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Results: 1 to 20 of 241


B cell expression of the SH2-containing inositol 5-phosphatase (SHIP-1) is required to establish anergy to high affinity, proteinacious autoantigens.

Akerlund J, Getahun A, Cambier JC.

J Autoimmun. 2015 Aug;62:45-54. doi: 10.1016/j.jaut.2015.06.007. Epub 2015 Jul 4.


γδ T cells affect IL-4 production and B-cell tolerance.

Huang Y, Heiser RA, Detanico TO, Getahun A, Kirchenbaum GA, Casper TL, Aydintug MK, Carding SR, Ikuta K, Huang H, Cambier JC, Wysocki LJ, O'Brien RL, Born WK.

Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):E39-48. doi: 10.1073/pnas.1415107111. Epub 2014 Dec 22.


Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production.

White MJ, McArthur K, Metcalf D, Lane RM, Cambier JC, Herold MJ, van Delft MF, Bedoui S, Lessene G, Ritchie ME, Huang DC, Kile BT.

Cell. 2014 Dec 18;159(7):1549-62. doi: 10.1016/j.cell.2014.11.036.


Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients.

Smith MJ, Packard TA, O'Neill SK, Henry Dunand CJ, Huang M, Fitzgerald-Miller L, Stowell D, Hinman RM, Wilson PC, Gottlieb PA, Cambier JC.

Diabetes. 2015 May;64(5):1703-12. doi: 10.2337/db13-1798. Epub 2014 Dec 18.


Role of B lymphocytes in the pathogenesis of type 1 diabetes.

Hinman RM, Cambier JC.

Curr Diab Rep. 2014;14(11):543. doi: 10.1007/s11892-014-0543-8. Review.


B cells and type 1 diabetes mice and men.

Hinman RM, Smith MJ, Cambier JC.

Immunol Lett. 2014 Aug;160(2):128-32. doi: 10.1016/j.imlet.2014.01.010. Epub 2014 Jan 25. Review.


Anti-CD79 antibody induces B cell anergy that protects against autoimmunity.

Hardy IR, Anceriz N, Rousseau F, Seefeldt MB, Hatterer E, Irla M, Buatois V, Chatel LE, Getahun A, Fletcher A, Cons L, Pontini G, Hertzberg NA, Magistrelli G, Malinge P, Smith MJ, Reith W, Kosco-Vilbois MH, Ferlin WG, Cambier JC.

J Immunol. 2014 Feb 15;192(4):1641-50. doi: 10.4049/jimmunol.1302672. Epub 2014 Jan 17.


B lymphocyte antigen receptor signaling: initiation, amplification, and regulation.

Packard TA, Cambier JC.

F1000Prime Rep. 2013 Oct 1;5:40. doi: 10.12703/P5-40. Review.


Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.

Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C.

EMBO Rep. 2013 Oct;14(10):900-6. doi: 10.1038/embor.2013.132. Epub 2013 Sep 6.


Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.

Bounab Y, Getahun A, Cambier JC, Daëron M.

Curr Opin Immunol. 2013 Jun;25(3):313-20. doi: 10.1016/j.coi.2013.04.001. Epub 2013 May 15. Review.


Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways.

Cambier JC.

J Clin Invest. 2013 May;123(5):1928-31. doi: 10.1172/JCI69289. Epub 2013 Apr 24.


STING/MPYS mediates host defense against Listeria monocytogenes infection by regulating Ly6C(hi) monocyte migration.

Jin L, Getahun A, Knowles HM, Mogan J, Akerlund LJ, Packard TA, Perraud AL, Cambier JC.

J Immunol. 2013 Mar 15;190(6):2835-43. doi: 10.4049/jimmunol.1201788. Epub 2013 Feb 1.


Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa.

Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, de Zoeten EF, Cambier JC, Stenmark KR, Colgan SP, Eltzschig HK.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):E2784-93. doi: 10.1073/pnas.1202366109. Epub 2012 Sep 17.


Integrated immunology in Colorado.

Slansky JE, Cohen JJ, Cambier JC.

Immunol Res. 2013 Mar;55(1-3):1-2. doi: 10.1007/s12026-012-8376-5. No abstract available.


COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.

Packard TA, Li QZ, Cosgrove GP, Bowler RP, Cambier JC.

Immunol Res. 2013 Mar;55(1-3):48-57. doi: 10.1007/s12026-012-8347-x.


Retention of anergy and inhibition of antibody responses during acute γ herpesvirus 68 infection.

Getahun A, Smith MJ, Kogut I, van Dyk LF, Cambier JC.

J Immunol. 2012 Sep 15;189(6):2965-74. doi: 10.4049/jimmunol.1201407. Epub 2012 Aug 17.


SMIP-016 in action: CD37 as a death receptor.

Jin L, Cambier JC.

Cancer Cell. 2012 May 15;21(5):597-8. doi: 10.1016/j.ccr.2012.04.034.


B cell maintenance and function in aging.

Kogut I, Scholz JL, Cancro MP, Cambier JC.

Semin Immunol. 2012 Oct;24(5):342-9. doi: 10.1016/j.smim.2012.04.004. Epub 2012 May 4. Review.


B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity.

Khalil AM, Cambier JC, Shlomchik MJ.

Science. 2012 Jun 1;336(6085):1178-81. doi: 10.1126/science.1213368. Epub 2012 May 3.


The inositol 5-phosphatase SHIP-1 and adaptors Dok-1 and 2 play central roles in CD4-mediated inhibitory signaling.

Waterman PM, Marschner S, Brandl E, Cambier JC.

Immunol Lett. 2012 Mar 30;143(1):122-30. doi: 10.1016/j.imlet.2012.02.009. Epub 2012 Feb 24.

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