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Results: 1 to 20 of 323

1.

Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.

Pineda M, González-Acosta M, Thompson BA, Sánchez R, Gómez C, Martínez-López J, Perea J, Caldés T, Rodríguez Y, Landolfi S, Balmaña J, Lázaro C, Robles L, Capellá G, Rueda D.

Clin Genet. 2014 Jul 25. doi: 10.1111/cge.12467. [Epub ahead of print]

PMID:
25060679
[PubMed - as supplied by publisher]
2.

The Ribonucleoprotein HNRNPA2B1 Interacts With and Regulates Oncogenic KRAS in Pancreatic Ductal Adenocarcinoma Cells.

Barceló C, Etchin J, Mansour MR, Sanda T, Ginesta MM, Sanchez-Arévalo Lobo VJ, Real FX, Capellà G, Estanyol JM, Jaumot M, Look AT, Agell N.

Gastroenterology. 2014 Jul 3. pii: S0016-5085(14)00852-X. doi: 10.1053/j.gastro.2014.06.041. [Epub ahead of print]

PMID:
24998203
[PubMed - as supplied by publisher]
3.

Little evidence for association between the TGFBR1*6A variant and colorectal cancer: a family-based association study on non-syndromic family members from Australia and Spain.

Ross JP, Lockett LJ, Tabor B, Saunders IW, Young GP, Macrae F, Blanco I, Capella G, Brown GS, Lockett TJ, Hannan GN.

BMC Cancer. 2014 Jul 1;14(1):475. doi: 10.1186/1471-2407-14-475.

PMID:
24981199
[PubMed - in process]
Free PMC Article
4.

Prevalence of germline MUTYH mutations among Lynch-like syndrome patients.

Castillejo A, Vargas G, Castillejo MI, Navarro M, Barberá VM, González S, Hernández-Illán E, Brunet J, Ramón Y Cajal T, Balmaña J, Oltra S, Iglesias S, Velasco A, Solanes A, Campos O, Sánchez Heras AB, Gallego J, Carrasco E, González Juan D, Segura A, Chirivella I, Juan MJ, Tena I, Lázaro C, Blanco I, Pineda M, Capellá G, Soto JL.

Eur J Cancer. 2014 Jun 18. pii: S0959-8049(14)00721-7. doi: 10.1016/j.ejca.2014.05.022. [Epub ahead of print]

PMID:
24953332
[PubMed - as supplied by publisher]
5.

Comprehensive molecular characterisation of hereditary non-polyposis colorectal tumours with mismatch repair proficiency.

Bellido F, Pineda M, Sanz-Pamplona R, Navarro M, Nadal M, Lázaro C, Blanco I, Moreno V, Capellá G, Valle L.

Eur J Cancer. 2014 Jul;50(11):1964-72. doi: 10.1016/j.ejca.2014.04.022. Epub 2014 May 16.

PMID:
24841217
[PubMed - in process]
6.

Exome sequencing identifies MUTYH mutations in a family with colorectal cancer and an atypical phenotype.

Seguí N, Navarro M, Pineda M, Köger N, Bellido F, González S, Campos O, Iglesias S, Valdés-Mas R, López-Doriga A, Gut M, Blanco I, Lázaro C, Capellá G, Puente XS, Plotz G, Valle L.

Gut. 2014 Apr 1. doi: 10.1136/gutjnl-2014-307084. [Epub ahead of print] No abstract available.

PMID:
24691292
[PubMed - as supplied by publisher]
7.

Genetic variants in the IL1A gene region contribute to intestinal-type gastric carcinoma susceptibility in European populations.

Durães C, Muñoz X, Bonet C, García N, Venceslá A, Carneiro F, Peleteiro B, Lunet N, Barros H, Lindkvist B, Boutron-Ruault MC, Bueno-de-Mesquita HB, Rizzato C, Trichopoulou A, Weiderpass E, Naccarati A, Travis RC, Tjønneland A, Gurrea AB, Johansson M, Riboli E, Figueiredo C, González CA, Capellà G, Machado JC, Sala N.

Int J Cancer. 2014 Sep 15;135(6):1343-55. doi: 10.1002/ijc.28776. Epub 2014 Mar 4.

PMID:
24615437
[PubMed - in process]
8.

New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis.

Valle L, Hernández-Illán E, Bellido F, Aiza G, Castillejo A, Castillejo MI, Navarro M, Seguí N, Vargas G, Guarinos C, Juarez M, Sanjuán X, Iglesias S, Alenda C, Egoavil C, Segura Á, Juan MJ, Rodriguez-Soler M, Brunet J, González S, Jover R, Lázaro C, Capellá G, Pineda M, Soto JL, Blanco I.

Hum Mol Genet. 2014 Jul 1;23(13):3506-12. doi: 10.1093/hmg/ddu058. Epub 2014 Feb 5.

PMID:
24501277
[PubMed - in process]
9.

Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.

Seguí N, Guinó E, Pineda M, Navarro M, Bellido F, Lázaro C, Blanco I, Moreno V, Capellá G, Valle L.

PLoS One. 2014 Feb 3;9(2):e86063. doi: 10.1371/journal.pone.0086063. eCollection 2014.

PMID:
24498269
[PubMed - in process]
Free PMC Article
10.

Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.

Barceló C, Paco N, Morell M, Alvarez-Moya B, Bota-Rabassedas N, Jaumot M, Vilardell F, Capella G, Agell N.

Cancer Res. 2014 Feb 15;74(4):1190-9. doi: 10.1158/0008-5472.CAN-13-1750. Epub 2013 Dec 26.

