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Items: 1 to 20 of 210

1.

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia.

Cao L, McDonnell A, Nitzsche A, Alexandrou A, Saintot PP, Loucif AJ, Brown AR, Young G, Mis M, Randall A, Waxman SG, Stanley P, Kirby S, Tarabar S, Gutteridge A, Butt R, McKernan RM, Whiting P, Ali Z, Bilsland J, Stevens EB.

Sci Transl Med. 2016 Apr 20;8(335):335ra56. doi: 10.1126/scitranslmed.aad7653.

PMID:
27099175
2.

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release.

Alexandrou AJ, Brown AR, Chapman ML, Estacion M, Turner J, Mis MA, Wilbrey A, Payne EC, Gutteridge A, Cox PJ, Doyle R, Printzenhoff D, Lin Z, Marron BE, West C, Swain NA, Storer RI, Stupple PA, Castle NA, Hounshell JA, Rivara M, Randall A, Dib-Hajj SD, Krafte D, Waxman SG, Patel MK, Butt RP, Stevens EB.

PLoS One. 2016 Apr 6;11(4):e0152405. doi: 10.1371/journal.pone.0152405. eCollection 2016.

3.

During postnatal development endogenous neurosteroids influence GABA-ergic neurotransmission of mouse cortical neurons.

Brown AR, Mitchell SJ, Peden DR, Herd MB, Seifi M, Swinny JD, Belelli D, Lambert JJ.

Neuropharmacology. 2016 Apr;103:163-73. doi: 10.1016/j.neuropharm.2015.11.019. Epub 2015 Dec 2.

4.

Repurposed biological scaffolds: kidney to pancreas.

Willenberg BJ, Oca-Cossio J, Cai Y, Brown AR, Clapp WL, Abrahamson DR, Terada N, Ellison GW, Mathews CE, Batich CD, Ross EA.

Organogenesis. 2015;11(2):47-57. doi: 10.1080/15476278.2015.1067354.

5.

Krüppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling.

Brown AR, Simmen RC, Raj VR, Van TT, MacLeod SL, Simmen FA.

Carcinogenesis. 2015 Sep;36(9):946-55. doi: 10.1093/carcin/bgv104. Epub 2015 Jul 25.

PMID:
26210742
6.

Failure mode and effects analysis: a comparison of two common risk prioritisation methods.

McElroy LM, Khorzad R, Nannicelli AP, Brown AR, Ladner DP, Holl JL.

BMJ Qual Saf. 2016 May;25(5):329-36. doi: 10.1136/bmjqs-2015-004130. Epub 2015 Jul 13.

PMID:
26170336
7.

Phenotypic Characterisation of Shewanella oneidensis MR-1 Exposed to X-Radiation.

Brown AR, Correa E, Xu Y, AlMasoud N, Pimblott SM, Goodacre R, Lloyd JR.

PLoS One. 2015 Jun 22;10(6):e0131249. doi: 10.1371/journal.pone.0131249. eCollection 2015.

8.

A mass spectrometry-based assay for improved quantitative measurements of efflux pump inhibition.

Brown AR, Ettefagh KA, Todd D, Cole PS, Egan JM, Foil DH, Graf TN, Schindler BD, Kaatz GW, Cech NB.

PLoS One. 2015 May 11;10(5):e0124814. doi: 10.1371/journal.pone.0124814. eCollection 2015.

9.

Intracortical Microstimulation (ICMS) Activates Motor Cortex Layer 5 Pyramidal Neurons Mainly Transsynaptically.

Hussin AT, Boychuk JA, Brown AR, Pittman QJ, Teskey GC.

Brain Stimul. 2015 Jul-Aug;8(4):742-50. doi: 10.1016/j.brs.2015.03.003. Epub 2015 Mar 27.

PMID:
25892002
10.

The impact of gamma radiation on sediment microbial processes.

Brown AR, Boothman C, Pimblott SM, Lloyd JR.

Appl Environ Microbiol. 2015 Jun 15;81(12):4014-25. doi: 10.1128/AEM.00590-15. Epub 2015 Apr 3.

11.

Climate change and pollution speed declines in zebrafish populations.

Brown AR, Owen SF, Peters J, Zhang Y, Soffker M, Paull GC, Hosken DJ, Wahab MA, Tyler CR.

Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1237-46. doi: 10.1073/pnas.1416269112. Epub 2015 Mar 2.

12.

A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.

Payne CE, Brown AR, Theile JW, Loucif AJ, Alexandrou AJ, Fuller MD, Mahoney JH, Antonio BM, Gerlach AC, Printzenhoff DM, Prime RL, Stockbridge G, Kirkup AJ, Bannon AW, England S, Chapman ML, Bagal S, Roeloffs R, Anand U, Anand P, Bungay PJ, Kemp M, Butt RP, Stevens EB.

Br J Pharmacol. 2015 May;172(10):2654-70. doi: 10.1111/bph.13092. Epub 2015 Apr 10.

PMID:
25625641
13.

Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones.

Brown AR, Herd MB, Belelli D, Lambert JJ.

J Physiol. 2015 Jan 1;593(1):267-84. doi: 10.1113/jphysiol.2014.280263. Epub 2014 Dec 3.

15.

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β.

Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW.

Nat Commun. 2014 Nov 26;5:5513. doi: 10.1038/ncomms6513.

16.

Assessing variation in the potential susceptibility of fish to pharmaceuticals, considering evolutionary differences in their physiology and ecology.

Brown AR, Gunnarsson L, Kristiansson E, Tyler CR.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130576. doi: 10.1098/rstb.2013.0576.

17.

Medicating the environment: assessing risks of pharmaceuticals to wildlife and ecosystems.

Arnold KE, Brown AR, Ankley GT, Sumpter JP.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130569. doi: 10.1098/rstb.2013.0569.

18.

Enhanced gastrointestinal expression of cytosolic malic enzyme (ME1) induces intestinal and liver lipogenic gene expression and intestinal cell proliferation in mice.

Al-Dwairi A, Brown AR, Pabona JM, Van TH, Hamdan H, Mercado CP, Quick CM, Wight PA, Simmen RC, Simmen FA.

PLoS One. 2014 Nov 17;9(11):e113058. doi: 10.1371/journal.pone.0113058. eCollection 2014.

19.

Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones.

Brown AR, Herd MB, Belelli D, Lambert JJ.

J Physiol. 2014 Nov 10. [Epub ahead of print]

PMID:
25384774
20.

Motor cortex is functionally organized as a set of spatially distinct representations for complex movements.

Brown AR, Teskey GC.

J Neurosci. 2014 Oct 8;34(41):13574-85. doi: 10.1523/JNEUROSCI.2500-14.2014.

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