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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1841 1
1845 1
1851 1
1853 1
1854 1
1865 1
1869 1
1882 1
1883 1
1885 1
1887 1
1888 2
1889 1
1892 1
1897 1
1902 1
1907 1
1918 1
1920 1
1924 1
1929 1
1938 1
1940 1
1944 1
1946 3
1947 6
1948 3
1949 3
1950 7
1951 13
1952 12
1953 11
1954 6
1955 6
1956 10
1957 14
1958 13
1959 8
1960 9
1961 9
1962 5
1963 16
1964 19
1965 24
1966 33
1967 22
1968 30
1969 35
1970 40
1971 44
1972 52
1973 59
1974 60
1975 149
1976 168
1977 187
1978 231
1979 211
1980 249
1981 266
1982 302
1983 338
1984 398
1985 425
1986 417
1987 412
1988 478
1989 542
1990 603
1991 569
1992 589
1993 610
1994 669
1995 699
1996 767
1997 789
1998 880
1999 938
2000 1028
2001 1001
2002 1103
2003 1116
2004 1239
2005 1398
2006 1389
2007 1406
2008 1615
2009 1670
2010 1829
2011 1948
2012 2126
2013 2475
2014 2485
2015 2581
2016 2673
2017 2783
2018 2809
2019 3126
2020 3621
2021 3856
2022 3726
2023 3711
2024 1264

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60,185 results

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Page 1
Cap 1 Messenger RNA Synthesis with Co-transcriptional CleanCap() Analog by In Vitro Transcription.
Henderson JM, Ujita A, Hill E, Yousif-Rosales S, Smith C, Ko N, McReynolds T, Cabral CR, Escamilla-Powers JR, Houston ME. Henderson JM, et al. Curr Protoc. 2021 Feb;1(2):e39. doi: 10.1002/cpz1.39. Curr Protoc. 2021. PMID: 33524237
Synthetic messenger RNA (mRNA)-based therapeutics are an increasingly popular approach to gene and cell therapies, genome engineering, enzyme replacement therapy, and now, during the global SARS-CoV-2 pandemic, vaccine development. mRNA for such purposes can be synthesized throug …
Synthetic messenger RNA (mRNA)-based therapeutics are an increasingly popular approach to gene and cell therapies, genome engineering, enzym …
The multifaceted eukaryotic cap structure.
Pelletier J, Schmeing TM, Sonenberg N. Pelletier J, et al. Wiley Interdiscip Rev RNA. 2021 Mar;12(2):e1636. doi: 10.1002/wrna.1636. Epub 2020 Dec 9. Wiley Interdiscip Rev RNA. 2021. PMID: 33300197 Review.
It is also required for stimulating translation initiation of many cytoplasmic mRNAs and serves to protect mRNAs from degradation. These functional properties of the cap are mediated by several cap binding proteins (CBPs) involved in nuclear and cytoplasmic gene exp …
It is also required for stimulating translation initiation of many cytoplasmic mRNAs and serves to protect mRNAs from degradation. These fun …
Mechanisms of fibrous cap formation in atherosclerosis.
Alonso-Herranz L, Albarrán-Juárez J, Bentzon JF. Alonso-Herranz L, et al. Front Cardiovasc Med. 2023 Aug 21;10:1254114. doi: 10.3389/fcvm.2023.1254114. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37671141 Free PMC article. Review.
The fibrous cap is formed by smooth muscle cells that accumulate beneath the plaque endothelium. Cap rupture is the main cause of coronary thrombosis, leading to infarction and sudden cardiac death. ...
The fibrous cap is formed by smooth muscle cells that accumulate beneath the plaque endothelium. Cap rupture is the main cause …
Cap-binding complex (CBC).
Gonatopoulos-Pournatzis T, Cowling VH. Gonatopoulos-Pournatzis T, et al. Biochem J. 2014 Jan 15;457(2):231-42. doi: 10.1042/BJ20131214. Biochem J. 2014. PMID: 24354960 Free PMC article. Review.
The 7mG (7-methylguanosine cap) formed on mRNA is fundamental to eukaryotic gene expression. Protein complexes recruited to 7mG mediate key processing events throughout the lifetime of the transcript. One of the most important mediators of 7mG functions is CBC (cap- …
The 7mG (7-methylguanosine cap) formed on mRNA is fundamental to eukaryotic gene expression. Protein complexes recruited to 7mG media …
The Nuclear Cap-Binding Complex, a multitasking binding partner of RNA polymerase II transcripts.
