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Items: 1 to 20 of 1617

1.

Safety, bioavailability, and pharmacokinetics of VGX-1027-A novel oral anti-inflammatory drug in healthy human subjects.

Lee JC, Menacherry S, Diehl MC, Giffear MD, White CJ, Juba R, Bagarazzi ML, Muthumani K, Boyer J, Agarwal V, Nicoletti F, Bart S, Kim JJ, Weiner DB, Sardesai NY.

Clin Pharmacol Drug Dev. 2016 Mar;5(2):91-101. doi: 10.1002/cpdd.193. Epub 2015 Jun 8.

PMID:
27138022
2.

Effect of Single Nucleotide Polymorphisms in the Xenobiotic-sensing Receptors NR1I2 and NR1I3 on the Pharmacokinetics and Toxicity of Irinotecan in Colorectal Cancer Patients.

Mbatchi LC, Robert J, Ychou M, Boyer JC, Del Rio M, Gassiot M, Thomas F, Tubiana N, Evrard A.

Clin Pharmacokinet. 2016 Apr 26. [Epub ahead of print]

PMID:
27116457
3.

Why small fluxes matter: the case and approaches for improving measurements of photosynthesis and (photo)respiration.

Hanson DT, Stutz SS, Boyer JS.

J Exp Bot. 2016 Apr 19. pii: erw139. [Epub ahead of print] Review.

PMID:
27099373
4.

Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease.

Karuppuchamy T, Behrens EH, González-Cabrera P, Sarkisyan G, Gima L, Boyer JD, Bamias G, Jedlicka P, Veny M, Clark D, Peach R, Scott F, Rosen H, Rivera-Nieves J.

Mucosal Immunol. 2016 Apr 6. doi: 10.1038/mi.2016.35. [Epub ahead of print]

PMID:
27049060
5.

Presence of commensal house dust mite allergen in human gastrointestinal tract: a potential contributor to intestinal barrier dysfunction.

Tulic MK, Vivinus-Nébot M, Rekima A, Rabelo Medeiros S, Bonnart C, Shi H, Walker A, Dainese R, Boyer J, Vergnolle N, Piche T, Verhasselt V.

Gut. 2016 May;65(5):757-66. doi: 10.1136/gutjnl-2015-310523. Epub 2015 Dec 8.

PMID:
26646935
6.

A pilot study of pNGVL4a-CRT/E7(detox) for the treatment of patients with HPV16+ cervical intraepithelial neoplasia 2/3 (CIN2/3).

Alvarez RD, Huh WK, Bae S, Lamb LS Jr, Conner MG, Boyer J, Wang C, Hung CF, Sauter E, Paradis M, Adams EA, Hester S, Jackson BE, Wu TC, Trimble CL.

Gynecol Oncol. 2016 Feb;140(2):245-52. doi: 10.1016/j.ygyno.2015.11.026. Epub 2015 Nov 23.

PMID:
26616223
7.

APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.

Ye B, Hou N, Xiao L, Xu Y, Boyer J, Xu H, Li F.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):287-96. doi: 10.1016/j.yjmcc.2015.10.018. Epub 2015 Oct 19.

PMID:
26493106
8.

Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.

Trimble CL, Morrow MP, Kraynyak KA, Shen X, Dallas M, Yan J, Edwards L, Parker RL, Denny L, Giffear M, Brown AS, Marcozzi-Pierce K, Shah D, Slager AM, Sylvester AJ, Khan A, Broderick KE, Juba RJ, Herring TA, Boyer J, Lee J, Sardesai NY, Weiner DB, Bagarazzi ML.

Lancet. 2015 Nov 21;386(10008):2078-88. doi: 10.1016/S0140-6736(15)00239-1. Epub 2015 Sep 17.

PMID:
26386540
9.

Health Behaviors and Overweight in Nursing Home Employees: Contribution of Workplace Stressors and Implications for Worksite Health Promotion.

Miranda H, Gore RJ, Boyer J, Nobrega S, Punnett L.

ScientificWorldJournal. 2015;2015:915359. doi: 10.1155/2015/915359. Epub 2015 Aug 25.

10.

Polymorphisms in SLCO1B3 and NR1I2 as genetic determinants of hematotoxicity of carboplatin and paclitaxel combination.

