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Results: 1 to 20 of 218

1.

Patient stratification and identification of adverse event correlations in the space of 1190 drug related adverse events.

Roitmann E, Eriksson R, Brunak S.

Front Physiol. 2014 Sep 9;5:332. doi: 10.3389/fphys.2014.00332. eCollection 2014.

PMID:
25249979
[PubMed]
Free PMC Article
2.

Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells.

Re A, Workman CT, Waldron L, Quattrone A, Brunak S.

Stem Cell Res. 2014 Sep;13(2):316-28. doi: 10.1016/j.scr.2014.07.008. Epub 2014 Aug 4.

PMID:
25173649
[PubMed - in process]
Free Article
3.

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.

Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sunagawa S, Plichta DR, Gautier L, Pedersen AG, Le Chatelier E, Pelletier E, Bonde I, Nielsen T, Manichanh C, Arumugam M, Batto JM, Quintanilha Dos Santos MB, Blom N, Borruel N, Burgdorf KS, Boumezbeur F, Casellas F, Doré J, Dworzynski P, Guarner F, Hansen T, Hildebrand F, Kaas RS, Kennedy S, Kristiansen K, Kultima JR, Léonard P, Levenez F, Lund O, Moumen B, Le Paslier D, Pons N, Pedersen O, Prifti E, Qin J, Raes J, Sørensen S, Tap J, Tims S, Ussery DW, Yamada T; MetaHIT Consortium, Renault P, Sicheritz-Ponten T, Bork P, Wang J, Brunak S, Ehrlich SD; MetaHIT Consortium.

Nat Biotechnol. 2014 Aug;32(8):822-8. doi: 10.1038/nbt.2939. Epub 2014 Jul 6.

PMID:
24997787
[PubMed - in process]
4.

An integrated catalog of reference genes in the human gut microbiome.

Li J, Jia H, Cai X, Zhong H, Feng Q, Sunagawa S, Arumugam M, Kultima JR, Prifti E, Nielsen T, Juncker AS, Manichanh C, Chen B, Zhang W, Levenez F, Wang J, Xu X, Xiao L, Liang S, Zhang D, Zhang Z, Chen W, Zhao H, Al-Aama JY, Edris S, Yang H, Wang J, Hansen T, Nielsen HB, Brunak S, Kristiansen K, Guarner F, Pedersen O, Doré J, Ehrlich SD; MetaHIT Consortium, Bork P, Wang J; MetaHIT Consortium.

Nat Biotechnol. 2014 Aug;32(8):834-41. doi: 10.1038/nbt.2942. Epub 2014 Jul 6.

PMID:
24997786
[PubMed - in process]
5.

Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients.

Wesołowska-Andersen A, Borst L, Dalgaard MD, Yadav R, Rasmussen KK, Wehner PS, Rasmussen M, Orntoft TF, Nordentoft I, Koehler R, Bartram CR, Schrappe M, Sicheritz-Ponten T, Gautier L, Marquart H, Madsen HO, Brunak S, Stanulla M, Gupta R, Schmiegelow K.

Leukemia. 2014 Jul 3. doi: 10.1038/leu.2014.205. [Epub ahead of print]

PMID:
24990611
[PubMed - as supplied by publisher]
6.

Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients.

Jensen AB, Moseley PL, Oprea TI, Ellesøe SG, Eriksson R, Schmock H, Jensen PB, Jensen LJ, Brunak S.

Nat Commun. 2014 Jun 24;5:4022. doi: 10.1038/ncomms5022.

PMID:
24959948
[PubMed - in process]
Free PMC Article
7.

Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics.

Lundby A, Rossin EJ, Steffensen AB, Acha MR, Newton-Cheh C, Pfeufer A, Lynch SN; QT Interval International GWAS Consortium (QT-IGC), Olesen SP, Brunak S, Ellinor PT, Jukema JW, Trompet S, Ford I, Macfarlane PW, Krijthe BP, Hofman A, Uitterlinden AG, Stricker BH, Nathoe HM, Spiering W, Daly MJ, Asselbergs FW, van der Harst P, Milan DJ, de Bakker PI, Lage K, Olsen JV.

