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Results: 1 to 20 of 55

1.

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.

Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Barszczyk M, Chornenkyy Y, Bourgey M, Bourque G, Montpetit A, Cordero F, Castelo-Branco P, Mangerel J, Tabori U, Ho KC, Huang A, Taylor KR, Mackay A, Bendel AE, Nazarian J, Fangusaro JR, Karajannis MA, Zagzag D, Foreman NK, Donson A, Hegert JV, Smith A, Chan J, Lafay-Cousin L, Dunn S, Hukin J, Dunham C, Scheinemann K, Michaud J, Zelcer S, Ramsay D, Cain J, Brennan C, Souweidane MM, Jones C, Allis CD, Brudno M, Becher O, Hawkins C.

Nat Genet. 2014 May;46(5):451-6. doi: 10.1038/ng.2936. Epub 2014 Apr 6.

PMID:
24705254
[PubMed - indexed for MEDLINE]
2.

The retrovirus HERVH is a long noncoding RNA required for human embryonic stem cell identity.

Lu X, Sachs F, Ramsay L, Jacques PÉ, Göke J, Bourque G, Ng HH.

Nat Struct Mol Biol. 2014 Apr;21(4):423-5. doi: 10.1038/nsmb.2799. Epub 2014 Mar 30.

PMID:
24681886
[PubMed - indexed for MEDLINE]
3.

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.

Magnus N, Garnier D, Meehan B, McGraw S, Lee TH, Caron M, Bourque G, Milsom C, Jabado N, Trasler J, Pawlinski R, Mackman N, Rak J.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3544-9. doi: 10.1073/pnas.1314118111. Epub 2014 Feb 11.

PMID:
24520174
[PubMed - indexed for MEDLINE]
4.

SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells.

Lu X, Göke J, Sachs F, Jacques PÉ, Liang H, Feng B, Bourque G, Bubulya PA, Ng HH.

Nat Cell Biol. 2013 Oct;15(10):1141-52. doi: 10.1038/ncb2839. Epub 2013 Sep 8.

PMID:
24013217
[PubMed - indexed for MEDLINE]
5.

The majority of primate-specific regulatory sequences are derived from transposable elements.

Jacques PÉ, Jeyakani J, Bourque G.

PLoS Genet. 2013 May;9(5):e1003504. doi: 10.1371/journal.pgen.1003504. Epub 2013 May 9.

PMID:
23675311
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs.

Kapusta A, Kronenberg Z, Lynch VJ, Zhuo X, Ramsay L, Bourque G, Yandell M, Feschotte C.

PLoS Genet. 2013 Apr;9(4):e1003470. doi: 10.1371/journal.pgen.1003470. Epub 2013 Apr 25.

PMID:
23637635
[PubMed - in process]
Free PMC Article
7.

Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver.

Chaveroux C, Eichner LJ, Dufour CR, Shatnawi A, Khoutorsky A, Bourque G, Sonenberg N, Giguère V.

Cell Metab. 2013 Apr 2;17(4):586-98. doi: 10.1016/j.cmet.2013.03.003.

PMID:
23562079
[PubMed - indexed for MEDLINE]
Free Article
8.

Whole-genome reconstruction and mutational signatures in gastric cancer.

Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ, Yao F, Jacques PE, Teo AS, Cutcutache I, Zhang Z, Lee WH, Sia YY, Gao S, Ariyaratne PN, Ho A, Woo XY, Veeravali L, Ong CK, Deng N, Desai KV, Khor CC, Hibberd ML, Shahab A, Rao J, Wu M, Teh M, Zhu F, Chin SY, Pang B, So JB, Bourque G, Soong R, Sung WK, Tean Teh B, Rozen S, Ruan X, Yeoh KG, Tan PB, Ruan Y.

Genome Biol. 2012 Dec 13;13(12):R115.

PMID:
23237666
[PubMed - as supplied by publisher]
Free PMC Article
9.

PPARG binding landscapes in macrophages suggest a genome-wide contribution of PU.1 to divergent PPARG binding in human and mouse.

Pott S, Kamrani NK, Bourque G, Pettersson S, Liu ET.

PLoS One. 2012;7(10):e48102. doi: 10.1371/journal.pone.0048102. Epub 2012 Oct 31.

PMID:
23118933
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons.

Yao F, Ariyaratne PN, Hillmer AM, Lee WH, Li G, Teo AS, Woo XY, Zhang Z, Chen JP, Poh WT, Zawack KF, Chan CS, Leong ST, Neo SC, Choi PS, Gao S, Nagarajan N, Thoreau H, Shahab A, Ruan X, Cacheux-Rataboul V, Wei CL, Bourque G, Sung WK, Liu ET, Ruan Y.

PLoS One. 2012;7(9):e46152. doi: 10.1371/journal.pone.0046152. Epub 2012 Sep 28.

PMID:
23029419
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.