Mbatchi LC, Schmitt A, Thomas F, Cazaubon Y, Robert J, Lumbroso S, Brouillet JP, Pourquier P, Chatelut E, Boyer JC, Evrard A.

Pharmacogenomics. 2015;16(13):1439-50. doi: 10.2217/pgs.15.84. Epub 2015 Aug 12.

PMID:
26267044
11.

Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c-c motif) Ligand 20.

Lahoti TS, Boyer JA, Kusnadi A, Muku GE, Murray IA, Perdew GH.

Toxicol Sci. 2015 Nov;148(1):229-40. doi: 10.1093/toxsci/kfv178. Epub 2015 Aug 10.

PMID:
26259605
12.

Impact of cuticle on calculations of the CO2 concentration inside leaves.

Boyer JS.

Planta. 2015 Dec;242(6):1405-12. doi: 10.1007/s00425-015-2378-1. Epub 2015 Aug 8.

PMID:
26253179
13.

Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis.

Chai J, Cai SY, Liu X, Lian W, Chen S, Zhang L, Feng X, Cheng Y, He X, He Y, Chen L, Wang R, Wang H, Boyer JL, Chen W.

J Hepatol. 2015 Dec;63(6):1440-8. doi: 10.1016/j.jhep.2015.07.016. Epub 2015 Jul 23.

PMID:
26212029
14.

Arthralgia among women taking aromatase inhibitors: is there a shared inflammatory mechanism with co-morbid fatigue and insomnia?

Bauml J, Chen L, Chen J, Boyer J, Kalos M, Li SQ, DeMichele A, Mao JJ.

Breast Cancer Res. 2015 Jun 28;17:89. doi: 10.1186/s13058-015-0599-7.

15.

Na(+) /H(+) exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury.

Li M, Mennone A, Soroka CJ, Hagey LR, Ouyang X, Weinman EJ, Boyer JL.

Hepatology. 2015 Oct;62(4):1227-36. doi: 10.1002/hep.27956. Epub 2015 Aug 22.

PMID:
26108984
16.

The Arabidopsis root stele transporter NPF2.3 contributes to nitrate translocation to shoots under salt stress.

Taochy C, Gaillard I, Ipotesi E, Oomen R, Leonhardt N, Zimmermann S, Peltier JB, Szponarski W, Simonneau T, Sentenac H, Gibrat R, Boyer JC.

Plant J. 2015 Aug;83(3):466-79. doi: 10.1111/tpj.12901. Epub 2015 Jul 2.

PMID:
26058834
17.

A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress.

Lee JW, Park HS, Park SA, Ryu SH, Meng W, Jürgensmeier JM, Kurie JM, Hong WK, Boyer JL, Herbst RS, Koo JS.

PLoS One. 2015 Apr 21;10(4):e0122628. doi: 10.1371/journal.pone.0122628. eCollection 2015.

18.

Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector.

Burke BP, Levin BR, Zhang J, Sahakyan A, Boyer J, Carroll MV, Colón JC, Keech N, Rezek V, Bristol G, Eggers E, Cortado R, Boyd MP, Impey H, Shimizu S, Lowe EL, Ringpis GE, Kim SG, Vatakis DN, Breton LR, Bartlett JS, Chen IS, Kitchen SG, An DS, Symonds GP.

Mol Ther Nucleic Acids. 2015 Apr 14;4:e236. doi: 10.1038/mtna.2015.10.

PMID:
25872029
19.

UGT1A1 genotype and irinotecan therapy: general review and implementation in routine practice.

Etienne-Grimaldi MC, Boyer JC, Thomas F, Quaranta S, Picard N, Loriot MA, Narjoz C, Poncet D, Gagnieu MC, Ged C, Broly F, Le Morvan V, Bouquié R, Gaub MP, Philibert L, Ghiringhelli F, Le Guellec C; Collective work by Groupe de Pharmacologie Clinique Oncologique (GPCO-Unicancer); French Réseau National de Pharmacogénétique Hospitalière (RNPGx).

Fundam Clin Pharmacol. 2015 Jun;29(3):219-37. doi: 10.1111/fcp.12117. Epub 2015 May 4.

PMID:
25817555
20.

Turgor and the transport of CO2 and water across the cuticle (epidermis) of leaves.

Boyer JS.

J Exp Bot. 2015 May;66(9):2625-33. doi: 10.1093/jxb/erv065. Epub 2015 Mar 3.

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