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Results: 1 to 20 of 135

1.

Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis.

de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J, Niv Y, Herdman DS, Taniguchi K, Kim CW, Dong H, Eckmann L, Stanford SM, Bottini N, Corr M, Raz E.

J Clin Invest. 2014 Sep 2;124(9):3793-806. doi: 10.1172/JCI72340. Epub 2014 Aug 1.

PMID:
25083990
[PubMed - in process]
Free PMC Article
2.

"PEST control": regulation of molecular barcodes by tyrosine phosphatases.

Doody KM, Bottini N.

Cell Res. 2014 Sep;24(9):1027-8. doi: 10.1038/cr.2014.100. Epub 2014 Aug 1.

PMID:
25081059
[PubMed - in process]
3.

PTPN22: the archetypal non-HLA autoimmunity gene.

Stanford SM, Bottini N.

Nat Rev Rheumatol. 2014 Jul 8. doi: 10.1038/nrrheum.2014.109. [Epub ahead of print] Review.

PMID:
25003765
[PubMed - as supplied by publisher]
4.

The protein tyrosine phosphatase PTPN22 controls forkhead box protein 3 T regulatory cell induction but is dispensable for T helper type 1 cell polarization.

Fousteri G, Jofra T, Debernardis I, Stanford SM, Laurenzi A, Bottini N, Battaglia M.

Clin Exp Immunol. 2014 Oct;178(1):178-89. doi: 10.1111/cei.12393.

PMID:
24905474
[PubMed - in process]
5.

Targeted nanodrugs for cancer therapy: prospects and challenges.

Bottini M, Sacchetti C, Pietroiusti A, Bellucci S, Magrini A, Rosato N, Bottini N.

J Nanosci Nanotechnol. 2014 Jan;14(1):98-114. Review.

PMID:
24730253
[PubMed - indexed for MEDLINE]
6.

Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells.

Wu DJ, Zhou W, Enouz S, OrrĂº V, Stanford SM, Maine CJ, Rapini N, Sawatzke K, Engel I, Fiorillo E, Sherman LA, Kronenberg M, Zehn D, Peterson E, Bottini N.

PLoS One. 2014 Feb 3;9(2):e86677. doi: 10.1371/journal.pone.0086677. eCollection 2014.

PMID:
24498279
[PubMed - in process]
Free PMC Article
7.

Covalent inhibition of the lymphoid tyrosine phosphatase.

Ahmed VF, Bottini N, Barrios AM.

ChemMedChem. 2014 Feb;9(2):296-9. doi: 10.1002/cmdc.201300404. Epub 2014 Jan 8.

PMID:
24403103
[PubMed - indexed for MEDLINE]
8.

Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease.

Bottini N, Peterson EJ.

Annu Rev Immunol. 2014;32:83-119. doi: 10.1146/annurev-immunol-032713-120249. Epub 2013 Dec 18.

PMID:
24364806
[PubMed - in process]
9.

Cellular biochemistry methods for investigating protein tyrosine phosphatases.

Stanford SM, Ahmed V, Barrios AM, Bottini N.

Antioxid Redox Signal. 2014 May 10;20(14):2160-78. doi: 10.1089/ars.2013.5731. Epub 2014 Feb 25.

PMID:
24294920
[PubMed - in process]
10.

Epigenetics in rheumatoid arthritis: a primer for rheumatologists.

Bottini N, Firestein GS.

Curr Rheumatol Rep. 2013 Nov;15(11):372. doi: 10.1007/s11926-013-0372-9. Review.

PMID:
24072602
[PubMed - indexed for MEDLINE]
11.

Substrate selection influences molecular recognition in a screen for lymphoid tyrosine phosphatase inhibitors.

Kulkarni RA, Vellore NA, Bliss MR, Stanford SM, Falk MD, Bottini N, Baron R, Barrios AM.

Chembiochem. 2013 Sep 2;14(13):1640-7. doi: 10.1002/cbic.201300273. Epub 2013 Aug 16.

PMID:
23956195
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

pCAP-based peptide substrates: the new tool in the box of tyrosine phosphatase assays.

Stanford SM, Krishnamurthy D, Kulkarni RA, Karver CE, Bruenger E, Walker LM, Ma CT, Chung TD, Sergienko E, Bottini N, Barrios AM.

Methods. 2014 Jan 15;65(2):165-74. doi: 10.1016/j.ymeth.2013.07.022. Epub 2013 Jul 22.

PMID:
23886911
[PubMed - in process]
13.

Thiuram disulfides as pseudo-irreversible inhibitors of lymphoid tyrosine phosphatase.

Kulkarni RA, Stanford SM, Vellore NA, Krishnamurthy D, Bliss MR, Baron R, Bottini N, Barrios AM.

ChemMedChem. 2013 Sep;8(9):1561-8. doi: 10.1002/cmdc.201300215. Epub 2013 Jul 19.

PMID:
23873737
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity.

Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH Jr, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ.

Immunity. 2013 Jul 25;39(1):111-22. doi: 10.1016/j.immuni.2013.06.013. Epub 2013 Jul 18.

PMID:
23871208
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.

He Y, Liu S, Menon A, Stanford S, Oppong E, Gunawan AM, Wu L, Wu DJ, Barrios AM, Bottini N, Cato AC, Zhang ZY.

J Med Chem. 2013 Jun 27;56(12):4990-5008. doi: 10.1021/jm400248c. Epub 2013 Jun 6.

PMID:
23713581
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

In vivo targeting of intratumor regulatory T cells using PEG-modified single-walled carbon nanotubes.

Sacchetti C, Rapini N, Magrini A, Cirelli E, Bellucci S, Mattei M, Rosato N, Bottini N, Bottini M.

Bioconjug Chem. 2013 Jun 19;24(6):852-8. doi: 10.1021/bc400070q. Epub 2013 May 22.

PMID:
23682992
[PubMed - indexed for MEDLINE]
17.

Surface polyethylene glycol conformation influences the protein corona of polyethylene glycol-modified single-walled carbon nanotubes: potential implications on biological performance.

Sacchetti C, Motamedchaboki K, Magrini A, Palmieri G, Mattei M, Bernardini S, Rosato N, Bottini N, Bottini M.

ACS Nano. 2013 Mar 26;7(3):1974-89. doi: 10.1021/nn400409h. Epub 2013 Feb 28.

PMID:
23413928
[PubMed - indexed for MEDLINE]
18.

Protein tyrosine phosphatase expression profile of rheumatoid arthritis fibroblast-like synoviocytes: a novel role of SH2 domain-containing phosphatase 2 as a modulator of invasion and survival.

Stanford SM, Maestre MF, Campbell AM, Bartok B, Kiosses WB, Boyle DL, Arnett HA, Mustelin T, Firestein GS, Bottini N.

Arthritis Rheum. 2013 May;65(5):1171-80. doi: 10.1002/art.37872.

PMID:
23335101
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Duality of fibroblast-like synoviocytes in RA: passive responders and imprinted aggressors.

Bottini N, Firestein GS.

Nat Rev Rheumatol. 2013 Jan;9(1):24-33. doi: 10.1038/nrrheum.2012.190. Epub 2012 Nov 13. Review.

PMID:
23147896
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45.

Stanford SM, Panchal RG, Walker LM, Wu DJ, Falk MD, Mitra S, Damle SS, Ruble D, Kaltcheva T, Zhang S, Zhang ZY, Bavari S, Barrios AM, Bottini N.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):13972-7. doi: 10.1073/pnas.1205028109. Epub 2012 Aug 13.

PMID:
22891353
[PubMed - indexed for MEDLINE]
Free PMC Article

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