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Results: 1 to 20 of 378

1.

Adenoassociated Virus Serotype 9-Mediated Gene Therapy for X-Linked Adrenoleukodystrophy.

Gong Y, Mu D, Prabhakar S, Moser A, Musolino P, Ren J, Breakefield XO, Maguire CA, Eichler FS.

Mol Ther. 2015 Jan 16. doi: 10.1038/mt.2015.6. [Epub ahead of print]

PMID:
25592337
2.

Emerging roles of extracellular vesicles in the nervous system.

Rajendran L, Bali J, Barr MM, Court FA, Krämer-Albers EM, Picou F, Raposo G, van der Vos KE, van Niel G, Wang J, Breakefield XO.

J Neurosci. 2014 Nov 12;34(46):15482-9. doi: 10.1523/JNEUROSCI.3258-14.2014. Review.

PMID:
25392515
3.

Therapeutic applications of extracellular vesicles: clinical promise and open questions.

György B, Hung ME, Breakefield XO, Leonard JN.

Annu Rev Pharmacol Toxicol. 2015;55:439-64. doi: 10.1146/annurev-pharmtox-010814-124630. Epub 2014 Oct 3.

PMID:
25292428
4.

New methods for investigation of neuronal migration in embryonic brain explants.

Nery FC, da Hora CC, Yaqub U, Zhang X, McCarthy DM, Bhide PG, Irimia D, Breakefield XO.

J Neurosci Methods. 2015 Jan 15;239:80-4. doi: 10.1016/j.jneumeth.2014.09.028. Epub 2014 Oct 5.

PMID:
25291524
5.

Update from the 2013 International Neurofibromatosis Conference.

Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, Parkinson DB, Stemmer-Rachamimov AO, Van Raamsdonk CD, Riccardi VM, Rosser T, Schindeler A, Smith MJ, Stevenson DA, Ullrich NJ, van der Vaart T, Weiss B, Widemann BC, Zhu Y, Bakker AC, Lloyd AC.

Am J Med Genet A. 2014 Dec;164A(12):2969-78. doi: 10.1002/ajmg.a.36754. Epub 2014 Sep 24. No abstract available.

PMID:
25255738
6.

Gene therapy for the nervous system: challenges and new strategies.

Maguire CA, Ramirez SH, Merkel SF, Sena-Esteves M, Breakefield XO.

Neurotherapeutics. 2014 Oct;11(4):817-39. doi: 10.1007/s13311-014-0299-5.

PMID:
25159276
7.

Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A.

Hettich J, Ryan SD, de Souza ON, Saraiva Macedo Timmers LF, Tsai S, Atai NA, da Hora CC, Zhang X, Kothary R, Snapp E, Ericsson M, Grundmann K, Breakefield XO, Nery FC.

Hum Mutat. 2014 Sep;35(9):1101-13. doi: 10.1002/humu.22602. Epub 2014 Jul 17.

PMID:
24930953
8.

Microfluidic platform to evaluate migration of cells from patients with DYT1 dystonia.

Nery FC, da Hora CC, Atai NA, Kim EY, Hettich J, Mempel TR, Breakefield XO, Irimia D.

J Neurosci Methods. 2014 Jul 30;232:181-8. doi: 10.1016/j.jneumeth.2014.05.027. Epub 2014 May 29.

PMID:
24880044
9.

Extracellular RNA mediates and marks cancer progression.

Redzic JS, Balaj L, van der Vos KE, Breakefield XO.

Semin Cancer Biol. 2014 Oct;28:14-23. doi: 10.1016/j.semcancer.2014.04.010. Epub 2014 Apr 28.

PMID:
24783980
10.

Extracellular vesicles: emerging targets for cancer therapy.

Vader P, Breakefield XO, Wood MJ.

Trends Mol Med. 2014 Jul;20(7):385-93. doi: 10.1016/j.molmed.2014.03.002. Epub 2014 Apr 3. Review.

PMID:
24703619
11.

Dynamic biodistribution of extracellular vesicles in vivo using a multimodal imaging reporter.

Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire CA, Chen JW, Tannous BA, Breakefield XO.

ACS Nano. 2014 Jan 28;8(1):483-94. doi: 10.1021/nn404945r. Epub 2014 Jan 9.