Nat Methods. 2014 Aug;11(8):868-74. doi: 10.1038/nmeth.2997. Epub 2014 Jun 22.

PMID:
24952909
[PubMed - indexed for MEDLINE]
8.

Bacterial diversity in snow on North Pole ice floes.

Hauptmann AL, Stibal M, Bælum J, Sicheritz-Pontén T, Brunak S, Bowman JS, Hansen LH, Jacobsen CS, Blom N.

Extremophiles. 2014 Nov;18(6):945-51. doi: 10.1007/s00792-014-0660-y. Epub 2014 Jun 21.

PMID:
24951969
[PubMed - in process]
Free PMC Article
9.

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium.

Koivula RW, Heggie A, Barnett A, Cederberg H, Hansen TH, Koopman AD, Ridderstråle M, Rutters F, Vestergaard H, Gupta R, Herrgård S, Heymans MW, Perry MH, Rauh S, Siloaho M, Teare HJ, Thorand B, Bell J, Brunak S, Frost G, Jablonka B, Mari A, McDonald TJ, Dekker JM, Hansen T, Hattersley A, Laakso M, Pedersen O, Koivisto V, Ruetten H, Walker M, Pearson E, Franks PW; DIRECT Consortium.

Diabetologia. 2014 Jun;57(6):1132-42. doi: 10.1007/s00125-014-3216-x. Epub 2014 Apr 4.

PMID:
24695864
[PubMed - in process]
Free PMC Article
10.

Identification of odorant-receptor interactions by global mapping of the human odorome.

Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, Brunak S, Taboureau O.

PLoS One. 2014 Apr 2;9(4):e93037. doi: 10.1371/journal.pone.0093037. eCollection 2014.

PMID:
24695519
[PubMed - in process]
Free PMC Article
11.

Dose-specific adverse drug reaction identification in electronic patient records: temporal data mining in an inpatient psychiatric population.

Eriksson R, Werge T, Jensen LJ, Brunak S.

Drug Saf. 2014 Apr;37(4):237-47. doi: 10.1007/s40264-014-0145-z. Erratum in: Drug Saf. 2014 May;37(5):379.

PMID:
24634163
[PubMed - in process]
Free PMC Article
12.

Polychlorinated dibenzo-p-dioxins, furans, and biphenyls (PCDDs/PCDFs and PCBs) in breast milk and early childhood growth and IGF1.

Wohlfahrt-Veje C, Audouze K, Brunak S, Antignac JP, le Bizec B, Juul A, Skakkebæk NE, Main KM.

Reproduction. 2014 Mar 2;147(4):391-9. doi: 10.1530/REP-13-0422. Print 2014.

PMID:
24586095
[PubMed - in process]
13.

Cofactory: sequence-based prediction of cofactor specificity of Rossmann folds.

Geertz-Hansen HM, Blom N, Feist AM, Brunak S, Petersen TN.

Proteins. 2014 Sep;82(9):1819-28. doi: 10.1002/prot.24536. Epub 2014 Mar 20.

PMID:
24523134
[PubMed - in process]
14.

The genome of a Late Pleistocene human from a Clovis burial site in western Montana.

Rasmussen M, Anzick SL, Waters MR, Skoglund P, DeGiorgio M, Stafford TW Jr, Rasmussen S, Moltke I, Albrechtsen A, Doyle SM, Poznik GD, Gudmundsdottir V, Yadav R, Malaspinas AS, White SS 5th, Allentoft ME, Cornejo OE, Tambets K, Eriksson A, Heintzman PD, Karmin M, Korneliussen TS, Meltzer DJ, Pierre TL, Stenderup J, Saag L, Warmuth VM, Lopes MC, Malhi RS, Brunak S, Sicheritz-Ponten T, Barnes I, Collins M, Orlando L, Balloux F, Manica A, Gupta R, Metspalu M, Bustamante CD, Jakobsson M, Nielsen R, Willerslev E.

