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Results: 12

1.

Synthesis and biological evaluation of a selective N- and p/q-type calcium channel agonist.

Liang M, Tarr TB, Bravo-Altamirano K, Valdomir G, Rensch G, Swanson L, DeStefino NR, Mazzarisi CM, Olszewski RA, Wilson GM, Meriney SD, Wipf P.

ACS Med Chem Lett. 2012 Oct 1;3(12):985-90. doi: 10.1021/ml3002083. eCollection 2012 Dec 13.

PMID:
24936234
[PubMed]
Free PMC Article
2.

In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human cancer xenografts.

Guo J, Clausen DM, Beumer JH, Parise RA, Egorin MJ, Bravo-Altamirano K, Wipf P, Sharlow ER, Wang QJ, Eiseman JL.

Cancer Chemother Pharmacol. 2013 Feb;71(2):331-44. doi: 10.1007/s00280-012-2010-z. Epub 2012 Oct 30.

PMID:
23108699
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Design, Synthesis, and Biological Evaluation of PKD Inhibitors.

George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P.

Pharmaceutics. 2011;3(2):186-228. doi: 10.3390/pharmaceutics3020186.

PMID:
22267986
[PubMed]
Free PMC Article
4.

Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D.

Bravo-Altamirano K, George KM, Frantz MC, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P.

ACS Med Chem Lett. 2011 Feb 14;2(2):154-159.

PMID:
21617763
[PubMed]
Free PMC Article
5.

Strategies for the asymmetric synthesis of H-phosphinate esters.

Bravo-Altamirano K, Coudray L, Deal EL, Montchamp JL.

Org Biomol Chem. 2010 Dec 21;8(24):5541-51. doi: 10.1039/c0ob00415d. Epub 2010 Oct 26.

PMID:
20978651
[PubMed - indexed for MEDLINE]
6.

Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility.

Lavalle CR, Bravo-Altamirano K, Giridhar KV, Chen J, Sharlow E, Lazo JS, Wipf P, Wang QJ.

BMC Chem Biol. 2010 May 5;10:5. doi: 10.1186/1472-6769-10-5.

PMID:
20444281
[PubMed]
Free PMC Article
7.

Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone.

Sharlow ER, Giridhar KV, LaValle CR, Chen J, Leimgruber S, Barrett R, Bravo-Altamirano K, Wipf P, Lazo JS, Wang QJ.

J Biol Chem. 2008 Nov 28;283(48):33516-26. doi: 10.1074/jbc.M805358200. Epub 2008 Sep 30.

PMID:
18829454
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Allylic phosphinates via palladium-catalyzed allylation of H-phosphinic acids with allylic alcohols.

Coudray L, Bravo-Altamirano K, Montchamp JL.

Org Lett. 2008 Mar 20;10(6):1123-6. doi: 10.1021/ol8000415. Epub 2008 Feb 21.

PMID:
18288851
[PubMed - indexed for MEDLINE]
9.

Palladium-catalyzed reactions of hypophosphorous compounds with allenes, dienes, and allylic electrophiles: methodology for the synthesis of allylic h-phosphinates.

Bravo-Altamirano K, Abrunhosa-Thomas I, Montchamp JL.

J Org Chem. 2008 Mar 21;73(6):2292-301. doi: 10.1021/jo702542a. Epub 2008 Feb 15.

PMID:
18275217
[PubMed - indexed for MEDLINE]
10.

A novel approach to phosphonic acids from hypophosphorous acid.

Bravo-Altamirano K, Montchamp JL.

Tetrahedron Lett. 2007 Aug 13;48(33):5755-5759.

PMID:
17940584
[PubMed]
Free PMC Article
11.

Palladium-catalyzed dehydrative allylation of hypophosphorous acid with allylic alcohols.

Bravo-Altamirano K, Montchamp JL.

Org Lett. 2006 Aug 31;8(18):4169-71.

PMID:
16928101
[PubMed]
12.

NiCl2-catalyzed hydrophosphinylation.

Ribière P, Bravo-Altamirano K, Antczak MI, Hawkins JD, Montchamp JL.

J Org Chem. 2005 May 13;70(10):4064-72.

PMID:
15876098
[PubMed]

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