T, Evans PA, O'Connor SJ, Rawstron A, Hazelwood L, Tooze RM, Hillmen P, Newton DJ.

Oncogene. 2016 Apr 4. doi: 10.1038/onc.2016.73. [Epub ahead of print]


Transferring genomics to the clinic: distinguishing Burkitt and diffuse large B cell lymphomas.

Sha C, Barrans S, Care MA, Cunningham D, Tooze RM, Jack A, Westhead DR.

Genome Med. 2015 Jul 1;7(1):64. doi: 10.1186/s13073-015-0187-6. eCollection 2015.


SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity.

Care MA, Cocco M, Laye JP, Barnes N, Huang Y, Wang M, Barrans S, Du M, Jack A, Westhead DR, Doody GM, Tooze RM.

Nucleic Acids Res. 2014 Jul;42(12):7591-610. doi: 10.1093/nar/gku451. Epub 2014 May 29.


A microarray platform-independent classification tool for cell of origin class allows comparative analysis of gene expression in diffuse large B-cell lymphoma.

Care MA, Barrans S, Worrillow L, Jack A, Westhead DR, Tooze RM.

PLoS One. 2013;8(2):e55895. doi: 10.1371/journal.pone.0055895. Epub 2013 Feb 12.


In vitro generation of long-lived human plasma cells.

Cocco M, Stephenson S, Care MA, Newton D, Barnes NA, Davison A, Rawstron A, Westhead DR, Doody GM, Tooze RM.

J Immunol. 2012 Dec 15;189(12):5773-85. doi: 10.4049/jimmunol.1103720. Epub 2012 Nov 16.


Whole genome expression profiling based on paraffin embedded tissue can be used to classify diffuse large B-cell lymphoma and predict clinical outcome.

Barrans SL, Crouch S, Care MA, Worrillow L, Smith A, Patmore R, Westhead DR, Tooze R, Roman E, Jack AS.

Br J Haematol. 2012 Nov;159(4):441-53. doi: 10.1111/bjh.12045. Epub 2012 Sep 13.


An extended set of PRDM1/BLIMP1 target genes links binding motif type to dynamic repression.

Doody GM, Care MA, Burgoyne NJ, Bradford JR, Bota M, Bonifer C, Westhead DR, Tooze RM.

Nucleic Acids Res. 2010 Sep;38(16):5336-50. doi: 10.1093/nar/gkq268. Epub 2010 Apr 26.


GO-At: in silico prediction of gene function in Arabidopsis thaliana by combining heterogeneous data.

Bradford JR, Needham CJ, Tedder P, Care MA, Bulpitt AJ, Westhead DR.

Plant J. 2010 Feb;61(4):713-21. doi: 10.1111/j.1365-313X.2009.04097.x. Epub 2009 Nov 27.


Combining the interactome and deleterious SNP predictions to improve disease gene identification.

Care MA, Bradford JR, Needham CJ, Bulpitt AJ, Westhead DR.

Hum Mutat. 2009 Mar;30(3):485-92. doi: 10.1002/humu.20917.


Deleterious SNP prediction: be mindful of your training data!

Care MA, Needham CJ, Bulpitt AJ, Westhead DR.

Bioinformatics. 2007 Mar 15;23(6):664-72. Epub 2007 Jan 18.


Predicting the effect of missense mutations on protein function: analysis with Bayesian networks.

Needham CJ, Bradford JR, Bulpitt AJ, Care MA, Westhead DR.

BMC Bioinformatics. 2006 Sep 6;7:405.

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