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Pharmacodynamic Characteristics of Nephrotoxicity Associated With Vancomycin Use in Children.

Le J, Ny P, Capparelli E, Lane J, Ngu B, Muus R, Romanowski G, Vo T, Bradley J.

J Pediatric Infect Dis Soc. 2015 Dec;4(4):e109-16. doi: 10.1093/jpids/piu110. Epub 2014 Nov 3.


Cell-Associated HIV-1 DNA and RNA Decay Dynamics During Early Combination Antiretroviral Therapy in HIV-1-Infected Infants.

Uprety P, Chadwick EG, Rainwater-Lovett K, Ziemniak C, Luzuriaga K, Capparelli EV, Yenokyan G, Persaud D.

Clin Infect Dis. 2015 Dec 15;61(12):1862-70. doi: 10.1093/cid/civ688. Epub 2015 Aug 13.


Maraviroc Pharmacokinetics in HIV-1-Infected Pregnant Women.

Colbers A, Best B, Schalkwijk S, Wang J, Stek A, Hidalgo Tenorio C, Hawkins D, Taylor G, Kreitchmann R, Burchett S, Haberl A, Kabeya K, van Kasteren M, Smith E, Capparelli E, Burger D, Mirochnick M; PANNA Network and the IMPAACT 1026 Study Team.

Clin Infect Dis. 2015 Nov 15;61(10):1582-9. doi: 10.1093/cid/civ587. Epub 2015 Jul 22.


Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study.

Le J, Capparelli EV, Wahid U, Wu YS, Romanowski GL, Tran TM, Nguyen A, Bradley JS.

Clin Ther. 2015 Jun 1;37(6):1340-51. doi: 10.1016/j.clinthera.2015.05.006. Epub 2015 May 29.


Pharmacokinetics of Once Versus Twice Daily Darunavir in Pregnant HIV-Infected Women.

Stek A, Best BM, Wang J, Capparelli EV, Burchett SK, Kreitchmann R, Rungruengthanakit K, Cressey TR, Mofenson LM, Smith E, Shapiro D, Mirochnick M.

J Acquir Immune Defic Syndr. 2015 Sep 1;70(1):33-41. doi: 10.1097/QAI.0000000000000668.


Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation.

Watt KM, Gonzalez D, Benjamin DK Jr, Brouwer KL, Wade KC, Capparelli E, Barrett J, Cohen-Wolkowiez M.

Antimicrob Agents Chemother. 2015 Jul;59(7):3935-43. doi: 10.1128/AAC.00102-15. Epub 2015 Apr 20.


Optimizing pediatric esmolol dosing using computerized practitioner order entry.

Chao T, Perry JC, Romanowski GL, Tremoulet AH, Capparelli EV.

J Pediatr Pharmacol Ther. 2014 Oct-Dec;19(4):302-9. doi: 10.5863/1551-6776-19.4.302.


The effect of malnutrition on the pharmacokinetics and virologic outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, Uganda.

Bartelink IH, Savic RM, Dorsey G, Ruel T, Gingrich D, Scherpbier HJ, Capparelli E, Jullien V, Young SL, Achan J, Plenty A, Charlebois E, Kamya M, Havlir D, Aweeka F.

Pediatr Infect Dis J. 2015 Mar;34(3):e63-70. doi: 10.1097/INF.0000000000000603.


Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing.

Nikanjam M, Stewart CF, Takimoto CH, Synold TW, Beaty O, Fouladi M, Capparelli EV.

Cancer Chemother Pharmacol. 2015 Mar;75(3):495-503. doi: 10.1007/s00280-014-2667-6. Epub 2015 Jan 4.


Population-Based Pharmacokinetic Modeling of Vancomycin in Children with Renal Insufficiency.

Le J, Vaida F, Nguyen E, Adler-Shohet FC, Romanowski G, Kim J, Vo T, Capparelli EV.

