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Results: 1 to 20 of 130

1.

The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors.

Mock K, Preca BT, Brummer T, Brabletz S, Stemmler MP, Brabletz T.

Oncotarget. 2015 May 5. [Epub ahead of print]

2.

Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression.

Shvab A, Haase G, Ben-Shmuel A, Gavert N, Brabletz T, Dedhar S, Ben-Ze'ev A.

Oncogene. 2015 Apr 27. doi: 10.1038/onc.2015.127. [Epub ahead of print]

PMID:
25915847
3.

ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat.

Meidhof S, Brabletz S, Lehmann W, Preca BT, Mock K, Ruh M, Schüler J, Berthold M, Weber A, Burk U, Lübbert M, Puhr M, Culig Z, Wellner U, Keck T, Bronsert P, Küsters S, Hopt UT, Stemmler MP, Brabletz T.

EMBO Mol Med. 2015 Apr 14. pii: e201404396. doi: 10.15252/emmm.201404396. [Epub ahead of print]

4.

Detailed analysis of epithelial-mesenchymal transition and tumor budding identifies predictors of long-term survival in pancreatic ductal adenocarcinoma.

Kohler I, Bronsert P, Timme S, Werner M, Brabletz T, Hopt UT, Schilling O, Bausch D, Keck T, Wellner UF.

J Gastroenterol Hepatol. 2015 Mar;30 Suppl 1:78-84. doi: 10.1111/jgh.12752.

PMID:
25827809
5.

Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition.

Alotaibi H, Basilicata MF, Shehwana H, Kosowan T, Schreck I, Braeutigam C, Konu O, Brabletz T, Stemmler MP.

Biochim Biophys Acta. 2015 Jun;1849(6):731-42. doi: 10.1016/j.bbagrm.2015.01.005. Epub 2015 Jan 31.

PMID:
25652130
6.

Cancer cell invasion and EMT marker expression: a three-dimensional study of the human cancer-host interface.

Bronsert P, Enderle-Ammour K, Bader M, Timme S, Kuehs M, Csanadi A, Kayser G, Kohler I, Bausch D, Hoeppner J, Hopt UT, Keck T, Stickeler E, Passlick B, Schilling O, Reiss CP, Vashist Y, Brabletz T, Berger J, Lotz J, Olesch J, Werner M, Wellner UF.

J Pathol. 2014 Nov;234(3):410-22. doi: 10.1002/path.4416.

PMID:
25081610
7.

Tumor cell heterogeneity in Small Cell Lung Cancer (SCLC): phenotypical and functional differences associated with Epithelial-Mesenchymal Transition (EMT) and DNA methylation changes.

Krohn A, Ahrens T, Yalcin A, Plönes T, Wehrle J, Taromi S, Wollner S, Follo M, Brabletz T, Mani SA, Claus R, Hackanson B, Burger M.

PLoS One. 2014 Jun 24;9(6):e100249. doi: 10.1371/journal.pone.0100249. eCollection 2014.

8.

Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer.

Bronsert P, Kohler I, Timme S, Kiefer S, Werner M, Schilling O, Vashist Y, Makowiec F, Brabletz T, Hopt UT, Bausch D, Kulemann B, Keck T, Wellner UF.

Surgery. 2014 Jul;156(1):97-108. doi: 10.1016/j.surg.2014.02.018. Epub 2014 Feb 28.

PMID:
24929761
9.

Oncogenic roles of EMT-inducing transcription factors.

Puisieux A, Brabletz T, Caramel J.

Nat Cell Biol. 2014 Jun;16(6):488-94. doi: 10.1038/ncb2976. Review.

PMID:
24875735
10.

Stress-induced cleavage of Myc promotes cancer cell survival.

Conacci-Sorrell M, Ngouenet C, Anderson S, Brabletz T, Eisenman RN.

Genes Dev. 2014 Apr 1;28(7):689-707. doi: 10.1101/gad.231894.113.

11.

