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Targeting polo-like kinase 1, a regulator of p53, in the treatment of adrenocortical carcinoma.

Bussey KJ, Bapat A, Linnehan C, Wandoloski M, Dastrup E, Rogers E, Gonzales P, Demeure MJ.

Clin Transl Med. 2016 Dec;5(1):1. doi: 10.1186/s40169-015-0080-3. Epub 2016 Jan 11.


Whole-genome sequencing of an aggressive BRAF wild-type papillary thyroid cancer identified EML4-ALK translocation as a therapeutic target.

Demeure MJ, Aziz M, Rosenberg R, Gurley SD, Bussey KJ, Carpten JD.

World J Surg. 2014 Jun;38(6):1296-305. doi: 10.1007/s00268-014-2485-3.


PTTG1 overexpression in adrenocortical cancer is associated with poor survival and represents a potential therapeutic target.

Demeure MJ, Coan KE, Grant CS, Komorowski RA, Stephan E, Sinari S, Mount D, Bussey KJ.

Surgery. 2013 Dec;154(6):1405-16; discussion 1416. doi: 10.1016/j.surg.2013.06.058.


Detection of an atypical teratoid rhabdoid brain tumor gene deletion in circulating blood using next-generation sequencing.

Chakravadhanula M, Tembe W, Legendre C, Carpentieri D, Liang WS, Bussey KJ, Carpten J, Berens ME, Bhardwaj RD.

J Child Neurol. 2014 Sep;29(9):NP81-5. doi: 10.1177/0883073813503904. Epub 2013 Oct 17.


A fly in the ointment: reassessing mitotane's role in the treatment of adrenocortical carcinoma.

Bapat AA, Demeure MJ, Bussey KJ.

Pharmacogenomics. 2012 Aug;13(11):1207-9. doi: 10.2217/pgs.12.90. No abstract available.


Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling.

Creamer MS, Stites EC, Aziz M, Cahill JA, Tan CW, Berens ME, Han H, Bussey KJ, Von Hoff DD, Hlavacek WS, Posner RG.

BMC Syst Biol. 2012 Aug 22;6:107. doi: 10.1186/1752-0509-6-107.


Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations.

Nandakumar V, Kelbauskas L, Hernandez KF, Lintecum KM, Senechal P, Bussey KJ, Davies PC, Johnson RH, Meldrum DR.

PLoS One. 2012;7(1):e29230. doi: 10.1371/journal.pone.0029230. Epub 2012 Jan 5.


Targeted therapies for adrenocortical carcinoma: IGF and beyond.

Demeure MJ, Bussey KJ, Kirschner LS.

Horm Cancer. 2011 Dec;2(6):385-92. doi: 10.1007/s12672-011-0090-6. Review.


Preclinical investigation of nanoparticle albumin-bound paclitaxel as a potential treatment for adrenocortical cancer.

Demeure MJ, Stephan E, Sinari S, Mount D, Gately S, Gonzales P, Hostetter G, Komorowski R, Kiefer J, Grant CS, Han H, Von Hoff DD, Bussey KJ.

Ann Surg. 2012 Jan;255(1):140-6. doi: 10.1097/SLA.0b013e3182402d21.


Genomic signatures of cancer: basis for individualized risk assessment, selective staging and therapy.

Baehner FL, Lee M, Demeure MJ, Bussey KJ, Kiefer JA, Barrett MT.

J Surg Oncol. 2011 May 1;103(6):563-73. doi: 10.1002/jso.21838. Review.


Toward a pathway-centered approach for the treatment of adrenocortical carcinoma.

Bussey KJ, Demeure MJ.

Curr Opin Oncol. 2011 Jan;23(1):34-44. doi: 10.1097/CCO.0b013e328340d879. Review.


Multi-institutional tumor banking: lessons learned from a pancreatic cancer biospecimen repository.

Demeure MJ, Sielaff T, Koep L, Prinz R, Moser AJ, Zeh H 3rd, Hostetter G, Black J, Decker A, Rosewell S, Bussey KJ, Von Hoff D.

Pancreas. 2010 Oct;39(7):949-54. doi: 10.1097/MPA.0b013e3181df27a8. Review.


Multifactorial regulation of E-cadherin expression: an integrative study.

Reinhold WC, Reimers MA, Lorenzi P, Ho J, Shankavaram UT, Ziegler MS, Bussey KJ, Nishizuka S, Ikediobi O, Pommier YG, Weinstein JN.

Mol Cancer Ther. 2010 Jan;9(1):1-16. doi: 10.1158/1535-7163.MCT-09-0321. Epub 2010 Jan 6.


Adrenocortical cancer.

Wandoloski M, Bussey KJ, Demeure MJ.

Surg Clin North Am. 2009 Oct;89(5):1255-67. doi: 10.1016/j.suc.2009.06.019. Review.


Genomic and expression profiling of adrenocortical carcinoma: application to diagnosis, prognosis and treatment.

Bussey KJ, Demeure MJ.

Future Oncol. 2009 Jun;5(5):641-55. doi: 10.2217/fon.09.45. Review.


Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.

Lorenzi PL, Reinhold WC, Rudelius M, Gunsior M, Shankavaram U, Bussey KJ, Scherf U, Eichler GS, Martin SE, Chin K, Gray JW, Kohn EC, Horak ID, Von Hoff DD, Raffeld M, Goldsmith PK, Caplen NJ, Weinstein JN.

Mol Cancer Ther. 2006 Nov;5(11):2613-23. Epub 2006 Nov 6.


Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.

Bussey KJ, Chin K, Lababidi S, Reimers M, Reinhold WC, Kuo WL, Gwadry F, Ajay, Kouros-Mehr H, Fridlyand J, Jain A, Collins C, Nishizuka S, Tonon G, Roschke A, Gehlhaus K, Kirsch I, Scudiero DA, Gray JW, Weinstein JN.

Mol Cancer Ther. 2006 Apr;5(4):853-67.


Predicting drug sensitivity and resistance: profiling ABC transporter genes in cancer cells.

Szakács G, Annereau JP, Lababidi S, Shankavaram U, Arciello A, Bussey KJ, Reinhold W, Guo Y, Kruh GD, Reimers M, Weinstein JN, Gottesman MM.

Cancer Cell. 2004 Aug;6(2):129-37.


Mistaken identifiers: gene name errors can be introduced inadvertently when using Excel in bioinformatics.

Zeeberg BR, Riss J, Kane DW, Bussey KJ, Uchio E, Linehan WM, Barrett JC, Weinstein JN.

BMC Bioinformatics. 2004 Jun 23;5:80.


Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance.

Huang Y, Anderle P, Bussey KJ, Barbacioru C, Shankavaram U, Dai Z, Reinhold WC, Papp A, Weinstein JN, Sadée W.

Cancer Res. 2004 Jun 15;64(12):4294-301.

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