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Results: 1 to 20 of 135

1.

A crucial piece in the puzzle of the artemisinin resistance mechanism in Plasmodium falciparum.

Bozdech Z, Ferreira PE, Mok S.

Trends Parasitol. 2015 Jul 10. pii: S1471-4922(15)00137-3. doi: 10.1016/j.pt.2015.06.004. [Epub ahead of print]

PMID:
26169358
2.

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression.

Josling GA, Petter M, Oehring SC, Gupta AP, Dietz O, Wilson DW, Schubert T, Längst G, Gilson PR, Crabb BS, Moes S, Jenoe P, Lim SW, Brown GV, Bozdech Z, Voss TS, Duffy MF.

Cell Host Microbe. 2015 Jun 10;17(6):741-51. doi: 10.1016/j.chom.2015.05.009.

PMID:
26067602
3.

Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance.

Dogovski C, Xie SC, Burgio G, Bridgford J, Mok S, McCaw JM, Chotivanich K, Kenny S, Gnädig N, Straimer J, Bozdech Z, Fidock DA, Simpson JA, Dondorp AM, Foote S, Klonis N, Tilley L.

PLoS Biol. 2015 Apr 22;13(4):e1002132. doi: 10.1371/journal.pbio.1002132. eCollection 2015 Apr.

4.

Plasmodium knowlesi gene expression differs in ex vivo compared to in vitro blood-stage cultures.

Lapp SA, Mok S, Zhu L, Wu H, Preiser PR, Bozdech Z, Galinski MR.

Malar J. 2015 Mar 13;14:110. doi: 10.1186/s12936-015-0612-8.

5.

Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance.

Mok S, Ashley EA, Ferreira PE, Zhu L, Lin Z, Yeo T, Chotivanich K, Imwong M, Pukrittayakamee S, Dhorda M, Nguon C, Lim P, Amaratunga C, Suon S, Hien TT, Htut Y, Faiz MA, Onyamboko MA, Mayxay M, Newton PN, Tripura R, Woodrow CJ, Miotto O, Kwiatkowski DP, Nosten F, Day NP, Preiser PR, White NJ, Dondorp AM, Fairhurst RM, Bozdech Z.

Science. 2015 Jan 23;347(6220):431-5. doi: 10.1126/science.1260403. Epub 2014 Dec 11.

PMID:
25502316
6.

Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle.

Rai R, Zhu L, Chen H, Gupta AP, Sze SK, Zheng J, Ruedl C, Bozdech Z, Featherstone M.

BMC Genomics. 2014 Nov 6;15:959. doi: 10.1186/1471-2164-15-959.

7.

Heterochromatin protein 1 secures survival and transmission of malaria parasites.

Brancucci NM, Bertschi NL, Zhu L, Niederwieser I, Chin WH, Wampfler R, Freymond C, Rottmann M, Felger I, Bozdech Z, Voss TS.

Cell Host Microbe. 2014 Aug 13;16(2):165-76. doi: 10.1016/j.chom.2014.07.004.

PMID:
25121746
8.

Spread of artemisinin resistance in Plasmodium falciparum malaria.

Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Mao S, Sam B, Sopha C, Chuor CM, Nguon C, Sovannaroth S, Pukrittayakamee S, Jittamala P, Chotivanich K, Chutasmit K, Suchatsoonthorn C, Runcharoen R, Hien TT, Thuy-Nhien NT, Thanh NV, Phu NH, Htut Y, Han KT, Aye KH, Mokuolu OA, Olaosebikan RR, Folaranmi OO, Mayxay M, Khanthavong M, Hongvanthong B, Newton PN, Onyamboko MA, Fanello CI, Tshefu AK, Mishra N, Valecha N, Phyo AP, Nosten F, Yi P, Tripura R, Borrmann S, Bashraheil M, Peshu J, Faiz MA, Ghose A, Hossain MA, Samad R, Rahman MR, Hasan MM, Islam A, Miotto O, Amato R, MacInnis B, Stalker J, Kwiatkowski DP, Bozdech Z, Jeeyapant A, Cheah PY, Sakulthaew T, Chalk J, Intharabut B, Silamut K, Lee SJ, Vihokhern B, Kunasol C, Imwong M, Tarning J, Taylor WJ, Yeung S, Woodrow CJ, Flegg JA, Das D, Smith J, Venkatesan M, Plowe CV, Stepniewska K, Guerin PJ, Dondorp AM, Day NP, White NJ; Tracking Resistance to Artemisinin Collaboration (TRAC).

