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Results: 1 to 20 of 55

1.

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria.

Srinivasan P, Ekanem E, Diouf A, Tonkin ML, Miura K, Boulanger MJ, Long CA, Narum DL, Miller LH.

Proc Natl Acad Sci U S A. 2014 Jun 23. pii: 201409928. [Epub ahead of print]

PMID:
24958881
[PubMed - as supplied by publisher]
Free Article
2.

Plasticity and redundancy among AMA-RON pairs ensure host cell entry of Toxoplasma parasites.

Lamarque MH, Roques M, Kong-Hap M, Tonkin ML, Rugarabamu G, Marq JB, Penarete-Vargas DM, Boulanger MJ, Soldati-Favre D, Lebrun M.

Nat Commun. 2014 Jun 17;5:4098. doi: 10.1038/ncomms5098.

PMID:
24934579
[PubMed - in process]
3.

The inner membrane complex sub-compartment proteins critical for replication of the apicomplexan parasite Toxoplasma gondii adopt a Pleckstrin homology fold.

Tonkin ML, Beck JR, Bradley PJ, Boulanger MJ.

J Biol Chem. 2014 Mar 27. [Epub ahead of print]

PMID:
24675080
[PubMed - as supplied by publisher]
Free Article
4.

Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7).

Simhadri C, Daze KD, Douglas SF, Quon TT, Dev A, Gignac MC, Peng F, Heller M, Boulanger MJ, Wulff JE, Hof F.

J Med Chem. 2014 Apr 10;57(7):2874-83. doi: 10.1021/jm401487x. Epub 2014 Mar 26.

PMID:
24625057
[PubMed - indexed for MEDLINE]
5.

The multifunctional role of the pallilysin-associated Treponema pallidum protein, Tp0750, in promoting fibrinolysis and extracellular matrix component degradation.

Houston S, Russell S, Hof R, Roberts AK, Cullen P, Irvine K, Smith DS, Borchers CH, Tonkin ML, Boulanger MJ, Cameron CE.

Mol Microbiol. 2014 Feb;91(3):618-34. doi: 10.1111/mmi.12482. Epub 2014 Jan 7.

PMID:
24303899
[PubMed - in process]
6.

Toxoplasma gondii sporozoites invade host cells using two novel paralogues of RON2 and AMA1.

Poukchanski A, Fritz HM, Tonkin ML, Treeck M, Boulanger MJ, Boothroyd JC.

PLoS One. 2013 Aug 5;8(8):e70637. doi: 10.1371/journal.pone.0070637. Print 2013.

PMID:
23940612
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design.

Von Kreudenstein TS, Escobar-Carbrera E, Lario PI, D'Angelo I, Brault K, Kelly J, Durocher Y, Baardsnes J, Woods RJ, Xie MH, Girod PA, Suits MD, Boulanger MJ, Poon DK, Ng GY, Dixit SB.

MAbs. 2013 Sep-Oct;5(5):646-54. doi: 10.4161/mabs.25632. Epub 2013 Jul 8.

PMID:
23924797
[PubMed - indexed for MEDLINE]
8.

Structural and biochemical characterization of Plasmodium falciparum 12 (Pf12) reveals a unique interdomain organization and the potential for an antiparallel arrangement with Pf41.

Tonkin ML, Arredondo SA, Loveless BC, Serpa JJ, Makepeace KA, Sundar N, Petrotchenko EV, Miller LH, Grigg ME, Boulanger MJ.

J Biol Chem. 2013 May 3;288(18):12805-17. doi: 10.1074/jbc.M113.455667. Epub 2013 Mar 19.

PMID:
23511632
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Purification, crystallization and X-ray diffraction analysis of Trypanosoma congolense insect-stage surface antigen (TcCISSA).

Tonkin ML, Workman SD, Eyford BA, Loveless BC, Fudge JL, Pearson TW, Boulanger MJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Dec 1;68(Pt 12):1503-6. doi: 10.1107/S1744309112042686. Epub 2012 Nov 14.

PMID:
23192033
[PubMed - indexed for MEDLINE]
10.

Babesia divergens and Neospora caninum apical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion.

Tonkin ML, Crawford J, Lebrun ML, Boulanger MJ.

Protein Sci. 2013 Jan;22(1):114-27. doi: 10.1002/pro.2193.

