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Items: 10

1.

Clinical efficacy of a new CD28-targeting antagonist of T cell co-stimulation in a non-human primate model of collagen-induced arthritis.

Vierboom MP, Breedveld E, Kap YS, Mary C, Poirier N, 't Hart BA, Vanhove B.

Clin Exp Immunol. 2016 Mar;183(3):405-18. doi: 10.1111/cei.12739. Epub 2015 Dec 16.

PMID:
26540618
2.

Safety, Biodistribution, and Efficacy of an AAV-5 Vector Encoding Human Interferon-Beta (ART-I02) Delivered via Intra-Articular Injection in Rhesus Monkeys with Collagen-Induced Arthritis.

Bevaart L, Aalbers CJ, Vierboom MP, Broekstra N, Kondova I, Breedveld E, Hauck B, Wright JF, Tak PP, Vervoordeldonk MJ.

Hum Gene Ther Clin Dev. 2015 Jun;26(2):103-12. doi: 10.1089/humc.2015.009.

PMID:
26086763
3.

The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis.

Van Roy M, Ververken C, Beirnaert E, Hoefman S, Kolkman J, Vierboom M, Breedveld E, 't Hart B, Poelmans S, Bontinck L, Hemeryck A, Jacobs S, Baumeister J, Ulrichts H.

Arthritis Res Ther. 2015 May 20;17:135. doi: 10.1186/s13075-015-0651-0.

4.

SAFETY, BIODISTRIBUTION, AND EFFICACY OF AN AAV-5 VECTOR ENCODING HUMAN INTERFERON-BETA (ART-I02) DELIVERED VIA INTRA-ARTICULAR INJECTION IN RHESUS MONKEYS WITH COLLAGEN-INDUCED ARTHRITIS.

Bevaart L, Aalbers CC, Vierboom M, Broekstra N, Kondova I, Breedveld E, Hauck B, Wright F, Tak PP, Vervoordeldonk MJ.

Hum Gene Ther Clin Dev. 2015 May 13. [Epub ahead of print]

PMID:
25970762
5.

PDL241, a novel humanized monoclonal antibody, reveals CD319 as a therapeutic target for rheumatoid arthritis.

Woo J, Vierboom MP, Kwon H, Chao D, Ye S, Li J, Lin K, Tang I, Belmar NA, Hartman T, Breedveld E, Vexler V, 't Hart BA, Law DA, Starling GC.

Arthritis Res Ther. 2013;15(6):R207.

6.

New drug discovery strategies for rheumatoid arthritis: a niche for nonhuman primate models to address systemic complications in inflammatory arthritis.

Vierboom M, Breedveld E, 't Hart BA.

Expert Opin Drug Discov. 2012 Apr;7(4):315-25. doi: 10.1517/17460441.2012.666523. Epub 2012 Feb 28. Review.

PMID:
22458503
7.

Collagen-induced arthritis in common marmosets: a new nonhuman primate model for chronic arthritis.

Vierboom MP, Breedveld E, Kondova I, 't Hart BA.

Arthritis Res Ther. 2010;12(5):R200. doi: 10.1186/ar3172. Epub 2010 Oct 26.

8.

Mitigation of septic shock in mice and rhesus monkeys by human chorionic gonadotrophin-related oligopeptides.

Khan NA, Vierboom MP, van Holten-Neelen C, Breedveld E, Zuiderwijk-Sick E, Khan A, Kondova I, Braskamp G, Savelkoul HF, Dik WA, 't Hart BA, Benner R.

Clin Exp Immunol. 2010 Jun;160(3):466-78. doi: 10.1111/j.1365-2249.2010.04112.x. Epub 2010 Mar 16.

9.

The significance of non-human primates as preclinical models of human arthritic disease.

Vierboom M, Breedveld E, Kondova I, 't Hart BA.

Expert Opin Drug Discov. 2008 Mar;3(3):299-310. doi: 10.1517/17460441.3.3.299.

PMID:
23480265
10.

Labour supply in the home care industry: A case study in a Dutch region.

Breedveld EJ, Meijboom BR, de Roo AA.

Health Policy. 2006 Apr;76(2):144-55. Epub 2005 Jul 11.

PMID:
16011857
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