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Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts.

Burel SA, Hart CE, Cauntay P, Hsiao J, Machemer T, Katz M, Watt A, Bui HH, Younis H, Sabripour M, Freier SM, Hung G, Dan A, Prakash TP, Seth PP, Swayze EE, Bennett CF, Crooke ST, Henry SP.

Nucleic Acids Res. 2015 Nov 8. pii: gkv1210. [Epub ahead of print]


Pyrolysis of microalgae residues - A kinetic study.

Bui HH, Tran KQ, Chen WH.

Bioresour Technol. 2016 Jan;199:362-6. doi: 10.1016/j.biortech.2015.08.069. Epub 2015 Aug 28.


An Integrative Analysis of Foot-and-Mouth Disease Virus Carriers in Vietnam Achieved Through Targeted Surveillance and Molecular Epidemiology.

de Carvalho Ferreira HC, Pauszek SJ, Ludi A, Huston CL, Pacheco JM, Le VT, Nguyen PT, Bui HH, Nguyen TD, Nguyen T, Nguyen TT, Ngo LT, Do DH, Rodriguez L, Arzt J.

Transbound Emerg Dis. 2015 Aug 24. doi: 10.1111/tbed.12403. [Epub ahead of print]


Deficiency in Lysophosphatidylcholine Acyltransferase 3 Reduces Plasma Levels of Lipids by Reducing Lipid Absorption in Mice.

Li Z, Jiang H, Ding T, Lou C, Bui HH, Kuo MS, Jiang XC.

Gastroenterology. 2015 Nov;149(6):1519-29. doi: 10.1053/j.gastro.2015.07.012. Epub 2015 Jul 27.


TGFβ-Mediated induction of SphK1 as a potential determinant in human MDA-MB-231 breast cancer cell bone metastasis.

Stayrook KR, Mack JK, Cerabona D, Edwards DF, Bui HH, Niewolna M, Fournier PG, Mohammad KS, Waning DL, Guise TA.

Bonekey Rep. 2015 Jul 8;4:719. doi: 10.1038/bonekey.2015.88. eCollection 2015.


Serum sphingolipids: relationships to insulin sensitivity and changes with exercise in humans.

Bergman BC, Brozinick JT, Strauss A, Bacon S, Kerege A, Bui HH, Sanders P, Siddall P, Kuo MS, Perreault L.

Am J Physiol Endocrinol Metab. 2015 Aug 15;309(4):E398-408. doi: 10.1152/ajpendo.00134.2015. Epub 2015 Jun 30.


Sphingosine-1-Phosphate Is a Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity.

Malik FA, Meissner A, Semenkov I, Molinski S, Pasyk S, Ahmadi S, Bui HH, Bear CE, Lidington D, Bolz SS.

PLoS One. 2015 Jun 16;10(6):e0130313. doi: 10.1371/journal.pone.0130313. eCollection 2015.


Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8 Through Investigations of TARP γ-8 Null Mice§.

Gleason SD, Kato A, Bui HH, Thompson LK, Valli SN, Stutz PV, Kuo MS, Falcone JF, Anderson WH, Li X, Witkin JM.

CNS Neurol Disord Drug Targets. 2015;14(5):612-26.


Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.

Vickers TA, Freier SM, Bui HH, Watt A, Crooke ST.

PLoS One. 2014 Oct 15;9(10):e110615. doi: 10.1371/journal.pone.0110615. eCollection 2014.


Identification of REST-regulated genes and pathways using a REST-targeted antisense approach.

Sedaghat Y, Bui HH, Mazur C, Monia BP.

Nucleic Acid Ther. 2013 Dec;23(6):389-400. doi: 10.1089/nat.2013.0445.


An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice.

Holland WL, Adams AC, Brozinick JT, Bui HH, Miyauchi Y, Kusminski CM, Bauer SM, Wade M, Singhal E, Cheng CC, Volk K, Kuo MS, Gordillo R, Kharitonenkov A, Scherer PE.

Cell Metab. 2013 May 7;17(5):790-7. doi: 10.1016/j.cmet.2013.03.019.


Regulation of GPR119 receptor activity with endocannabinoid-like lipids.

Syed SK, Bui HH, Beavers LS, Farb TB, Ficorilli J, Chesterfield AK, Kuo MS, Bokvist K, Barrett DG, Efanov AM.

Am J Physiol Endocrinol Metab. 2012 Dec 15;303(12):E1469-78. doi: 10.1152/ajpendo.00269.2012. Epub 2012 Oct 16.


Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice.

Li Z, Fan Y, Liu J, Li Y, Huan C, Bui HH, Kuo MS, Park TS, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1577-84. doi: 10.1161/ATVBAHA.112.251538. Epub 2012 May 10.


Analysis of sphingolipids in extracted human plasma using liquid chromatography electrospray ionization tandem mass spectrometry.

Bui HH, Leohr JK, Kuo MS.

Anal Biochem. 2012 Apr 15;423(2):187-94. doi: 10.1016/j.ab.2012.01.027. Epub 2012 Jan 31.


Reducing plasma membrane sphingomyelin increases insulin sensitivity.

Li Z, Zhang H, Liu J, Liang CP, Li Y, Li Y, Teitelman G, Beyer T, Bui HH, Peake DA, Zhang Y, Sanders PE, Kuo MS, Park TS, Cao G, Jiang XC.

Mol Cell Biol. 2011 Oct;31(20):4205-18. doi: 10.1128/MCB.05893-11. Epub 2011 Aug 15.


Modeling of the water network at protein-RNA interfaces.

Li Y, Sutch BT, Bui HH, Gallaher TK, Haworth IS.

J Chem Inf Model. 2011 Jun 27;51(6):1347-52. doi: 10.1021/ci200118y. Epub 2011 Jun 7.


Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE.

Nat Med. 2011 Jan;17(1):55-63. doi: 10.1038/nm.2277. Epub 2010 Dec 26.


Selective reduction in the sphingomyelin content of atherogenic lipoproteins inhibits their retention in murine aortas and the subsequent development of atherosclerosis.

Fan Y, Shi F, Liu J, Dong J, Bui HH, Peake DA, Kuo MS, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2114-20. doi: 10.1161/ATVBAHA.110.213363. Epub 2010 Sep 2.


Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage.

Kotturi MF, Botten J, Maybeno M, Sidney J, Glenn J, Bui HH, Oseroff C, Crotty S, Peters B, Grey H, Altmann DM, Buchmeier MJ, Sette A.

Immunome Res. 2010 May 17;6:4. doi: 10.1186/1745-7580-6-4.


A multivalent and cross-protective vaccine strategy against arenaviruses associated with human disease.

Kotturi MF, Botten J, Sidney J, Bui HH, Giancola L, Maybeno M, Babin J, Oseroff C, Pasquetto V, Greenbaum JA, Peters B, Ting J, Do D, Vang L, Alexander J, Grey H, Buchmeier MJ, Sette A.

PLoS Pathog. 2009 Dec;5(12):e1000695. doi: 10.1371/journal.ppat.1000695. Epub 2009 Dec 18.

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