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Results: 1 to 20 of 179

1.

Achieving high-sensitivity for clinical applications using augmented exome sequencing.

Patwardhan A, Harris J, Leng N, Bartha G, Church DM, Luo S, Haudenschild C, Pratt M, Zook J, Salit M, Tirch J, Morra M, Chervitz S, Li M, Clark M, Garcia S, Chandratillake G, Kirk S, Ashley E, Snyder M, Altman R, Bustamante C, Butte AJ, West J, Chen R.

Genome Med. 2015 Jul 16;7(1):71. doi: 10.1186/s13073-015-0197-4. eCollection 2015.

2.

Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research.

Chen B, Sirota M, Fan-Minogue H, Hadley D, Butte AJ.

BMC Med Genomics. 2015;8 Suppl 2:S5. doi: 10.1186/1755-8794-8-S2-S5. Epub 2015 May 29.

3.

The receptor CD44 is associated with systemic insulin resistance and proinflammatory macrophages in human adipose tissue.

Liu LF, Kodama K, Wei K, Tolentino LL, Choi O, Engleman EG, Butte AJ, McLaughlin T.

Diabetologia. 2015 Jul;58(7):1579-86. doi: 10.1007/s00125-015-3603-y. Epub 2015 May 9.

PMID:
25952479
4.

A survey of current trends in computational drug repositioning.

Li J, Zheng S, Chen B, Butte AJ, Swamidass SJ, Lu Z.

Brief Bioinform. 2015 Mar 31. pii: bbv020. [Epub ahead of print]

PMID:
25832646
5.

Robust meta-analysis of gene expression using the elastic net.

Hughey JJ, Butte AJ.

Nucleic Acids Res. 2015 Jul 13;43(12):e79. doi: 10.1093/nar/gkv229. Epub 2015 Mar 31.

6.

Repurpose terbutaline sulfate for amyotrophic lateral sclerosis using electronic medical records.

Paik H, Chung AY, Park HC, Park RW, Suk K, Kim J, Kim H, Lee K, Butte AJ.

Sci Rep. 2015 Mar 5;5:8580. doi: 10.1038/srep08580.

7.

Heterogeneity in recent-onset type 1 diabetes - a clinical trial perspective.

Bollyky JB, Xu P, Butte AJ, Wilson DM, Beam CA, Greenbaum CJ; Type 1 Diabetes TrialNet Study Group.

Diabetes Metab Res Rev. 2015 Feb 17. doi: 10.1002/dmrr.2643. [Epub ahead of print]

PMID:
25689602
8.

Variation in the human immune system is largely driven by non-heritable influences.

Brodin P, Jojic V, Gao T, Bhattacharya S, Angel CJ, Furman D, Shen-Orr S, Dekker CL, Swan GE, Butte AJ, Maecker HT, Davis MM.

Cell. 2015 Jan 15;160(1-2):37-47. doi: 10.1016/j.cell.2014.12.020.

PMID:
25594173
9.

A systematic assessment of linking gene expression with genetic variants for prioritizing candidate targets.

Fan-Minogue H, Chen B, Sikora-Wohlfeld W, Sirota M, Butte AJ.

Pac Symp Biocomput. 2015:383-94.

10.
11.

Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells.

Duscher D, Rennert RC, Januszyk M, Anghel E, Maan ZN, Whittam AJ, Perez MG, Kosaraju R, Hu MS, Walmsley GG, Atashroo D, Khong S, Butte AJ, Gurtner GC.

Sci Rep. 2014 Nov 21;4:7144. doi: 10.1038/srep07144.

12.

Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice.

Kodama K, Toda K, Morinaga S, Yamada S, Butte AJ.

Diabetes. 2015 Mar;64(3):867-75. doi: 10.2337/db14-0149. Epub 2014 Oct 7.

13.

Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo.

Ehmer U, Zmoos AF, Auerbach RK, Vaka D, Butte AJ, Kay MA, Sage J.

Cell Rep. 2014 Jul 24;8(2):371-81. doi: 10.1016/j.celrep.2014.06.025. Epub 2014 Jul 10.

14.

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.

Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O.

Nature. 2014 Jun 12;510(7504):283-7. doi: 10.1038/nature13320. Epub 2014 May 21.

15.

ImmPort: disseminating data to the public for the future of immunology.

Bhattacharya S, Andorf S, Gomes L, Dunn P, Schaefer H, Pontius J, Berger P, Desborough V, Smith T, Campbell J, Thomson E, Monteiro R, Guimaraes P, Walters B, Wiser J, Butte AJ.

Immunol Res. 2014 May;58(2-3):234-9. doi: 10.1007/s12026-014-8516-1.

PMID:
24791905
16.

Disease risk factors identified through shared genetic architecture and electronic medical records.

Li L, Ruau DJ, Patel CJ, Weber SC, Chen R, Tatonetti NP, Dudley JT, Butte AJ.

Sci Transl Med. 2014 Apr 30;6(234):234ra57. doi: 10.1126/scitranslmed.3007191.

17.

Diabetes irreversibly depletes bone marrow-derived mesenchymal progenitor cell subpopulations.

Januszyk M, Sorkin M, Glotzbach JP, Vial IN, Maan ZN, Rennert RC, Duscher D, Thangarajah H, Longaker MT, Butte AJ, Gurtner GC.

Diabetes. 2014 Sep;63(9):3047-56. doi: 10.2337/db13-1366. Epub 2014 Apr 16.

18.

Collaborative biomedicine in the age of big data: the case of cancer.

Shaikh AR, Butte AJ, Schully SD, Dalton WS, Khoury MJ, Hesse BW.

J Med Internet Res. 2014 Apr 7;16(4):e101. doi: 10.2196/jmir.2496.

19.

Whole-exome sequencing reveals TopBP1 as a novel gene in idiopathic pulmonary arterial hypertension.

de Jesus Perez VA, Yuan K, Lyuksyutova MA, Dewey F, Orcholski ME, Shuffle EM, Mathur M, Yancy L Jr, Rojas V, Li CG, Cao A, Alastalo TP, Khazeni N, Cimprich KA, Butte AJ, Ashley E, Zamanian RT.

Am J Respir Crit Care Med. 2014 May 15;189(10):1260-72. doi: 10.1164/rccm.201310-1749OC.

20.

A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma.

Chen R, Khatri P, Mazur PK, Polin M, Zheng Y, Vaka D, Hoang CD, Shrager J, Xu Y, Vicent S, Butte AJ, Sweet-Cordero EA.

Cancer Res. 2014 May 15;74(10):2892-902. doi: 10.1158/0008-5472.CAN-13-2775. Epub 2014 Mar 20.

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