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Retraction: The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling.

Gherzi R, Trabucchi M, Ponassi M, Ruggiero T, Corte G, Moroni C, Chen CY, Khabar KS, Andersen JS, Briata P.

PLoS Biol. 2015 Nov 16;13(11):e1002314. doi: 10.1371/journal.pbio.1002314. eCollection 2015 Nov. No abstract available.


H19 long noncoding RNA controls the mRNA decay promoting function of KSRP.

Giovarelli M, Bucci G, Ramos A, Bordo D, Wilusz CJ, Chen CY, Puppo M, Briata P, Gherzi R.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5023-8. doi: 10.1073/pnas.1415098111. Epub 2014 Nov 10.


KSRP controls pleiotropic cellular functions.

Gherzi R, Chen CY, Ramos A, Briata P.

Semin Cell Dev Biol. 2014 Oct;34:2-8. doi: 10.1016/j.semcdb.2014.05.004. Epub 2014 May 17. Review.


KSRP and MicroRNA 145 are negative regulators of lipolysis in white adipose tissue.

Lin YY, Chou CF, Giovarelli M, Briata P, Gherzi R, Chen CY.

Mol Cell Biol. 2014 Jun;34(12):2339-49. doi: 10.1128/MCB.00042-14. Epub 2014 Apr 14.


KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression.

Chou CF, Lin YY, Wang HK, Zhu X, Giovarelli M, Briata P, Gherzi R, Garvey WT, Chen CY.

Diabetes. 2014 Sep;63(9):2949-61. doi: 10.2337/db13-1901. Epub 2014 Apr 10.


KSRP silencing favors neural differentiation of P19 teratocarcinoma cells.

Giovarelli M, Bucci G, Pasero M, Gherzi R, Briata P.

Biochim Biophys Acta. 2013 May;1829(5):469-79. doi: 10.1016/j.bbagrm.2013.02.008. Epub 2013 Feb 24.


Functional and molecular insights into KSRP function in mRNA decay.

Briata P, Chen CY, Ramos A, Gherzi R.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):689-94. doi: 10.1016/j.bbagrm.2012.11.003. Epub 2012 Nov 22. Review.


Bone morphogenetic protein/SMAD signaling orients cell fate decision by impairing KSRP-dependent microRNA maturation.

Pasero M, Giovarelli M, Bucci G, Gherzi R, Briata P.

Cell Rep. 2012 Nov 29;2(5):1159-68. doi: 10.1016/j.celrep.2012.10.020. Epub 2012 Nov 21.


Noncanonical G recognition mediates KSRP regulation of let-7 biogenesis.

Nicastro G, García-Mayoral MF, Hollingworth D, Kelly G, Martin SR, Briata P, Gherzi R, Ramos A.

Nat Struct Mol Biol. 2012 Dec;19(12):1282-6. doi: 10.1038/nsmb.2427. Epub 2012 Nov 11.


Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.

Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M.

PLoS Genet. 2012;8(7):e1002823. doi: 10.1371/journal.pgen.1002823. Epub 2012 Jul 26.


KH domains with impaired nucleic acid binding as a tool for functional analysis.

Hollingworth D, Candel AM, Nicastro G, Martin SR, Briata P, Gherzi R, Ramos A.

Nucleic Acids Res. 2012 Aug;40(14):6873-86. doi: 10.1093/nar/gks368. Epub 2012 Apr 29.


The role of KSRP in mRNA decay and microRNA precursor maturation.

Gherzi R, Chen CY, Trabucchi M, Ramos A, Briata P.

Wiley Interdiscip Rev RNA. 2010 Sep-Oct;1(2):230-9. doi: 10.1002/wrna.2. Epub 2010 May 6. Review.


PI3K/AKT signaling determines a dynamic switch between distinct KSRP functions favoring skeletal myogenesis.

Briata P, Lin WJ, Giovarelli M, Pasero M, Chou CF, Trabucchi M, Rosenfeld MG, Chen CY, Gherzi R.

Cell Death Differ. 2012 Mar;19(3):478-87. doi: 10.1038/cdd.2011.117. Epub 2011 Sep 2.


KSRP Promotes the Maturation of a Group of miRNA Precuresors.

Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Adv Exp Med Biol. 2011;700:36-42. doi: 10.1007/978-1-4419-7823-3_4.


Autoregulatory circuit of human rpL3 expression requires hnRNP H1, NPM and KHSRP.

Russo A, Catillo M, Esposito D, Briata P, Pietropaolo C, Russo G.

Nucleic Acids Res. 2011 Sep 1;39(17):7576-85. doi: 10.1093/nar/gkr461. Epub 2011 Jun 25.


KSRP, many functions for a single protein.

Briata P, Chen CY, Giovarelli M, Pasero M, Trabucchi M, Ramos A, Gherzi R.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1787-96. Review.


Orientation of the central domains of KSRP and its implications for the interaction with the RNA targets.

Díaz-Moreno I, Hollingworth D, Kelly G, Martin S, García-Mayoral M, Briata P, Gherzi R, Ramos A.

Nucleic Acids Res. 2010 Aug;38(15):5193-205. doi: 10.1093/nar/gkq216. Epub 2010 Apr 12.


KSRP promotes the maturation of a group of miRNA precursors.

Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Adv Exp Med Biol. 2010;700:36-42.


Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.

Gherzi R, Trabucchi M, Ponassi M, Gallouzi IE, Rosenfeld MG, Briata P.

Cell Death Differ. 2010 Jun;17(6):975-83. doi: 10.1038/cdd.2009.194. Epub 2009 Dec 18.


How to control miRNA maturation?

Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R.

RNA Biol. 2009 Nov-Dec;6(5):536-40. Review.

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