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Results: 1 to 20 of 80


Induction of homologous recombination between sequence repeats by the activation induced cytidine deaminase (AID) protein.

Buerstedde JM, Lowndes N, Schatz DG.

Elife. 2014 Jul 8;3:e03110. doi: 10.7554/eLife.03110.


Targeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences.

Buerstedde JM, Alinikula J, Arakawa H, McDonald JJ, Schatz DG.

PLoS Biol. 2014 Apr 1;12(4):e1001831. doi: 10.1371/journal.pbio.1001831. eCollection 2014 Apr.


Directed evolution of an angiopoietin-2 ligand trap by somatic hypermutation and cell surface display.

Brindle NP, Sale JE, Arakawa H, Buerstedde JM, Nuamchit T, Sharma S, Steele KH.

J Biol Chem. 2013 Nov 15;288(46):33205-12. doi: 10.1074/jbc.M113.510578. Epub 2013 Oct 8.


A critical context-dependent role for E boxes in the targeting of somatic hypermutation.

McDonald JJ, Alinikula J, Buerstedde JM, Schatz DG.

J Immunol. 2013 Aug 15;191(4):1556-66. doi: 10.4049/jimmunol.1300969. Epub 2013 Jul 8.


Identification of core DNA elements that target somatic hypermutation.

Kohler KM, McDonald JJ, Duke JL, Arakawa H, Tan S, Kleinstein SH, Buerstedde JM, Schatz DG.

J Immunol. 2012 Dec 1;189(11):5314-26. doi: 10.4049/jimmunol.1202082. Epub 2012 Oct 19.


Understanding the immunoglobulin locus specificity of hypermutation.

Batrak V, Blagodatski A, Buerstedde JM.

Methods Mol Biol. 2011;745:311-26. doi: 10.1007/978-1-61779-129-1_18.


A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation.

Blagodatski A, Batrak V, Schmidl S, Schoetz U, Caldwell RB, Arakawa H, Buerstedde JM.

PLoS Genet. 2009 Jan;5(1):e1000332. doi: 10.1371/journal.pgen.1000332. Epub 2009 Jan 9.


Activation-induced cytidine deaminase-mediated hypermutation in the DT40 cell line.

Arakawa H, Buerstedde JM.

Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):639-44. doi: 10.1098/rstb.2008.0202. Review.


The 9-1-1 DNA clamp is required for immunoglobulin gene conversion.

Saberi A, Nakahara M, Sale JE, Kikuchi K, Arakawa H, Buerstedde JM, Yamamoto K, Takeda S, Sonoda E.

Mol Cell Biol. 2008 Oct;28(19):6113-22. doi: 10.1128/MCB.00156-08. Epub 2008 Jul 28.


Gene function analysis using the chicken B-cell line DT40.

Caldwell RB, Fiedler P, Schoetz U, Buerstedde JM.

Methods Mol Biol. 2007;408:193-210. doi: 10.1007/978-1-59745-547-3_11.


Protein evolution by hypermutation and selection in the B cell line DT40.

Arakawa H, Kudo H, Batrak V, Caldwell RB, Rieger MA, Ellwart JW, Buerstedde JM.

Nucleic Acids Res. 2008 Jan;36(1):e1. Epub 2007 Dec 11.


Dependence of antibody gene diversification on uracil excision.

Di Noia JM, Williams GT, Chan DT, Buerstedde JM, Baldwin GS, Neuberger MS.

J Exp Med. 2007 Dec 24;204(13):3209-19. Epub 2007 Dec 10.


Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.

Ridpath JR, Nakamura A, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde JM, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA, Nakamura J.

Cancer Res. 2007 Dec 1;67(23):11117-22.


Subcellular distribution of human RDM1 protein isoforms and their nucleolar accumulation in response to heat shock and proteotoxic stress.

Messaoudi L, Yang YG, Kinomura A, Stavreva DA, Yan G, Bortolin-Cavaillé ML, Arakawa H, Buerstedde JM, Hainaut P, Cavaillé J, Takata M, Van Dyck E.

Nucleic Acids Res. 2007;35(19):6571-87. Epub 2007 Sep 28.


Biotechnology and the chicken B cell line DT40.

Bachl J, Caldwell RB, Buerstedde JM.

Cytogenet Genome Res. 2007;117(1-4):189-94.


Subcloning Dt40 by limiting dilution.

Buerstedde JM.

Subcell Biochem. 2006;40:393-4.


Immunoglobulin gene conversion or hypermutation: that's the question.

Buerstedde JM, Arakawa H.

Subcell Biochem. 2006;40:11-24. Review.


Dt40 gene disruptions: a how-to for the design and the construction of targeting vectors.

Arakawa H, Buerstedde JM.

Subcell Biochem. 2006;40:1-9. Review.


Interplay between DNA polymerases beta and lambda in repair of oxidation DNA damage in chicken DT40 cells.

Tano K, Nakamura J, Asagoshi K, Arakawa H, Sonoda E, Braithwaite EK, Prasad R, Buerstedde JM, Takeda S, Watanabe M, Wilson SH.

DNA Repair (Amst). 2007 Jun 1;6(6):869-75. Epub 2007 Mar 23.


RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.

Saberi A, Hochegger H, Szuts D, Lan L, Yasui A, Sale JE, Taniguchi Y, Murakawa Y, Zeng W, Yokomori K, Helleday T, Teraoka H, Arakawa H, Buerstedde JM, Takeda S.

Mol Cell Biol. 2007 Apr;27(7):2562-71. Epub 2007 Jan 22.

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