N Engl J Med. 2014 Jul 31;371(5):411-23. doi: 10.1056/NEJMoa1314981. Erratum in: N Engl J Med. 2014 Aug 21;371(8):786.

9.

Epigenetic memory takes center stage in the survival strategy of malaria parasites.

Voss TS, Bozdech Z, Bártfai R.

Curr Opin Microbiol. 2014 Aug;20:88-95. doi: 10.1016/j.mib.2014.05.007. Epub 2014 Jun 17. Review.

PMID:
24945736
10.

Role of calcium signaling in the transcriptional regulation of the apicoplast genome of Plasmodium falciparum.

Cheemadan S, Ramadoss R, Bozdech Z.

Biomed Res Int. 2014;2014:869401. doi: 10.1155/2014/869401. Epub 2014 Apr 27.

11.

Structural polymorphism in the promoter of pfmrp2 confers Plasmodium falciparum tolerance to quinoline drugs.

Mok S, Liong KY, Lim EH, Huang X, Zhu L, Preiser PR, Bozdech Z.

Mol Microbiol. 2014 Mar;91(5):918-34. doi: 10.1111/mmi.12505. Epub 2014 Jan 23.

12.

A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria.

Ch'ng JH, Mok S, Bozdech Z, Lear MJ, Boudhar A, Russell B, Nosten F, Tan KS.

Sci Rep. 2013;3:1734. doi: 10.1038/srep01734.

13.

Dynamic epigenetic regulation of gene expression during the life cycle of malaria parasite Plasmodium falciparum.

Gupta AP, Chin WH, Zhu L, Mok S, Luah YH, Lim EH, Bozdech Z.

PLoS Pathog. 2013 Feb;9(2):e1003170. doi: 10.1371/journal.ppat.1003170. Epub 2013 Feb 28.

14.

H2A.Z and H2B.Z double-variant nucleosomes define intergenic regions and dynamically occupy var gene promoters in the malaria parasite Plasmodium falciparum.

Petter M, Selvarajah SA, Lee CC, Chin WH, Gupta AP, Bozdech Z, Brown GV, Duffy MF.

Mol Microbiol. 2013 Mar;87(6):1167-82. doi: 10.1111/mmi.12154. Epub 2013 Feb 4.

PMID:
23373537
15.

DNA microarray-based genome-wide analyses of Plasmodium parasites.

Bozdech Z, Mok S, Gupta AP.

Methods Mol Biol. 2013;923:189-211.

PMID:
22990779
16.

Identification of a new chemical class of antimalarials.

Brunner R, Aissaoui H, Boss C, Bozdech Z, Brun R, Corminboeuf O, Delahaye S, Fischli C, Heidmann B, Kaiser M, Kamber J, Meyer S, Papastogiannidis P, Siegrist R, Voss T, Welford R, Wittlin S, Binkert C.

J Infect Dis. 2012 Sep 1;206(5):735-43. doi: 10.1093/infdis/jis418. Epub 2012 Jun 25.

17.

A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells.

Claessens A, Adams Y, Ghumra A, Lindergard G, Buchan CC, Andisi C, Bull PC, Mok S, Gupta AP, Wang CW, Turner L, Arman M, Raza A, Bozdech Z, Rowe JA.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):E1772-81. doi: 10.1073/pnas.1120461109. Epub 2012 May 22.

18.

Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling.

Witmer K, Schmid CD, Brancucci NM, Luah YH, Preiser PR, Bozdech Z, Voss TS.

Mol Microbiol. 2012 Apr;84(2):243-59. doi: 10.1111/j.1365-2958.2012.08019.x. Epub 2012 Mar 22.

19.

Transcriptional variation in the malaria parasite Plasmodium falciparum.

Rovira-Graells N, Gupta AP, Planet E, Crowley VM, Mok S, Ribas de Pouplana L, Preiser PR, Bozdech Z, Cortés A.

Genome Res. 2012 May;22(5):925-38. doi: 10.1101/gr.129692.111. Epub 2012 Mar 13.

20.

Comparative gene expression profiling of P. falciparum malaria parasites exposed to three different histone deacetylase inhibitors.

Andrews KT, Gupta AP, Tran TN, Fairlie DP, Gobert GN, Bozdech Z.

PLoS One. 2012;7(2):e31847. doi: 10.1371/journal.pone.0031847. Epub 2012 Feb 27.

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