Epithelial-mesenchymal transition induces endoplasmic-reticulum-stress response in human colorectal tumor cells.

Zeindl-Eberhart E, Brandl L, Liebmann S, Ormanns S, Scheel SK, Brabletz T, Kirchner T, Jung A.

PLoS One. 2014 Jan 31;9(1):e87386. doi: 10.1371/journal.pone.0087386. eCollection 2014.

12.

A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.

Li XL, Hara T, Choi Y, Subramanian M, Francis P, Bilke S, Walker RL, Pineda M, Zhu Y, Yang Y, Luo J, Wakefield LM, Brabletz T, Park BH, Sharma S, Chowdhury D, Meltzer PS, Lal A.

Mol Cell Biol. 2014 Feb;34(3):533-50. doi: 10.1128/MCB.01043-13. Epub 2013 Nov 25.

13.

Adhesion, but not a specific cadherin code, is indispensable for ES cell and induced pluripotency.

Bedzhov I, Alotaibi H, Basilicata MF, Ahlborn K, Liszewska E, Brabletz T, Stemmler MP.

Stem Cell Res. 2013 Nov;11(3):1250-63. doi: 10.1016/j.scr.2013.08.009. Epub 2013 Aug 26.

PMID:
24036274
14.

Roadblocks to translational advances on metastasis research.

Brabletz T, Lyden D, Steeg PS, Werb Z.

Nat Med. 2013 Sep;19(9):1104-9. doi: 10.1038/nm.3327.

15.

The ZEB1 pathway links glioblastoma initiation, invasion and chemoresistance.

Siebzehnrubl FA, Silver DJ, Tugertimur B, Deleyrolle LP, Siebzehnrubl D, Sarkisian MR, Devers KG, Yachnis AT, Kupper MD, Neal D, Nabilsi NH, Kladde MP, Suslov O, Brabletz S, Brabletz T, Reynolds BA, Steindler DA.

EMBO Mol Med. 2013 Aug;5(8):1196-212. doi: 10.1002/emmm.201302827. Epub 2013 Jul 1.

16.

Zeb1 regulates E-cadherin and Epcam (epithelial cell adhesion molecule) expression to control cell behavior in early zebrafish development.

Vannier C, Mock K, Brabletz T, Driever W.

J Biol Chem. 2013 Jun 28;288(26):18643-59. doi: 10.1074/jbc.M113.467787. Epub 2013 May 10.

17.

EMT and MET in metastasis: where are the cancer stem cells?

Brabletz T.

Cancer Cell. 2012 Dec 11;22(6):699-701. doi: 10.1016/j.ccr.2012.11.009.

18.

A transcription factor-based mechanism for mouse heterochromatin formation.

Bulut-Karslioglu A, Perrera V, Scaranaro M, de la Rosa-Velazquez IA, van de Nobelen S, Shukeir N, Popow J, Gerle B, Opravil S, Pagani M, Meidhof S, Brabletz T, Manke T, Lachner M, Jenuwein T.

Nat Struct Mol Biol. 2012 Oct;19(10):1023-30. doi: 10.1038/nsmb.2382. Epub 2012 Sep 16. Erratum in: Nat Struct Mol Biol. 2013 Feb;20(2):244.

PMID:
22983563
19.

Human telomerase reverse transcriptase (hTERT) is a target gene of β-catenin in human colorectal tumors.

Jaitner S, Reiche JA, Schäffauer AJ, Hiendlmeyer E, Herbst H, Brabletz T, Kirchner T, Jung A.

Cell Cycle. 2012 Sep 1;11(17):3331-8. doi: 10.4161/cc.21790. Epub 2012 Aug 16.

20.

Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-κB signaling that promotes colon cancer progression.

Ben-Shmuel A, Shvab A, Gavert N, Brabletz T, Ben-Ze'ev A.

Oncogene. 2013 Jul 4;32(27):3220-30. doi: 10.1038/onc.2012.340. Epub 2012 Aug 6.

PMID:
22869145
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