PMID:
24371225
[PubMed - indexed for MEDLINE]
11.

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.

Thompson BA, Spurdle AB, Plazzer JP, Greenblatt MS, Akagi K, Al-Mulla F, Bapat B, Bernstein I, Capellá G, den Dunnen JT, du Sart D, Fabre A, Farrell MP, Farrington SM, Frayling IM, Frebourg T, Goldgar DE, Heinen CD, Holinski-Feder E, Kohonen-Corish M, Robinson KL, Leung SY, Martins A, Moller P, Morak M, Nystrom M, Peltomaki P, Pineda M, Qi M, Ramesar R, Rasmussen LJ, Royer-Pokora B, Scott RJ, Sijmons R, Tavtigian SV, Tops CM, Weber T, Wijnen J, Woods MO, Macrae F, Genuardi M; InSiGHT.

Nat Genet. 2014 Feb;46(2):107-15. doi: 10.1038/ng.2854. Epub 2013 Dec 22.

PMID:
24362816
[PubMed - indexed for MEDLINE]
12.

ICO amplicon NGS data analysis: a Web tool for variant detection in common high-risk hereditary cancer genes analyzed by amplicon GS Junior next-generation sequencing.

Lopez-Doriga A, Feliubadaló L, Menéndez M, Lopez-Doriga S, Morón-Duran FD, del Valle J, Tornero E, Montes E, Cuesta R, Campos O, Gómez C, Pineda M, González S, Moreno V, Capellá G, Lázaro C.

Hum Mutat. 2014 Mar;35(3):271-7.

PMID:
24227591
[PubMed - in process]
13.

Epigenetic inactivation of microRNA-34b/c predicts poor disease-free survival in early-stage lung adenocarcinoma.

Nadal E, Chen G, Gallegos M, Lin L, Ferrer-Torres D, Truini A, Wang Z, Lin J, Reddy RM, Llatjos R, Escobar I, Moya J, Chang AC, Cardenal F, Capellà G, Beer DG.

Clin Cancer Res. 2013 Dec 15;19(24):6842-52. doi: 10.1158/1078-0432.CCR-13-0736. Epub 2013 Oct 15.

PMID:
24130071
[PubMed - in process]
14.

GALNT12 is not a major contributor of familial colorectal cancer type X.

Seguí N, Pineda M, Navarro M, Lázaro C, Brunet J, Infante M, Durán M, Soto JL, Blanco I, Capellá G, Valle L.

Hum Mutat. 2014 Jan;35(1):50-2. doi: 10.1002/humu.22454. Epub 2013 Oct 17.

PMID:
24115450
[PubMed - in process]
15.

Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial-to-mesenchymal transition.

Roepman P, Schlicker A, Tabernero J, Majewski I, Tian S, Moreno V, Snel MH, Chresta CM, Rosenberg R, Nitsche U, Macarulla T, Capella G, Salazar R, Orphanides G, Wessels LF, Bernards R, Simon IM.

Int J Cancer. 2014 Feb 1;134(3):552-62. doi: 10.1002/ijc.28387. Epub 2013 Sep 13.

PMID:
23852808
[PubMed - indexed for MEDLINE]
16.

Refining the role of PMS2 in Lynch syndrome: germline mutational analysis improved by comprehensive assessment of variants.

Borràs E, Pineda M, Cadiñanos J, Del Valle J, Brieger A, Hinrichsen I, Cabanillas R, Navarro M, Brunet J, Sanjuan X, Musulen E, van der Klift H, Lázaro C, Plotz G, Blanco I, Capellá G.

J Med Genet. 2013 Aug;50(8):552-63. doi: 10.1136/jmedgenet-2012-101511. Epub 2013 May 24.

PMID:
23709753
[PubMed - indexed for MEDLINE]
17.

DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer.

Carmona FJ, Azuara D, Berenguer-Llergo A, Fernández AF, Biondo S, de Oca J, Rodriguez-Moranta F, Salazar R, Villanueva A, Fraga MF, Guardiola J, Capellá G, Esteller M, Moreno V.

Cancer Prev Res (Phila). 2013 Jul;6(7):656-65. doi: 10.1158/1940-6207.CAPR-12-0501. Epub 2013 May 21.

PMID:
23694962
[PubMed - indexed for MEDLINE]
18.

Metronomic chemotherapy following the maximum tolerated dose is an effective anti-tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells.

Vives M, Ginestà MM, Gracova K, Graupera M, Casanovas O, Capellà G, Serrano T, Laquente B, Viñals F.

Int J Cancer. 2013 Nov 15;133(10):2464-72. doi: 10.1002/ijc.28259. Epub 2013 Jun 4.

PMID:
23649709
[PubMed - indexed for MEDLINE]
19.

Telomere length and genetic anticipation in Lynch syndrome.

Seguí N, Pineda M, Guinó E, Borràs E, Navarro M, Bellido F, Moreno V, Lázaro C, Blanco I, Capellá G, Valle L.

PLoS One. 2013 Apr 23;8(4):e61286. doi: 10.1371/journal.pone.0061286. Print 2013.

PMID:
23637804
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Grape antioxidant dietary fiber inhibits intestinal polyposis in ApcMin/+ mice: relation to cell cycle and immune response.

Sánchez-Tena S, Lizárraga D, Miranda A, Vinardell MP, García-García F, Dopazo J, Torres JL, Saura-Calixto F, Capellà G, Cascante M.

Carcinogenesis. 2013 Aug;34(8):1881-8. doi: 10.1093/carcin/bgt140. Epub 2013 Apr 24.

PMID:
23615403
[PubMed - indexed for MEDLINE]

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