Kataoka N. Kataoka N. J Biochem. 2023 Dec 20;175(1):9-15. doi: 10.1093/jb/mvad081. J Biochem. 2023. PMID: 37830942 Free PMC article. Review.
In eukaryotic cells, RNAs transcribed by RNA polymerase-II receive the modification at the 5' end. This structure is called the cap structure. The cap structure has a fundamental role for translation initiation by recruiting eukaryotic translation initiation factor …
In eukaryotic cells, RNAs transcribed by RNA polymerase-II receive the modification at the 5' end. This structure is called the cap s …
Recent Advances in Modified Cap Analogs: Synthesis, Biochemical Properties, and mRNA Based Vaccines.
Shanmugasundaram M, Senthilvelan A, Kore AR. Shanmugasundaram M, et al. Chem Rec. 2022 Aug;22(8):e202200005. doi: 10.1002/tcr.202200005. Epub 2022 Apr 14. Chem Rec. 2022. PMID: 35420257 Free PMC article. Review.
Notably, trinucleotide cap analogs outweigh dinucleotide cap analogs in terms of capping efficiency and translational properties. This review focuses on the recent development in the synthesis of various dinucleotide cap analogs such as dinucleotide containin …
Notably, trinucleotide cap analogs outweigh dinucleotide cap analogs in terms of capping efficiency and translational properti …
Shedding the Last Layer: Mechanisms of Root Cap Cell Release.
Kumar N, Iyer-Pascuzzi AS. Kumar N, et al. Plants (Basel). 2020 Mar 1;9(3):308. doi: 10.3390/plants9030308. Plants (Basel). 2020. PMID: 32121604 Free PMC article. Review.
To perform its functions, the position and size of the root cap remains stable throughout root growth. This occurs due to constant root cap cell turnover, in which the last layer of the root cap is released, and new root cap cells are produced. ...Rece …
To perform its functions, the position and size of the root cap remains stable throughout root growth. This occurs due to constant ro …
Burden of Community-Acquired Pneumonia and Unmet Clinical Needs.
Ferreira-Coimbra J, Sarda C, Rello J. Ferreira-Coimbra J, et al. Adv Ther. 2020 Apr;37(4):1302-1318. doi: 10.1007/s12325-020-01248-7. Epub 2020 Feb 18. Adv Ther. 2020. PMID: 32072494 Free PMC article. Review.
CAP microbiology has been altered by new molecular diagnostic tests that have turned viruses into the most identified pathogens, notwithstanding uncertainties about the specific role of each virus in CAP pathogenesis. ...Pathogens from specific regions should also b …
CAP microbiology has been altered by new molecular diagnostic tests that have turned viruses into the most identified pathogens, notw …
Cap and cap-binding proteins in the control of gene expression.
Topisirovic I, Svitkin YV, Sonenberg N, Shatkin AJ. Topisirovic I, et al. Wiley Interdiscip Rev RNA. 2011 Mar-Apr;2(2):277-98. doi: 10.1002/wrna.52. Epub 2010 Oct 28. Wiley Interdiscip Rev RNA. 2011. PMID: 21957010 Review.
Cap-binding proteins specifically bind to the cap structure and mediate its functions in the cell. ...In this review, we highlight recent findings on the role of the cap structure and cap-binding proteins in the regulation of gene expression. ...
Cap-binding proteins specifically bind to the cap structure and mediate its functions in the cell. ...In this review, we highl …
The root cap: a short story of life and death.
Kumpf RP, Nowack MK. Kumpf RP, et al. J Exp Bot. 2015 Sep;66(19):5651-62. doi: 10.1093/jxb/erv295. Epub 2015 Jun 11. J Exp Bot. 2015. PMID: 26068468 Review.
Modern plant biology has unravelled that many of the functions that Darwin attributed to the root tip are actually accomplished by a particular organ-the root cap. The root cap surrounds and protects the meristematic stem cells at the growing root tip. Due to this v …
Modern plant biology has unravelled that many of the functions that Darwin attributed to the root tip are actually accomplished by a particu …
60,185 results
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