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Items: 1 to 20 of 81

1.

Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.

Zemanova J, Hylse O, Collakova J, Vesely P, Oltova A, Borsky M, Zaprazna K, Kasparkova M, Janovska P, Verner J, Kohoutek J, Dzimkova M, Bryja V, Jaskova Z, Brychtova Y, Paruch K, Trbusek M.

Oncotarget. 2016 Aug 19. doi: 10.18632/oncotarget.11388. [Epub ahead of print]

2.

Microenvironmental interactions between endothelial and lymphoma cells-a role for the canonical WNT pathway in Hodgkin lymphoma.

Linke F, Harenberg M, Nietert MM, Zaunig S, von Bonin F, Arlt A, Szczepanowski M, Weich HA, Lutz S, Dullin C, Janovská P, Krafčíková M, Trantírek L, Ovesná P, Klapper W, Beissbarth T, Alves F, Bryja V, Trümper L, Wilting J, Kube D.

Leukemia. 2016 Aug 18. doi: 10.1038/leu.2016.232. [Epub ahead of print]

PMID:
27535218
3.

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins.

Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, Bryja V.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9304-9. doi: 10.1073/pnas.1608783113. Epub 2016 Aug 2.

4.

WNT5A: a motility-promoting factor in Hodgkin lymphoma.

Linke F, Zaunig S, Nietert MM, von Bonin F, Lutz S, Dullin C, Janovská P, Beissbarth T, Alves F, Klapper W, Bryja V, Pukrop T, Trümper L, Wilting J, Kube D.

Oncogene. 2016 Jun 6. doi: 10.1038/onc.2016.183. [Epub ahead of print]

PMID:
27270428
5.

COBLL1, LPL and ZAP70 expression defines prognostic subgroups of chronic lymphocytic leukemia patients with high accuracy and correlates with IGHV mutational status.

Plesingerova H, Librova Z, Plevova K, Libra A, Tichy B, Skuhrova Francova H, Vrbacky F, Smolej L, Mayer J, Bryja V, Doubek M, Pospisilova S.

Leuk Lymphoma. 2016 May 17:1-10. [Epub ahead of print]

PMID:
27185377
6.

ROR1-based immunomagnetic protocol allows efficient separation of CLL and healthy B cells.

Kotašková J, Pavlová Š, Greif I, Stehlíková O, Plevová K, Janovská P, Brychtová Y, Doubek M, Pospíšilová Š, Bryja V.

Br J Haematol. 2015 Nov 16. doi: 10.1111/bjh.13848. [Epub ahead of print] No abstract available.

PMID:
26567475
7.

Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia.

Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, Pospisilova S, Pavlova S, Bryja V.

Clin Cancer Res. 2016 Jan 15;22(2):459-69. doi: 10.1158/1078-0432.CCR-15-0154. Epub 2015 Aug 3.

PMID:
26240275
8.

Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells.

Mo L, Pospichalova V, Huang Z, Murphy SK, Payne S, Wang F, Kennedy M, Cianciolo GJ, Bryja V, Pizzo SV, Bachelder RE.

PLoS One. 2015 Jul 6;10(7):e0131579. doi: 10.1371/journal.pone.0131579. eCollection 2015.

9.

Simplified protocol for flow cytometry analysis of fluorescently labeled exosomes and microvesicles using dedicated flow cytometer.

Pospichalova V, Svoboda J, Dave Z, Kotrbova A, Kaiser K, Klemova D, Ilkovics L, Hampl A, Crha I, Jandakova E, Minar L, Weinberger V, Bryja V.

J Extracell Vesicles. 2015 Mar 31;4:25530. doi: 10.3402/jev.v4.25530. eCollection 2015.

10.

Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex.

Ekumi KM, Paculova H, Lenasi T, Pospichalova V, Bösken CA, Rybarikova J, Bryja V, Geyer M, Blazek D, Barboric M.

Nucleic Acids Res. 2015 Mar 11;43(5):2575-89. doi: 10.1093/nar/gkv101. Epub 2015 Feb 20.

11.

Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway.

Kaucká M, Petersen J, Janovská P, Radaszkiewicz T, Smyčková L, Daulat AM, Borg JP, Schulte G, Bryja V.

Cell Commun Signal. 2015 Jan 28;13:2. doi: 10.1186/s12964-014-0079-1.

12.

Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage.

Buchtova M, Oralova V, Aklian A, Masek J, Vesela I, Ouyang Z, Obadalova T, Konecna Z, Spoustova T, Pospisilova T, Matula P, Varecha M, Balek L, Gudernova I, Jelinkova I, Duran I, Cervenkova I, Murakami S, Kozubik A, Dvorak P, Bryja V, Krejci P.

Biochim Biophys Acta. 2015 May;1852(5):839-50. doi: 10.1016/j.bbadis.2014.12.020. Epub 2015 Jan 2.

13.

Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5.

Bernatík O, Šedová K, Schille C, Ganji RS, Červenka I, Trantírek L, Schambony A, Zdráhal Z, Bryja V.

J Biol Chem. 2014 Aug 22;289(34):23520-33. doi: 10.1074/jbc.M114.590638. Epub 2014 Jul 3.

14.

Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway.

de Groot RE, Ganji RS, Bernatik O, Lloyd-Lewis B, Seipel K, Šedová K, Zdráhal Z, Dhople VM, Dale TC, Korswagen HC, Bryja V.

Sci Signal. 2014 Mar 18;7(317):ra26. doi: 10.1126/scisignal.2004985.

PMID:
24643799
15.

Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6.

Kilander MB, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G.

FASEB J. 2014 May;28(5):2293-305. doi: 10.1096/fj.13-246363. Epub 2014 Feb 5.

16.

β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation.

Seitz K, Dürsch V, Harnoš J, Bryja V, Gentzel M, Schambony A.

PLoS One. 2014 Jan 29;9(1):e87132. doi: 10.1371/journal.pone.0087132. eCollection 2014.

17.

β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein.

Kríz V, Pospíchalová V, Masek J, Kilander MB, Slavík J, Tanneberger K, Schulte G, Machala M, Kozubík A, Behrens J, Bryja V.

J Biol Chem. 2014 Jan 10;289(2):1128-41. doi: 10.1074/jbc.M113.498444. Epub 2013 Nov 21.

18.

The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling.

Soldano A, Okray Z, Janovska P, Tmejová K, Reynaud E, Claeys A, Yan J, Atak ZK, De Strooper B, Dura JM, Bryja V, Hassan BA.

PLoS Biol. 2013;11(5):e1001562. doi: 10.1371/journal.pbio.1001562. Epub 2013 May 14.

19.

The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration.

Kaucká M, Plevová K, Pavlová S, Janovská P, Mishra A, Verner J, Procházková J, Krejcí P, Kotasková J, Ovesná P, Tichy B, Brychtová Y, Doubek M, Kozubík A, Mayer J, Pospísilová S, Bryja V.

Cancer Res. 2013 Mar 1;73(5):1491-501. doi: 10.1158/0008-5472.CAN-12-1752. Epub 2013 Jan 21.

20.

Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells.

Andersson ER, Saltó C, Villaescusa JC, Cajanek L, Yang S, Bryjova L, Nagy II, Vainio SJ, Ramirez C, Bryja V, Arenas E.

Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):E602-10. doi: 10.1073/pnas.1208524110. Epub 2013 Jan 16.

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