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Results: 1 to 20 of 38

1.

Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites.

Saunders NF, Brinkworth RI, Huber T, Kemp BE, Kobe B.

BMC Bioinformatics. 2008 May 26;9:245. doi: 10.1186/1471-2105-9-245.

2.

Protein kinases associated with the yeast phosphoproteome.

Brinkworth RI, Munn AL, Kobe B.

BMC Bioinformatics. 2006 Jan 31;7:47.

3.

Substrate specificity of protein kinases and computational prediction of substrates.

Kobe B, Kampmann T, Forwood JK, Listwan P, Brinkworth RI.

Biochim Biophys Acta. 2005 Dec 30;1754(1-2):200-9. Epub 2005 Sep 9. Review.

PMID:
16172032
4.

Structural basis for the specificity of bipartite nuclear localization sequence binding by importin-alpha.

Fontes MR, Teh T, Jans D, Brinkworth RI, Kobe B.

J Biol Chem. 2003 Jul 25;278(30):27981-7. Epub 2003 Apr 14.

5.

Structural basis and prediction of substrate specificity in protein serine/threonine kinases.

Brinkworth RI, Breinl RA, Kobe B.

Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):74-9. Epub 2002 Dec 26.

6.

A computational analysis of substrate binding strength by phosphorylase kinase and protein kinase A.

Brinkworth RI, Horne J, Kobe B.

J Mol Recognit. 2002 Mar-Apr;15(2):104-11.

PMID:
11954055
7.

Hemoglobin-degrading, aspartic proteases of blood-feeding parasites: substrate specificity revealed by homology models.

Brinkworth RI, Prociv P, Loukas A, Brindley PJ.

J Biol Chem. 2001 Oct 19;276(42):38844-51. Epub 2001 Aug 8.

8.

Proteolysis of human hemoglobin by schistosome cathepsin D.

Brindley PJ, Kalinna BH, Wong JY, Bogitsh BJ, King LT, Smyth DJ, Verity CK, Abbenante G, Brinkworth RI, Fairlie DP, Smythe ML, Milburn PJ, Bielefeldt-Ohmann H, Zheng Y, McManus DP.

Mol Biochem Parasitol. 2001 Jan 15;112(1):103-12.

PMID:
11166391
9.

Molecular modeling and substrate specificity of discrete cruzipain-like and cathepsin L-like cysteine proteinases of the human blood fluke Schistosoma mansoni.

Brady CP, Brinkworth RI, Dalton JP, Dowd AJ, Verity CK, Brindley PJ.

Arch Biochem Biophys. 2000 Aug 1;380(1):46-55.

PMID:
10900131
10.

Host specificity in blood feeding parasites: a defining contribution by haemoglobin-degrading enzymes?

Brinkworth RI, Harrop SA, Prociv P, Brindley PJ.

Int J Parasitol. 2000 May;30(6):785-90.

PMID:
10856514
11.

Phylogenetic relationships and theoretical model of human cathepsin W (lymphopain), a cysteine proteinase from cytotoxic T lymphocytes.

Brinkworth RI, Tort JF, Brindley PJ, Dalton JP.

Int J Biochem Cell Biol. 2000 Mar;32(3):373-84.

PMID:
10716634
12.

Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.

Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP.

Biochemistry. 1999 Jun 22;38(25):7978-88.

PMID:
10387041
13.

Homology model of the dengue 2 virus NS3 protease: putative interactions with both substrate and NS2B cofactor.

Brinkworth RI, Fairlie DP, Leung D, Young PR.

J Gen Virol. 1999 May;80 ( Pt 5):1167-77.

14.

Fine structure analysis of interaction of FcepsilonRI with IgE.

Hulett MD, Brinkworth RI, McKenzie IF, Hogarth PM.

J Biol Chem. 1999 May 7;274(19):13345-52.

15.

Structural analysis of the catalytic site of AcCP-1, a cysteine proteinase secreted by the hookworm Ancylostoma caninum.

Brinkworth RI, Brindley PJ, Harrop SA.

Biochim Biophys Acta. 1996 Nov 14;1298(1):4-8.

PMID:
8948483
16.

A novel substrate-binding pocket interaction restricts the specificity of the human NK cell-specific serine protease, Met-ase-1.

Smyth MJ, O'Connor MD, Trapani JA, Kershaw MH, Brinkworth RI.

J Immunol. 1996 Jun 1;156(11):4174-81.

PMID:
8666785
17.

Hydroxyquinones are competitive non-peptide inhibitors of HIV-1 proteinase.

Brinkworth RI, Fairlie DP.

Biochim Biophys Acta. 1995 Nov 15;1253(1):5-8.

PMID:
7492599
18.

Multiple regions of human Fc gamma RII (CD32) contribute to the binding of IgG.

Hulett MD, Witort E, Brinkworth RI, McKenzie IF, Hogarth PM.

J Biol Chem. 1995 Sep 8;270(36):21188-94.

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