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Results: 1 to 20 of 57

1.

Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease.

Friedman EA, Ogletree ML, Haddad EV, Boutaud O.

Thromb Res. 2015 May 28. pii: S0049-3848(15)30007-4. doi: 10.1016/j.thromres.2015.05.027. [Epub ahead of print] Review.

PMID:
26077962
2.

Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.

Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ 2nd, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT.

J Mol Cell Cardiol. 2015 Feb;79:295-302. doi: 10.1016/j.yjmcc.2014.11.013. Epub 2014 Nov 18.

PMID:
25463275
3.

Protein modification by adenine propenal.

Shuck SC, Wauchope OR, Rose KL, Kingsley PJ, Rouzer CA, Shell SM, Sugitani N, Chazin WJ, Zagol-Ikapitte I, Boutaud O, Oates JA, Galligan JJ, Beavers WN, Marnett LJ.

Chem Res Toxicol. 2014 Oct 20;27(10):1732-42. doi: 10.1021/tx500218g. Epub 2014 Sep 24.

PMID:
25211669
4.

Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling.

Woodling NS, Wang Q, Priyam PG, Larkin P, Shi J, Johansson JU, Zagol-Ikapitte I, Boutaud O, Andreasson KI.

J Neurosci. 2014 Apr 23;34(17):5882-94. doi: 10.1523/JNEUROSCI.0410-14.2014.

5.

Levuglandin forms adducts with histone h4 in a cyclooxygenase-2-dependent manner, altering its interaction with DNA.

Carrier EJ, Zagol-Ikapitte I, Amarnath V, Boutaud O, Oates JA.

Biochemistry. 2014 Apr 22;53(15):2436-41. doi: 10.1021/bi401673b. Epub 2014 Apr 11.

6.

Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues.

Shchepin RV, Liu W, Yin H, Zagol-Ikapitte I, Amin T, Jeong BS, Roberts LJ 2nd, Oates JA, Porter NA, Boutaud O.

ACS Med Chem Lett. 2013 Aug 8;4(8):710-714.

7.

12-lipoxygenase activity plays an important role in PAR4 and GPVI-mediated platelet reactivity.

Yeung J, Apopa PL, Vesci J, Stolla M, Rai G, Simeonov A, Jadhav A, Fernandez-Perez P, Maloney DJ, Boutaud O, Holman TR, Holinstat M.

Thromb Haemost. 2013 Sep;110(3):569-81. doi: 10.1160/TH13-01-0014. Epub 2013 Jun 20. Erratum in: Thromb Haemost. 2014 Aug;112(2):426.

8.

Acetaminophen inhibits cytochrome c redox cycling induced lipid peroxidation.

Yin H, Vergeade A, Shi Q, Zackert WE, Gruenberg KC, Bokiej M, Amin T, Ying W, Masterson TS, Zinkel SS, Oates JA, Boutaud O, Roberts LJ 2nd.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):224-8. doi: 10.1016/j.bbrc.2012.05.058. Epub 2012 May 23.

9.

Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome.

Smith JP, Haddad EV, Taylor MB, Oram D, Blakemore D, Chen Q, Boutaud O, Oates JA.

Hypertension. 2012 Mar;59(3):719-25. doi: 10.1161/HYPERTENSIONAHA.111.181404. Epub 2012 Feb 6.

10.

Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation.

Yeung J, Apopa PL, Vesci J, Kenyon V, Rai G, Jadhav A, Simeonov A, Holman TR, Maloney DJ, Boutaud O, Holinstat M.

Mol Pharmacol. 2012 Mar;81(3):420-30. doi: 10.1124/mol.111.075630. Epub 2011 Dec 9.

11.

On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry.

Chacon A, Zagol-Ikapitte I, Amarnath V, Reyzer ML, Oates JA, Caprioli RM, Boutaud O.

J Mass Spectrom. 2011 Aug;46(8):840-6. doi: 10.1002/jms.1958.

12.

Determination of 3-methoxysalicylamine levels in mouse plasma and tissue by liquid chromatography-tandem mass spectrometry: application to in vivo pharmacokinetics studies.

Zagol-Ikapitte I, Amarnath V, Jadhav S, Oates JA, Boutaud O.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 May 1;879(15-16):1098-104. doi: 10.1016/j.jchromb.2011.03.026. Epub 2011 Mar 21.

13.

Functional characterization of mutations in inherited human cPLA₂ deficiency.

Reed KA, Tucker DE, Aloulou A, Adler D, Ghomashchi F, Gelb MH, Leslie CC, Oates JA, Boutaud O.

Biochemistry. 2011 Mar 15;50(10):1731-8. doi: 10.1021/bi101877n. Epub 2011 Feb 9.

14.

Primate-specific evolution of noncoding element insertion into PLA2G4C and human preterm birth.

Plunkett J, Doniger S, Morgan T, Haataja R, Hallman M, Puttonen H, Menon R, Kuczynski E, Norwitz E, Snegovskikh V, Palotie A, Peltonen L, Fellman V, DeFranco EA, Chaudhari BP, Oates J, Boutaud O, McGregor TL, McElroy JJ, Teramo K, Borecki I, Fay JC, Muglia LJ.

BMC Med Genomics. 2010 Dec 24;3:62. doi: 10.1186/1755-8794-3-62.

15.

Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis.

Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, Hamm HE.

Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):435-42. doi: 10.1161/ATVBAHA.110.219527. Epub 2010 Dec 2.

16.

Mechanism-based therapeutic approaches to rhabdomyolysis-induced renal failure.

Boutaud O, Roberts LJ 2nd.

Free Radic Biol Med. 2011 Sep 1;51(5):1062-7. doi: 10.1016/j.freeradbiomed.2010.10.704. Epub 2010 Oct 27. Review.

17.

Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes.

Boutaud O, Oates JA.

Methods Mol Biol. 2010;644:67-90. doi: 10.1007/978-1-59745-364-6_7.

PMID:
20645166
18.

PGE2 decreases reactivity of human platelets by activating EP2 and EP4.

Smith JP, Haddad EV, Downey JD, Breyer RM, Boutaud O.

Thromb Res. 2010 Jul;126(1):e23-9. doi: 10.1016/j.thromres.2010.04.003. Epub 2010 May 8.

19.

Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS.

Zagol-Ikapitte IA, Matafonova E, Amarnath V, Bodine CL, Boutaud O, Tirona RG, Oates JA, Roberts LJ 2nd, Davies SS.

Pharmaceutics. 2010 Mar;2(1):18-29.

20.

Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure.

Boutaud O, Moore KP, Reeder BJ, Harry D, Howie AJ, Wang S, Carney CK, Masterson TS, Amin T, Wright DW, Wilson MT, Oates JA, Roberts LJ 2nd.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2699-704. doi: 10.1073/pnas.0910174107. Epub 2010 Feb 1.

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