Nature. 2014 Feb 13;506(7487):225-9. doi: 10.1038/nature13025.

PMID:
24522598
[PubMed - indexed for MEDLINE]
15.

Compass: a hybrid method for clinical and biobank data mining.

Krysiak-Baltyn K, Nordahl Petersen T, Audouze K, Jørgensen N, Angquist L, Brunak S.

J Biomed Inform. 2014 Feb;47:160-70. doi: 10.1016/j.jbi.2013.10.007. Epub 2013 Oct 26.

PMID:
24513869
[PubMed - indexed for MEDLINE]
16.

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes.

Lohmueller KE, Sparsø T, Li Q, Andersson E, Korneliussen T, Albrechtsen A, Banasik K, Grarup N, Hallgrimsdottir I, Kiil K, Kilpeläinen TO, Krarup NT, Pers TH, Sanchez G, Hu Y, Degiorgio M, Jørgensen T, Sandbæk A, Lauritzen T, Brunak S, Kristiansen K, Li Y, Hansen T, Wang J, Nielsen R, Pedersen O.

Am J Hum Genet. 2013 Dec 5;93(6):1072-86. doi: 10.1016/j.ajhg.2013.11.005. Epub 2013 Nov 27. Erratum in: Am J Hum Genet. 2014 Mar 6;94(3):479.

PMID:
24290377
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans.

Raghavan M, Skoglund P, Graf KE, Metspalu M, Albrechtsen A, Moltke I, Rasmussen S, Stafford TW Jr, Orlando L, Metspalu E, Karmin M, Tambets K, Rootsi S, Mägi R, Campos PF, Balanovska E, Balanovsky O, Khusnutdinova E, Litvinov S, Osipova LP, Fedorova SA, Voevoda MI, DeGiorgio M, Sicheritz-Ponten T, Brunak S, Demeshchenko S, Kivisild T, Villems R, Nielsen R, Jakobsson M, Willerslev E.

Nature. 2014 Jan 2;505(7481):87-91. doi: 10.1038/nature12736. Epub 2013 Nov 20.

PMID:
24256729
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Bacterial natural transformation by highly fragmented and damaged DNA.

Overballe-Petersen S, Harms K, Orlando LA, Mayar JV, Rasmussen S, Dahl TW, Rosing MT, Poole AM, Sicheritz-Ponten T, Brunak S, Inselmann S, de Vries J, Wackernagel W, Pybus OG, Nielsen R, Johnsen PJ, Nielsen KM, Willerslev E.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19860-5. doi: 10.1073/pnas.1315278110. Epub 2013 Nov 18.

PMID:
24248361
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Metagenomic species profiling using universal phylogenetic marker genes.

Sunagawa S, Mende DR, Zeller G, Izquierdo-Carrasco F, Berger SA, Kultima JR, Coelho LP, Arumugam M, Tap J, Nielsen HB, Rasmussen S, Brunak S, Pedersen O, Guarner F, de Vos WM, Wang J, Li J, Doré J, Ehrlich SD, Stamatakis A, Bork P.

Nat Methods. 2013 Dec;10(12):1196-9. doi: 10.1038/nmeth.2693. Epub 2013 Oct 20.

PMID:
24141494
[PubMed - indexed for MEDLINE]
20.

A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.

Blair DR, Lyttle CS, Mortensen JM, Bearden CF, Jensen AB, Khiabanian H, Melamed R, Rabadan R, Bernstam EV, Brunak S, Jensen LJ, Nicolae D, Shah NH, Grossman RL, Cox NJ, White KP, Rzhetsky A.

Cell. 2013 Sep 26;155(1):70-80. doi: 10.1016/j.cell.2013.08.030.

PMID:
24074861
[PubMed - indexed for MEDLINE]
Free PMC Article

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