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Items: 1 to 20 of 80


The evolutionary history of genes involved in spoken and written language: beyond FOXP2.

Mozzi A, Forni D, Clerici M, Pozzoli U, Mascheretti S, Guerini FR, Riva S, Bresolin N, Cagliani R, Sironi M.

Sci Rep. 2016 Feb 25;6:22157. doi: 10.1038/srep22157.


The mammalian complement system as an epitome of host-pathogen genetic conflicts.

Cagliani R, Forni D, Filippi G, Mozzi A, De Gioia L, Pontremoli C, Pozzoli U, Bresolin N, Clerici M, Sironi M.

Mol Ecol. 2016 Mar;25(6):1324-39. doi: 10.1111/mec.13558.


Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses.

Forni D, Cagliani R, Mozzi A, Pozzoli U, Al-Daghri N, Clerici M, Sironi M.

J Virol. 2016 Jan 20;90(7):3627-39. doi: 10.1128/JVI.02988-15.


The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses.

Forni D, Filippi G, Cagliani R, De Gioia L, Pozzoli U, Al-Daghri N, Clerici M, Sironi M.

Sci Rep. 2015 Sep 25;5:14480. doi: 10.1038/srep14480.


Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection.

Sironi M, Biasin M, Pontremoli C, Cagliani R, Saulle I, Trabattoni D, Vichi F, Lo Caputo S, Mazzotta F, Aguilar-Jimenez W, Rugeles MT, Cedeno S, Sanchez J, Brander C, Clerici M.

Retrovirology. 2015 Sep 24;12:80. doi: 10.1186/s12977-015-0206-0.


Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.

Pontremoli C, Mozzi A, Forni D, Cagliani R, Pozzoli U, Menozzi G, Vertemara J, Bresolin N, Clerici M, Sironi M.

Genome Biol Evol. 2015 Aug 28;7(9):2569-84. doi: 10.1093/gbe/evv166.


Positive selection underlies the species-specific binding of Plasmodium falciparum RH5 to human basigin.

Forni D, Pontremoli C, Cagliani R, Pozzoli U, Clerici M, Sironi M.

Mol Ecol. 2015 Sep;24(18):4711-22. doi: 10.1111/mec.13354. Epub 2015 Sep 7.


Diverse selective regimes shape genetic diversity at ADAR genes and at their coding targets.

Forni D, Mozzi A, Pontremoli C, Vertemara J, Pozzoli U, Biasin M, Bresolin N, Clerici M, Cagliani R, Sironi M.

RNA Biol. 2015;12(2):149-61. doi: 10.1080/15476286.2015.1017215.


Evolutionary insights into host-pathogen interactions from mammalian sequence data.

Sironi M, Cagliani R, Forni D, Clerici M.

Nat Rev Genet. 2015 Apr;16(4):224-36. doi: 10.1038/nrg3905. Review.


OASes and STING: adaptive evolution in concert.

Mozzi A, Pontremoli C, Forni D, Clerici M, Pozzoli U, Bresolin N, Cagliani R, Sironi M.

Genome Biol Evol. 2015 Mar 9;7(4):1016-32. doi: 10.1093/gbe/evv046.


Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders.

Forni D, Pozzoli U, Cagliani R, Tresoldi C, Menozzi G, Riva S, Guerini FR, Comi GP, Bolognesi E, Bresolin N, Clerici M, Sironi M.

Genome Biol. 2014;15(10):499.


Albuminoid genes: evolving at the interface of dispensability and selection.

Mozzi A, Forni D, Cagliani R, Pozzoli U, Vertemara J, Bresolin N, Sironi M.

Genome Biol Evol. 2014 Oct 27;6(11):2983-97. doi: 10.1093/gbe/evu235.


A regulatory polymorphism in HAVCR2 modulates susceptibility to HIV-1 infection.

Sironi M, Biasin M, Gnudi F, Cagliani R, Saulle I, Forni D, Rainone V, Trabattoni D, Garziano M, Mazzotta F, Real LM, Rivero-Juarez A, Caruz A, Lo Caputo S, Clerici M.

PLoS One. 2014 Sep 2;9(9):e106442. doi: 10.1371/journal.pone.0106442. eCollection 2014.


The CCR5Δ32 allele is not a major predisposing factor for severe H1N1pdm09 infection.

Sironi M, Cagliani R, Pontremoli C, Rossi M, Migliorino G, Clerici M, Gori A.

BMC Res Notes. 2014 Aug 7;7:504. doi: 10.1186/1756-0500-7-504.


Evolutionary analysis identifies an MX2 haplotype associated with natural resistance to HIV-1 infection.

Sironi M, Biasin M, Cagliani R, Gnudi F, Saulle I, Ibba S, Filippi G, Yahyaei S, Tresoldi C, Riva S, Trabattoni D, De Gioia L, Lo Caputo S, Mazzotta F, Forni D, Pontremoli C, Pineda JA, Pozzoli U, Rivero-Juarez A, Caruz A, Clerici M.

Mol Biol Evol. 2014 Sep;31(9):2402-14. doi: 10.1093/molbev/msu193. Epub 2014 Jun 14.


No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis.

Guerini FR, Clerici M, Cagliani R, Malhotra S, Montalban X, Forni D, Agliardi C, Riva S, Caputo D, Galimberti D, Asselta R, Fenoglio C, Scarpini E, Comi GP, Bresolin N, Comabella M, Sironi M.

J Neuroimmunol. 2014 Jun 15;271(1-2):49-52. doi: 10.1016/j.jneuroim.2014.04.006. Epub 2014 Apr 16.


Ancient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors.

Cagliani R, Forni D, Biasin M, Comabella M, Guerini FR, Riva S, Pozzoli U, Agliardi C, Caputo D, Malhotra S, Montalban X, Bresolin N, Clerici M, Sironi M.

Genome Biol Evol. 2014 Apr;6(4):830-45. doi: 10.1093/gbe/evu066.


An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.

Forni D, Cagliani R, Tresoldi C, Pozzoli U, De Gioia L, Filippi G, Riva S, Menozzi G, Colleoni M, Biasin M, Lo Caputo S, Mazzotta F, Comi GP, Bresolin N, Clerici M, Sironi M.

PLoS Genet. 2014 Mar 27;10(3):e1004189. doi: 10.1371/journal.pgen.1004189. eCollection 2014 Mar.


ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior.

Forni D, Cleynen I, Ferrante M, Cassinotti A, Cagliani R, Ardizzone S, Vermeire S, Fichera M, Lombardini M, Maconi G, de Franchis R, Asselta R, Biasin M, Clerici M, Sironi M.

J Crohns Colitis. 2014 Jun;8(6):489-94. doi: 10.1016/j.crohns.2013.10.014. Epub 2013 Nov 21.


RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I.

Cagliani R, Forni D, Tresoldi C, Pozzoli U, Filippi G, Rainone V, De Gioia L, Clerici M, Sironi M.

J Mol Biol. 2014 Mar 20;426(6):1351-65. doi: 10.1016/j.jmb.2013.10.040. Epub 2013 Nov 7.

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