Khuong-Quang DA, Buczkowicz P, Rakopoulos P, Liu XY, Fontebasso AM, Bouffet E, Bartels U, Albrecht S, Schwartzentruber J, Letourneau L, Bourgey M, Bourque G, Montpetit A, Bourret G, Lepage P, Fleming A, Lichter P, Kool M, von Deimling A, Sturm D, Korshunov A, Faury D, Jones DT, Majewski J, Pfister SM, Jabado N, Hawkins C.

Acta Neuropathol. 2012 Sep;124(3):439-47. doi: 10.1007/s00401-012-0998-0. Epub 2012 Jun 3.

PMID:
22661320
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors.

Bard-Chapeau EA, Jeyakani J, Kok CH, Muller J, Chua BQ, Gunaratne J, Batagov A, Jenjaroenpun P, Kuznetsov VA, Wei CL, D'Andrea RJ, Bourque G, Jenkins NA, Copeland NG.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2168-73. doi: 10.1073/pnas.1119229109. Epub 2012 Jan 19.

PMID:
22308434
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

CpG deamination creates transcription factor-binding sites with high efficiency.

Zemojtel T, Kielbasa SM, Arndt PF, Behrens S, Bourque G, Vingron M.

Genome Biol Evol. 2011;3:1304-11. doi: 10.1093/gbe/evr107. Epub 2011 Oct 19.

PMID:
22016335
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes.

Chatterjee S, Bourque G, Lufkin T.

BMC Dev Biol. 2011 Oct 20;11:63. doi: 10.1186/1471-213X-11-63.

PMID:
22011226
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

CTCF-mediated functional chromatin interactome in pluripotent cells.

Handoko L, Xu H, Li G, Ngan CY, Chew E, Schnapp M, Lee CW, Ye C, Ping JL, Mulawadi F, Wong E, Sheng J, Zhang Y, Poh T, Chan CS, Kunarso G, Shahab A, Bourque G, Cacheux-Rataboul V, Sung WK, Ruan Y, Wei CL.

Nat Genet. 2011 Jun 19;43(7):630-8. doi: 10.1038/ng.857. Erratum in: Nat Genet. 2011 Aug;43(8):815.

PMID:
21685913
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Molecular conservation of estrogen-response associated with cell cycle regulation, hormonal carcinogenesis and cancer in zebrafish and human cancer cell lines.

Lam SH, Lee SG, Lin CY, Thomsen JS, Fu PY, Murthy KR, Li H, Govindarajan KR, Nick LC, Bourque G, Gong Z, Lufkin T, Liu ET, Mathavan S.

BMC Med Genomics. 2011 May 16;4:41. doi: 10.1186/1755-8794-4-41.

PMID:
21575170
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

In silico tandem affinity purification refines an Oct4 interaction list.

Cheong CY, Lon Ng PM, Ponnampalam R, Tsai HH, Bourque G, Lufkin T.

Stem Cell Res Ther. 2011 May 13;2(3):26. doi: 10.1186/scrt67.

PMID:
21569470
[PubMed - in process]
Free PMC Article
18.

Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition.

Aanes H, Winata CL, Lin CH, Chen JP, Srinivasan KG, Lee SG, Lim AY, Hajan HS, Collas P, Bourque G, Gong Z, Korzh V, Aleström P, Mathavan S.

Genome Res. 2011 Aug;21(8):1328-38. doi: 10.1101/gr.116012.110. Epub 2011 May 9.

PMID:
21555364
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes.

Hillmer AM, Yao F, Inaki K, Lee WH, Ariyaratne PN, Teo AS, Woo XY, Zhang Z, Zhao H, Ukil L, Chen JP, Zhu F, So JB, Salto-Tellez M, Poh WT, Zawack KF, Nagarajan N, Gao S, Li G, Kumar V, Lim HP, Sia YY, Chan CS, Leong ST, Neo SC, Choi PS, Thoreau H, Tan PB, Shahab A, Ruan X, Bergh J, Hall P, Cacheux-Rataboul V, Wei CL, Yeoh KG, Sung WK, Bourque G, Liu ET, Ruan Y.

Genome Res. 2011 May;21(5):665-75. doi: 10.1101/gr.113555.110. Epub 2011 Apr 5.

PMID:
21467267
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Transcriptional consequences of genomic structural aberrations in breast cancer.

Inaki K, Hillmer AM, Ukil L, Yao F, Woo XY, Vardy LA, Zawack KF, Lee CW, Ariyaratne PN, Chan YS, Desai KV, Bergh J, Hall P, Putti TC, Ong WL, Shahab A, Cacheux-Rataboul V, Karuturi RK, Sung WK, Ruan X, Bourque G, Ruan Y, Liu ET.

Genome Res. 2011 May;21(5):676-87. doi: 10.1101/gr.113225.110. Epub 2011 Apr 5.

PMID:
21467264
[PubMed - indexed for MEDLINE]
Free PMC Article

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