J Pharmacol Clin Toxicol. 2014;2(1):1017-1026.


Lopinavir/ritonavir plus lamivudine and abacavir or zidovudine dose ratios for paediatric fixed-dose combinations.

Bouazza N, Foissac F, Fauchet F, Burger D, Kiechel JR, Treluyer JM, Capparelli EV, Lallemant M, Urien S.

Antivir Ther. 2015;20(2):225-33. doi: 10.3851/IMP2876. Epub 2014 Oct 3.


Variable and suboptimal nevirapine levels in infants given single-dose nevirapine at birth without maternal prophylaxis.

Dross SE, Rossi SS, Beck IA, Micek MA, Blanco AJ, Seidel KD, Montoya P, Capparelli EV, Frenkel LM.

AIDS. 2014 Oct 23;28(16):2491-3. doi: 10.1097/QAD.0000000000000451. No abstract available.


Impact of body weight and missed doses on lopinavir concentrations with standard and increased lopinavir/ritonavir doses during late pregnancy.

Cressey TR, Urien S, Capparelli EV, Best BM, Buranabanjasatean S, Limtrakul A, Rawangban B, Sabsanong P, Treluyer JM, Jourdain G, Stek A, Lallemant M, Mirochnick M.

J Antimicrob Chemother. 2015 Jan;70(1):217-24. doi: 10.1093/jac/dku367. Epub 2014 Sep 25.


Predictive performance of a gentamicin population pharmacokinetic model in neonates receiving full-body hypothermia.

Sampson MR, Frymoyer A, Rattray B, Cotten CM, Smith PB, Capparelli E, Bonifacio SL, Cohen-Wolkowiez M.

Ther Drug Monit. 2014 Oct;36(5):584-9. doi: 10.1097/FTD.0000000000000056.


Raltegravir pharmacokinetics during pregnancy.

Watts DH, Stek A, Best BM, Wang J, Capparelli EV, Cressey TR, Aweeka F, Lizak P, Kreitchmann R, Burchett SK, Shapiro DE, Hawkins E, Smith E, Mirochnick M; IMPAACT 1026s study team.

J Acquir Immune Defic Syndr. 2014 Dec 1;67(4):375-81. doi: 10.1097/QAI.0000000000000318.


Auranofin is highly efficacious against Toxoplasma gondii in vitro and in an in vivo experimental model of acute toxoplasmosis.

Andrade RM, Chaparro JD, Capparelli E, Reed SL.

PLoS Negl Trop Dis. 2014 Jul 31;8(7):e2973. doi: 10.1371/journal.pntd.0002973. eCollection 2014.


Pharmacokinetics and pharmacodynamics of antifungals in children: clinical implications.

Autmizguine J, Guptill JT, Cohen-Wolkowiez M, Benjamin DK Jr, Capparelli EV.

Drugs. 2014 Jun;74(8):891-909. doi: 10.1007/s40265-014-0227-3. Review.


Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections.

Autmizguine J, Moran C, Gonzalez D, Capparelli EV, Smith PB, Grant GA, Benjamin DK Jr, Cohen-Wolkowiez M, Watt KM.

Pediatr Infect Dis J. 2014 Oct;33(10):e270-2. doi: 10.1097/INF.0000000000000385.


Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design.

Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK Jr, Capparelli EV, Cohen-Wolkowiez M; Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network.

Antimicrob Agents Chemother. 2014 Jun;58(6):3013-20. doi: 10.1128/AAC.02374-13. Epub 2014 Mar 10.


Developmental pharmacokinetics of piperacillin and tazobactam using plasma and dried blood spots from infants.

Cohen-Wolkowiez M, Watt KM, Zhou C, Bloom BT, Poindexter B, Castro L, Gao J, Capparelli EV, Benjamin DK Jr, Smith PB.

Antimicrob Agents Chemother. 2014 May;58(5):2856-65. doi: 10.1128/AAC.02139-13. Epub 2014 Mar 10.

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