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Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches.

Lund-Palau H, Turnbull AR, Bush A, Bardin E, Cameron L, Soren O, Wierre-Gore N, Alton EW, Bundy JG, Connett G, Faust SN, Filloux A, Freemont P, Jones A, Khoo V, Morales S, Murphy R, Pabary R, Simbo A, Schelenz S, Takats Z, Webb J, Williams HD, Davies JC.

Expert Rev Respir Med. 2016 Jun;10(6):685-97. doi: 10.1080/17476348.2016.1177460. Epub 2016 May 13.


Statistical Correlations between NMR Spectroscopy and Direct Infusion FT-ICR Mass Spectrometry Aid Annotation of Unknowns in Metabolomics.

Hao J, Liebeke M, Sommer U, Viant MR, Bundy JG, Ebbels TM.

Anal Chem. 2016 Mar 1;88(5):2583-9. doi: 10.1021/acs.analchem.5b02889. Epub 2016 Feb 10.


Identification of the Elusive Pyruvate Reductase of Chlamydomonas reinhardtii Chloroplasts.

Burgess SJ, Taha H, Yeoman JA, Iamshanova O, Chan KX, Boehm M, Behrends V, Bundy JG, Bialek W, Murray JW, Nixon PJ.

Plant Cell Physiol. 2016 Jan;57(1):82-94. doi: 10.1093/pcp/pcv167. Epub 2015 Nov 15.


Influence of the Crc regulator on the hierarchical use of carbon sources from a complete medium in Pseudomonas.

La Rosa R, Behrends V, Williams HD, Bundy JG, Rojo F.

Environ Microbiol. 2016 Mar;18(3):807-18. doi: 10.1111/1462-2920.13126. Epub 2016 Jan 18.


Metabolic Youth in Middle Age: Predicting Aging in Caenorhabditis elegans Using Metabolomics.

Davies SK, Bundy JG, Leroi AM.

J Proteome Res. 2015 Nov 6;14(11):4603-9. doi: 10.1021/acs.jproteome.5b00442. Epub 2015 Oct 13.


Unique metabolites protect earthworms against plant polyphenols.

Liebeke M, Strittmatter N, Fearn S, Morgan AJ, Kille P, Fuchser J, Wallis D, Palchykov V, Robertson J, Lahive E, Spurgeon DJ, McPhail D, Takáts Z, Bundy JG.

Nat Commun. 2015 Aug 4;6:7869. doi: 10.1038/ncomms8869.


Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype.

Lewis A, Mehta S, Hanna LN, Rogalski LA, Jeffery R, Nijhuis A, Kumagai T, Biancheri P, Bundy JG, Bishop CL, Feakins R, Di Sabatino A, Lee JC, Lindsay JO, Silver A.

Inflamm Bowel Dis. 2015 Aug;21(8):1926-34. doi: 10.1097/MIB.0000000000000443.


Translational arrest due to cytoplasmic redox stress delays adaptation to growth on methanol and heterologous protein expression in a typical fed-batch culture of Pichia pastoris.

Edwards-Jones B, Aw R, Barton GR, Tredwell GD, Bundy JG, Leak DJ.

PLoS One. 2015 Mar 18;10(3):e0119637. doi: 10.1371/journal.pone.0119637. eCollection 2015.


Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye.

Thompson RB, Reffatto V, Bundy JG, Kortvely E, Flinn JM, Lanzirotti A, Jones EA, McPhail DS, Fearn S, Boldt K, Ueffing M, Ratu SG, Pauleikhoff L, Bird AC, Lengyel I.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1565-70. doi: 10.1073/pnas.1413347112. Epub 2015 Jan 20. Erratum in: Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3971.


Identifying biochemical phenotypic differences between cryptic species.

Liebeke M, Bruford MW, Donnelly RK, Ebbels TM, Hao J, Kille P, Lahive E, Madison RM, Morgan AJ, Pinto-Juma GA, Spurgeon DJ, Svendsen C, Bundy JG.

Biol Lett. 2014 Sep;10(9). pii: 20140615. doi: 10.1098/rsbl.2014.0615.


A metabolic trade-off between phosphate and glucose utilization in Escherichia coli.

Behrends V, Maharjan RP, Ryall B, Feng L, Liu B, Wang L, Bundy JG, Ferenci T.

Mol Biosyst. 2014 Nov;10(11):2820-2. doi: 10.1039/c4mb00313f.


Metabolites and metals in Metazoa--what role do phytochelatins play in animals?

Bundy JG, Kille P.

Metallomics. 2014 Sep;6(9):1576-82. doi: 10.1039/c4mt00078a. Review.


Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN.

Hao J, Liebeke M, Astle W, De Iorio M, Bundy JG, Ebbels TM.

Nat Protoc. 2014;9(6):1416-27. doi: 10.1038/nprot.2014.090. Epub 2014 May 22.


Metabolic footprinting: extracellular metabolomic analysis.

Behrends V, Williams HD, Bundy JG.

Methods Mol Biol. 2014;1149:281-92. doi: 10.1007/978-1-4939-0473-0_23.


Phenylalanine metabolism regulates reproduction and parasite melanization in the malaria mosquito.

Fuchs S, Behrends V, Bundy JG, Crisanti A, Nolan T.

PLoS One. 2014 Jan 7;9(1):e84865. doi: 10.1371/journal.pone.0084865. eCollection 2014.


Metallothioneins may not be enough--the role of phytochelatins in invertebrate metal detoxification.

Bundy JG, Kille P, Liebeke M, Spurgeon DJ.

Environ Sci Technol. 2014 Jan 21;48(2):885-6. doi: 10.1021/es4054779. Epub 2013 Dec 26. No abstract available.


Earthworms produce phytochelatins in response to arsenic.

Liebeke M, Garcia-Perez I, Anderson CJ, Lawlor AJ, Bennett MH, Morris CA, Kille P, Svendsen C, Spurgeon DJ, Bundy JG.

PLoS One. 2013 Nov 22;8(11):e81271. doi: 10.1371/journal.pone.0081271. eCollection 2013.


Nitrogen and carbon status are integrated at the transcriptional level by the nitrogen regulator NtrC in vivo.

Schumacher J, Behrends V, Pan Z, Brown DR, Heydenreich F, Lewis MR, Bennett MH, Razzaghi B, Komorowski M, Barahona M, Stumpf MP, Wigneshweraraj S, Bundy JG, Buck M.

MBio. 2013 Nov 19;4(6):e00881-13. doi: 10.1128/mBio.00881-13.


Analysis of intact bacteria using rapid evaporative ionisation mass spectrometry.

Strittmatter N, Jones EA, Veselkov KA, Rebec M, Bundy JG, Takats Z.

Chem Commun (Camb). 2013 Jul 14;49(55):6188-90. doi: 10.1039/c3cc42015a.


Metabolite profiling to characterize disease-related bacteria: gluconate excretion by Pseudomonas aeruginosa mutants and clinical isolates from cystic fibrosis patients.

Behrends V, Bell TJ, Liebeke M, Cordes-Blauert A, Ashraf SN, Nair C, Zlosnik JE, Williams HD, Bundy JG.

J Biol Chem. 2013 May 24;288(21):15098-109. doi: 10.1074/jbc.M112.442814. Epub 2013 Apr 9.

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