12.

MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.

Akers JC, Ramakrishnan V, Kim R, Skog J, Nakano I, Pingle S, Kalinina J, Hua W, Kesari S, Mao Y, Breakefield XO, Hochberg FH, Van Meir EG, Carter BS, Chen CC.

PLoS One. 2013 Oct 21;8(10):e78115. doi: 10.1371/journal.pone.0078115. eCollection 2013.

13.

Noninvasive in vivo monitoring of extracellular vesicles.

Lai CP, Tannous BA, Breakefield XO.

Methods Mol Biol. 2014;1098:249-58. doi: 10.1007/978-1-62703-718-1_19.

PMID:
24166382
14.

Dopa-responsive dystonia: functional analysis of single nucleotide substitutions within the 5' untranslated GCH1 region.

Armata IA, Balaj L, Kuster JK, Zhang X, Tsai S, Armatas AA, Multhaupt-Buell TJ, Soberman R, Breakefield XO, Ichinose H, Sharma N.

PLoS One. 2013 Oct 4;8(10):e76975. doi: 10.1371/journal.pone.0076975. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/4ace7171-c9d7-490b-a7d6-b49be4094281.

15.

Heparin blocks transfer of extracellular vesicles between donor and recipient cells.

Atai NA, Balaj L, van Veen H, Breakefield XO, Jarzyna PA, Van Noorden CJ, Skog J, Maguire CA.

J Neurooncol. 2013 Dec;115(3):343-51. doi: 10.1007/s11060-013-1235-y. Epub 2013 Sep 4.

16.

BEAMing and Droplet Digital PCR Analysis of Mutant IDH1 mRNA in Glioma Patient Serum and Cerebrospinal Fluid Extracellular Vesicles.

Chen WW, Balaj L, Liau LM, Samuels ML, Kotsopoulos SK, Maguire CA, Loguidice L, Soto H, Garrett M, Zhu LD, Sivaraman S, Chen C, Wong ET, Carter BS, Hochberg FH, Breakefield XO, Skog J.

Mol Ther Nucleic Acids. 2013 Jul 23;2:e109. doi: 10.1038/mtna.2013.28.

17.

Stochastic model of Tsc1 lesions in mouse brain.

Prabhakar S, Goto J, Zhang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO.

PLoS One. 2013 May 16;8(5):e64224. doi: 10.1371/journal.pone.0064224. Print 2013. Erratum in: PLoS One. 2013;8(11). doi:10.1371/annotation/6a5b0a50-27e4-49bc-b82a-9267dd63af53. Zuang, Xuan [corrected to Zhang, Xuan].

18.

Extracellular vesicles: biology and emerging therapeutic opportunities.

EL Andaloussi S, Mäger I, Breakefield XO, Wood MJ.

Nat Rev Drug Discov. 2013 May;12(5):347-57. doi: 10.1038/nrd3978. Epub 2013 Apr 15. Review.

PMID:
23584393
19.

Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases.

Tremblay JP, Xiao X, Aartsma-Rus A, Barbas C, Blau HM, Bogdanove AJ, Boycott K, Braun S, Breakefield XO, Bueren JA, Buschmann M, Byrne BJ, Calos M, Cathomen T, Chamberlain J, Chuah M, Cornetta K, Davies KE, Dickson JG, Duchateau P, Flotte TR, Gaudet D, Gersbach CA, Gilbert R, Glorioso J, Herzog RW, High KA, Huang W, Huard J, Joung JK, Liu D, Liu D, Lochmüller H, Lustig L, Martens J, Massie B, Mavilio F, Mendell JR, Nathwani A, Ponder K, Porteus M, Puymirat J, Samulski J, Takeda S, Thrasher A, VandenDriessche T, Wei Y, Wilson JM, Wilton SD, Wolfe JH, Gao G.

Mol Ther. 2013 Feb;21(2):266-8. doi: 10.1038/mt.2013.4. No abstract available.

20.

miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles.

Bolukbasi MF, Mizrak A, Ozdener GB, Madlener S, Ströbel T, Erkan EP, Fan JB, Breakefield XO, Saydam O.

Mol Ther Nucleic Acids. 2012 Feb 7;1:e10. doi: 10.1038/mtna.2011.2.

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