PMID:
23169033
[PubMed - in process]
Free PMC Article
11.

Integrated bioinformatic and targeted deletion analyses of the SRS gene superfamily identify SRS29C as a negative regulator of Toxoplasma virulence.

Wasmuth JD, Pszenny V, Haile S, Jansen EM, Gast AT, Sher A, Boyle JP, Boulanger MJ, Parkinson J, Grigg ME.

MBio. 2012 Nov 13;3(6). pii: e00321-12. doi: 10.1128/mBio.00321-12.

PMID:
23149485
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Investigating terephthalate biodegradation: structural characterization of a putative decarboxylating cis-dihydrodiol dehydrogenase.

Bains J, Wulff JE, Boulanger MJ.

J Mol Biol. 2012 Oct 26;423(3):284-93. doi: 10.1016/j.jmb.2012.07.022. Epub 2012 Aug 11.

PMID:
22889862
[PubMed - indexed for MEDLINE]
13.

Purification, crystallization and preliminary X-ray diffraction analysis of inner membrane complex (IMC) subcompartment protein 1 (ISP1) from Toxoplasma gondii.

Tonkin ML, Brown S, Beck JR, Bradley PJ, Boulanger MJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):832-4. doi: 10.1107/S174430911202297X. Epub 2012 Jun 28.

PMID:
22750877
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Structural characterization of S100A15 reveals a novel zinc coordination site among S100 proteins and altered surface chemistry with functional implications for receptor binding.

Murray JI, Tonkin ML, Whiting AL, Peng F, Farnell B, Cullen JT, Hof F, Boulanger MJ.

BMC Struct Biol. 2012 Jul 2;12:16. doi: 10.1186/1472-6807-12-16.

PMID:
22747601
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Structural and functional insights into the malaria parasite moving junction complex.

Vulliez-Le Normand B, Tonkin ML, Lamarque MH, Langer S, Hoos S, Roques M, Saul FA, Faber BW, Bentley GA, Boulanger MJ, Lebrun M.

PLoS Pathog. 2012;8(6):e1002755. doi: 10.1371/journal.ppat.1002755. Epub 2012 Jun 21.

PMID:
22737069
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.

Bromba CM, Mason JW, Brant MG, Chan T, Lunke MD, Petric M, Boulanger MJ, Wulff JE.

Bioorg Med Chem Lett. 2011 Dec 1;21(23):7137-41. doi: 10.1016/j.bmcl.2011.09.076. Epub 2011 Sep 24.

PMID:
22001088
[PubMed - indexed for MEDLINE]
17.

Host cell invasion by apicomplexan parasites: insights from the co-structure of AMA1 with a RON2 peptide.

Tonkin ML, Roques M, Lamarque MH, Pugnière M, Douguet D, Crawford J, Lebrun M, Boulanger MJ.

Science. 2011 Jul 22;333(6041):463-7. doi: 10.1126/science.1204988.

PMID:
21778402
[PubMed - indexed for MEDLINE]
Free Article
18.

Elucidating the reaction mechanism of the benzoate oxidation pathway encoded aldehyde dehydrogenase from Burkholderia xenovorans LB400.

Bains J, Leon R, Temke KG, Boulanger MJ.

Protein Sci. 2011 Jun;20(6):1048-59. doi: 10.1002/pro.639. Epub 2011 May 4.

PMID:
21495107
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Structural characterization and epitope mapping of the glutamic acid/alanine-rich protein from Trypanosoma congolense: defining assembly on the parasite cell surface.

Loveless BC, Mason JW, Sakurai T, Inoue N, Razavi M, Pearson TW, Boulanger MJ.

J Biol Chem. 2011 Jun 10;286(23):20658-65. doi: 10.1074/jbc.M111.218941. Epub 2011 Apr 6.

PMID:
21471223
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Defining a structural and kinetic rationale for paralogous copies of phenylacetate-CoA ligases from the cystic fibrosis pathogen Burkholderia cenocepacia J2315.

Law A, Boulanger MJ.

J Biol Chem. 2011 Apr 29;286(17):15577-85. doi: 10.1074/jbc.M111.219683. Epub 2011 Mar 8.

PMID:
21388965
[PubMed - indexed for MEDLINE]
Free PMC Article

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