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The early history and emergence of molecular functions and modular scale-free network behavior.

Aziz MF, Caetano-Anollés K, Caetano-Anollés G.

Sci Rep. 2016 Apr 28;6:25058. doi: 10.1038/srep25058.


Creationism and intelligent design are incompatible with scientific progress: A response to Shanta and Vêdanta.

Caetano-Anollés G.

Commun Integr Biol. 2016 Jan 8;9(1):e1123356. doi: 10.1080/19420889.2015.1123356. eCollection 2016 Jan-Feb.


A phylogenomic data-driven exploration of viral origins and evolution.

Nasir A, Caetano-Anollés G.

Sci Adv. 2015 Sep 25;1(8):e1500527. doi: 10.1126/sciadv.1500527. eCollection 2015 Sep.


The organization of domains in proteins obeys Menzerath-Altmann's law of language.

Shahzad K, Mittenthal JE, Caetano-Anollés G.

BMC Syst Biol. 2015 Aug 11;9:44. doi: 10.1186/s12918-015-0192-9.


Lokiarchaeota: eukaryote-like missing links from microbial dark matter?

Nasir A, Kim KM, Caetano-Anollés G.

Trends Microbiol. 2015 Aug;23(8):448-50. doi: 10.1016/j.tim.2015.06.001. Epub 2015 Jun 22.


Ribosomal accretion, apriorism and the phylogenetic method: a response to Petrov and Williams.

Caetano-Anollés D, Caetano-Anollés G.

Front Genet. 2015 Jun 2;6:194. doi: 10.3389/fgene.2015.00194. eCollection 2015.


Ancestral Insertions and Expansions of rRNA do not Support an Origin of the Ribosome in Its Peptidyl Transferase Center.

Caetano-Anollés G.

J Mol Evol. 2015 Apr;80(3-4):162-5. doi: 10.1007/s00239-015-9677-9. Epub 2015 Apr 12.


Untangling the origin of viruses and their impact on cellular evolution.

Nasir A, Sun FJ, Kim KM, Caetano-Anollés G.

Ann N Y Acad Sci. 2015 Apr;1341:61-74. doi: 10.1111/nyas.12735. Epub 2015 Mar 10. Review.


The absence of protein Y4yS affects negatively the abundance of T3SS Mesorhizobium loti secretin, RhcC2, in bacterial membranes.

Mercante V, Duarte CM, Sánchez CM, Zalguizuri A, Caetano-Anollés G, Lepek VC.

Front Plant Sci. 2015 Jan 30;6:12. doi: 10.3389/fpls.2015.00012. eCollection 2015.


Computing the origin and evolution of the ribosome from its structure - Uncovering processes of macromolecular accretion benefiting synthetic biology.

Caetano-Anollés G, Caetano-Anollés D.

Comput Struct Biotechnol J. 2015 Jul 26;13:427-47. doi: 10.1016/j.csbj.2015.07.003. eCollection 2015. Review.


A calibrated chronology of biochemistry reveals a stem line of descent responsible for planetary biodiversity.

Caetano-Anollés G, Mittenthal JE, Caetano-Anollés D, Kim KM.

Front Genet. 2014 Sep 11;5:306. doi: 10.3389/fgene.2014.00306. eCollection 2014.


A phylogenomic census of molecular functions identifies modern thermophilic archaea as the most ancient form of cellular life.

Nasir A, Kim KM, Caetano-Anollés G.

Archaea. 2014 Aug 31;2014:706468. doi: 10.1155/2014/706468. eCollection 2014.


A tree of cellular life inferred from a genomic census of molecular functions.

Kim KM, Nasir A, Hwang K, Caetano-Anollés G.

J Mol Evol. 2014 Dec;79(5-6):240-62. doi: 10.1007/s00239-014-9637-9. Epub 2014 Aug 17.


The origin and evolution of the archaeal domain.

Caetano-Anollés G, Kim KM.

Archaea. 2014 Jun 4;2014:915828. doi: 10.1155/2014/915828. eCollection 2014. No abstract available.


Archaea: the first domain of diversified life.

Caetano-Anollés G, Nasir A, Zhou K, Caetano-Anollés D, Mittenthal JE, Sun FJ, Kim KM.

Archaea. 2014 Jun 2;2014:590214. doi: 10.1155/2014/590214. eCollection 2014. Review.


The natural history of biocatalytic mechanisms.

Nath N, Mitchell JB, Caetano-Anollés G.

PLoS Comput Biol. 2014 May 29;10(5):e1003642. doi: 10.1371/journal.pcbi.1003642. eCollection 2014 May.


The natural history of transfer RNA and its interactions with the ribosome.

Caetano-Anollés G, Sun FJ.

Front Genet. 2014 May 9;5:127. doi: 10.3389/fgene.2014.00127. eCollection 2014. No abstract available.


The distribution and impact of viral lineages in domains of life.

Nasir A, Forterre P, Kim KM, Caetano-Anollés G.

Front Microbiol. 2014 Apr 30;5:194. doi: 10.3389/fmicb.2014.00194. eCollection 2014. No abstract available.


Global patterns of protein domain gain and loss in superkingdoms.

Nasir A, Kim KM, Caetano-Anollés G.

PLoS Comput Biol. 2014 Jan 30;10(1):e1003452. doi: 10.1371/journal.pcbi.1003452. eCollection 2014 Jan.


Comparative analysis of proteomes and functionomes provides insights into origins of cellular diversification.

Nasir A, Caetano-Anollés G.

Archaea. 2013 Dec 31;2013:648746. doi: 10.1155/2013/648746. eCollection 2013.

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