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Results: 1 to 20 of 68


Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence.

Farrelly L, Föcking M, Piontkewitz Y, Dicker P, English J, Wynne K, Cannon M, Cagney G, Cotter DR.

Dev Neurosci. 2015;37(1):43-55. doi: 10.1159/000368305. Epub 2015 Jan 13.


Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia.

Föcking M, Lopez LM, English JA, Dicker P, Wolff A, Brindley E, Wynne K, Cagney G, Cotter DR.

Mol Psychiatry. 2015 Apr;20(4):424-32. doi: 10.1038/mp.2014.63. Epub 2014 Jul 22.


Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex.

Farrelly LA, Dicker P, Wynne K, English J, Cagney G, Föcking M, Cotter DR.

Proteomics. 2014 Jun;14(12):1574-8. doi: 10.1002/pmic.201300466. Epub 2014 May 16.


Targeted proteomics for validation of biomarkers in early psychosis.

English JA, Wynne K, Cagney G, Cotter DR.

Biol Psychiatry. 2014 Sep 15;76(6):e7-9. doi: 10.1016/j.biopsych.2013.11.016. Epub 2013 Nov 22. No abstract available.


Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus.

English JA, Harauma A, Föcking M, Wynne K, Scaife C, Cagney G, Moriguchi T, Cotter DR.

Front Genet. 2013 Oct 28;4:208. doi: 10.3389/fgene.2013.00208. eCollection 2013.


The effect of polyphosphate kinase gene deletion on polyhydroxyalkanoate accumulation and carbon metabolism in Pseudomonas putida KT2440.

Casey WT, Nikodinovic-Runic J, Fonseca Garcia P, Guzik MW, McGrath JW, Quinn JP, Cagney G, Prieto MA, O'Connor KE.

Environ Microbiol Rep. 2013 Oct;5(5):740-6. doi: 10.1111/1758-2229.12076. Epub 2013 Aug 18.


Invadolysin, a conserved lipid-droplet-associated metalloproteinase, is required for mitochondrial function in Drosophila.

Di Cara F, Duca E, Dunbar DR, Cagney G, Heck MM.

J Cell Sci. 2013 Oct 15;126(Pt 20):4769-81. doi: 10.1242/jcs.133306. Epub 2013 Aug 13.


All or nothing: protein complexes flip essentiality between distantly related eukaryotes.

Ryan CJ, Krogan NJ, Cunningham P, Cagney G.

Genome Biol Evol. 2013;5(6):1049-59. doi: 10.1093/gbe/evt074.


Quantitative genetic-interaction mapping in mammalian cells.

Roguev A, Talbot D, Negri GL, Shales M, Cagney G, Bandyopadhyay S, Panning B, Krogan NJ.

Nat Methods. 2013 May;10(5):432-7. doi: 10.1038/nmeth.2398. Epub 2013 Feb 13.


Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation.

Brien GL, Gambero G, O'Connell DJ, Jerman E, Turner SA, Egan CM, Dunne EJ, Jurgens MC, Wynne K, Piao L, Lohan AJ, Ferguson N, Shi X, Sinha KM, Loftus BJ, Cagney G, Bracken AP.

Nat Struct Mol Biol. 2012 Dec;19(12):1273-81. doi: 10.1038/nsmb.2449. Epub 2012 Nov 18.


Hierarchical modularity and the evolution of genetic interactomes across species.

Ryan CJ, Roguev A, Patrick K, Xu J, Jahari H, Tong Z, Beltrao P, Shales M, Qu H, Collins SR, Kliegman JI, Jiang L, Kuo D, Tosti E, Kim HS, Edelmann W, Keogh MC, Greene D, Tang C, Cunningham P, Shokat KM, Cagney G, Svensson JP, Guthrie C, Espenshade PJ, Ideker T, Krogan NJ.

Mol Cell. 2012 Jun 8;46(5):691-704. doi: 10.1016/j.molcel.2012.05.028.


Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal.

Hunkapiller J, Shen Y, Diaz A, Cagney G, McCleary D, Ramalho-Santos M, Krogan N, Ren B, Song JS, Reiter JF.

PLoS Genet. 2012;8(3):e1002576. doi: 10.1371/journal.pgen.1002576. Epub 2012 Mar 15.


Global landscape of HIV-human protein complexes.

Jäger S, Cimermancic P, Gulbahce N, Johnson JR, McGovern KE, Clarke SC, Shales M, Mercenne G, Pache L, Li K, Hernandez H, Jang GM, Roth SL, Akiva E, Marlett J, Stephens M, D'Orso I, Fernandes J, Fahey M, Mahon C, O'Donoghue AJ, Todorovic A, Morris JH, Maltby DA, Alber T, Cagney G, Bushman FD, Young JA, Chanda SK, Sundquist WI, Kortemme T, Hernandez RD, Craik CS, Burlingame A, Sali A, Frankel AD, Krogan NJ.

Nature. 2011 Dec 21;481(7381):365-70. doi: 10.1038/nature10719.


Imputing and predicting quantitative genetic interactions in epistatic MAPs.

Ryan C, Cagney G, Krogan N, Cunningham P, Greene D.

Methods Mol Biol. 2011;781:353-61. doi: 10.1007/978-1-61779-276-2_17.


Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs.

Casey F, Krogan N, Shields DC, Cagney G.

BMC Syst Biol. 2011 Aug 22;5:133. doi: 10.1186/1752-0509-5-133.


Identification of β2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods.

Johnston O, Cassidy H, O'Connell S, O'Riordan A, Gallagher W, Maguire PB, Wynne K, Cagney G, Ryan MP, Conlon PJ, McMorrow T.

Proteomics Clin Appl. 2011 Aug;5(7-8):422-31. doi: 10.1002/prca.201000160. Epub 2011 Jul 13.


Improved functional overview of protein complexes using inferred epistatic relationships.

Ryan C, Greene D, Guénolé A, van Attikum H, Krogan NJ, Cunningham P, Cagney G.

BMC Syst Biol. 2011 May 23;5:80. doi: 10.1186/1752-0509-5-80.


Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia.

Agbor TA, Cheong A, Comerford KM, Scholz CC, Bruning U, Clarke A, Cummins EP, Cagney G, Taylor CT.

J Biol Chem. 2011 Feb 11;286(6):4718-26. doi: 10.1074/jbc.M110.115931. Epub 2010 Dec 1.


Epistatic relationships reveal the functional organization of yeast transcription factors.

Zheng J, Benschop JJ, Shales M, Kemmeren P, Greenblatt J, Cagney G, Holstege F, Li H, Krogan NJ.

Mol Syst Biol. 2010 Oct 5;6:420. doi: 10.1038/msb.2010.77.


Quantitative genetic interactions reveal biological modularity.

Beltrao P, Cagney G, Krogan NJ.

Cell. 2010 May 28;141(5):739-45. doi: 10.1016/j.cell.2010.05.019.

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