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Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan.

Fu Y, Zhao J, Atagi Y, Nielsen HM, Liu CC, Zheng H, Shinohara M, Kanekiyo T, Bu G.

Mol Neurodegener. 2016 May 5;11(1):37. doi: 10.1186/s13024-016-0099-y.


Implications of GABAergic Neurotransmission in Alzheimer's Disease.

Li Y, Sun H, Chen Z, Xu H, Bu G, Zheng H.

Front Aging Neurosci. 2016 Feb 23;8:31. doi: 10.3389/fnagi.2016.00031. eCollection 2016. Review.


Apolipoprotein E epsilon 2 allele and low serum cholesterol as risk factors for gastric cancer in a Chinese Han population.

Kang R, Li P, Wang T, Li X, Wei Z, Zhang Z, Zhong L, Cao L, Heckman MG, Zhang YW, Xu H, Huang C, Bu G, Chen XF.

Sci Rep. 2016 Jan 28;6:19930. doi: 10.1038/srep19930.


Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells.

Reynolds MR, Singh I, Azad TD, Holmes BB, Verghese PB, Dietrich HH, Diamond M, Bu G, Han BH, Zipfel GJ.

Mol Neurodegener. 2016 Jan 22;11:9. doi: 10.1186/s13024-016-0073-8.


Association of follistatin-like 3 concentrations in serum and synovial fluid with the radiographic severity of knee osteoarthritis.

Liu G, Chen S, Deng S, Ma X, Hao Y, Bu G.

Int J Clin Exp Med. 2015 Oct 15;8(10):18884-8. eCollection 2015.


A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism.

Zhong L, Xie YZ, Cao TT, Wang Z, Wang T, Li X, Shen RC, Xu H, Bu G, Chen XF.

Mol Neurodegener. 2016 Jan 12;11:2. doi: 10.1186/s13024-016-0069-4.


The Expression of Porcine Prdx6 Gene Is Up-Regulated by C/EBPβ and CREB.

Wu X, Ji P, Zhang L, Bu G, Gu H, Wang X, Xiong Y, Zuo B.

PLoS One. 2015 Dec 14;10(12):e0144851. doi: 10.1371/journal.pone.0144851. eCollection 2015.


Demographic and Lifestyle Characteristics, but Not Apolipoprotein E Genotype, Are Associated with Intelligence among Young Chinese College Students.

Chen XF, Wei Z, Wang T, Zhang ZL, Wang Y, Heckman MG, Diehl NN, Zhang YW, Xu H, Bu G.

PLoS One. 2015 Nov 17;10(11):e0143157. doi: 10.1371/journal.pone.0143157. eCollection 2015.


Genetics ignite focus on microglial inflammation in Alzheimer's disease.

Malik M, Parikh I, Vasquez JB, Smith C, Tai L, Bu G, LaDu MJ, Fardo DW, Rebeck GW, Estus S.

Mol Neurodegener. 2015 Oct 5;10:52. doi: 10.1186/s13024-015-0048-1.


Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.

Wren MC, Zhao J, Liu CC, Murray ME, Atagi Y, Davis MD, Fu Y, Okano HJ, Ogaki K, Strongosky AJ, Tacik P, Rademakers R, Ross OA, Dickson DW, Wszolek ZK, Kanekiyo T, Bu G.

Mol Neurodegener. 2015 Sep 15;10:46. doi: 10.1186/s13024-015-0042-7.


TREM2 in CNS homeostasis and neurodegenerative disease.

Painter MM, Atagi Y, Liu CC, Rademakers R, Xu H, Fryer JD, Bu G.

Mol Neurodegener. 2015 Sep 4;10:43. doi: 10.1186/s13024-015-0040-9. Review.


Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model.

Cook C, Kang SS, Carlomagno Y, Lin WL, Yue M, Kurti A, Shinohara M, Jansen-West K, Perkerson E, Castanedes-Casey M, Rousseau L, Phillips V, Bu G, Dickson DW, Petrucelli L, Fryer JD.

Hum Mol Genet. 2015 Nov 1;24(21):6198-212. doi: 10.1093/hmg/ddv336. Epub 2015 Aug 13.


Detection and enumeration of circulating tumor cells based on their invasive property.

Wang H, Hara Y, Liu X, Reuben JM, Xie Y, Xu H, Bu G, Pei Y, Gupta V, Wu X.

Oncotarget. 2015 Sep 29;6(29):27304-11. doi: 10.18632/oncotarget.4454.


Modulation of mitochondrial complex I activity averts cognitive decline in multiple animal models of familial Alzheimer's Disease.

Zhang L, Zhang S, Maezawa I, Trushin S, Minhas P, Pinto M, Jin LW, Prasain K, Nguyen TD, Yamazaki Y, Kanekiyo T, Bu G, Gateno B, Chang KO, Nath KA, Nemutlu E, Dzeja P, Pang YP, Hua DH, Trushina E.

EBioMedicine. 2015 Apr 1;2(4):294-305.


Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV.

Nat Neurosci. 2015 Jul;18(7):978-87. doi: 10.1038/nn.4025. Epub 2015 May 25.


DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response.

Zhong L, Chen XF, Zhang ZL, Wang Z, Shi XZ, Xu K, Zhang YW, Xu H, Bu G.

J Biol Chem. 2015 Jun 19;290(25):15866-77. doi: 10.1074/jbc.M115.645986. Epub 2015 May 8.


Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway.

Casey CS, Atagi Y, Yamazaki Y, Shinohara M, Tachibana M, Fu Y, Bu G, Kanekiyo T.

J Biol Chem. 2015 May 29;290(22):14208-17. doi: 10.1074/jbc.M114.625251. Epub 2015 Apr 22.


Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain.

Liu CC, Hu J, Tsai CW, Yue M, Melrose HL, Kanekiyo T, Bu G.

J Neurosci. 2015 Apr 8;35(14):5851-9. doi: 10.1523/JNEUROSCI.5180-14.2015.


Association between Virulence Factors and TRAF1/4-1BB/Bcl-xL Expression in Gastric Mucosa Infected with Helicobacter pylori.

Wang F, Wu X, Liu Z, Bu G, Li X, Qu N, Peng J, Xu C, Shen S, Yuan Y.

Gastroenterol Res Pract. 2015;2015:648479. doi: 10.1155/2015/648479. Epub 2015 Feb 8.

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