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Items: 1 to 20 of 114


In vitro inhibition of Plasmodium falciparum early and late stage gametocyte viability by extracts from eight traditionally used South African plant species.

Moyo P, Botha ME, Nondaba S, Niemand J, Maharaj VJ, Eloff JN, Louw AI, Birkholtz L.

J Ethnopharmacol. 2016 Jun 5;185:235-42. doi: 10.1016/j.jep.2016.03.036. Epub 2016 Mar 16.


School-based human papillomavirus vaccination: An opportunity to increase knowledge about cervical cancer and improve uptake of screening.

Dreyer G, van der Merwe FH, Botha MH, Snyman LC, Constant D, Visser C, Harvey J.

S Afr Med J. 2015 Oct 9;105(11):912-6. doi: 10.7196/SAMJ.2015.v105i11.9814.


A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.

Le Manach C, Paquet T, Brunschwig C, Njoroge M, Han Z, Gonzàlez Cabrera D, Bashyam S, Dhinakaran R, Taylor D, Reader J, Botha M, Churchyard A, Lauterbach S, Coetzer TL, Birkholtz LM, Meister S, Winzeler EA, Waterson D, Witty MJ, Wittlin S, Jiménez-Díaz MB, Santos Martínez M, Ferrer S, Angulo-Barturen I, Street LJ, Chibale K.

J Med Chem. 2015 Nov 12;58(21):8713-22. doi: 10.1021/acs.jmedchem.5b01605. Epub 2015 Nov 2.


Cervical HPV natural history among young Western Cape, South African women: The randomized control EVRI Trial.

Sudenga SL, Torres BN, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, Engelbrecht S, Schim Van der Loeff MF, Van der Laan LE, Kipping S, Taylor D, Giuliano AR.

J Infect. 2016 Jan;72(1):60-9. doi: 10.1016/j.jinf.2015.10.001. Epub 2015 Oct 19.


Bcl-2 confers survival in cisplatin treated cervical cancer cells: circumventing cisplatin dose-dependent toxicity and resistance.

Leisching G, Loos B, Botha M, Engelbrecht AM.

J Transl Med. 2015 Oct 16;13:328. doi: 10.1186/s12967-015-0689-4.


HPV vaccine: Can we afford to hesitate?

South African HPV Advisory Board, Richter KL, Dreyer G, Lindeque BG, Botha MH.

S Afr Med J. 2014 Aug;104(8):522-3. No abstract available.


The Vaccine and Cervical Cancer Screen (VACCS) project: Linking cervical cancer screening to HPV vaccination in the South-West District of Tshwane, Gauteng, South Africa.

Snyman LC, Dreyer G, Botha MH, van der Merwe FH, Becker PJ.

S Afr Med J. 2015 Jan 6;105(2):115-20. doi: 10.7196/samj.8418.


The role of mTOR during cisplatin treatment in an in vitro and ex vivo model of cervical cancer.

Leisching GR, Loos B, Botha MH, Engelbrecht AM.

Toxicology. 2015 Sep 1;335:72-8. doi: 10.1016/j.tox.2015.07.010. Epub 2015 Jul 19.


The South African Food Sensitisation and Food Allergy population-based study of IgE-mediated food allergy: validity, safety, and acceptability.

Basera W, Botha M, Gray CL, Lunjani N, Watkins AS, Venter C, Allen KJ, Hlela C, Zar HJ, Levin ME.

Ann Allergy Asthma Immunol. 2015 Aug;115(2):113-9. doi: 10.1016/j.anai.2015.06.003. Epub 2015 Jun 20.


Nowhere to hide: interrogating different metabolic parameters of Plasmodium falciparum gametocytes in a transmission blocking drug discovery pipeline towards malaria elimination.

Reader J, Botha M, Theron A, Lauterbach SB, Rossouw C, Engelbrecht D, Wepener M, Smit A, Leroy D, Mancama D, Coetzer TL, Birkholtz LM.

Malar J. 2015 May 22;14:213. doi: 10.1186/s12936-015-0718-z.


A nontoxic concentration of cisplatin induces autophagy in cervical cancer: selective cancer cell death with autophagy inhibition as an adjuvant treatment.

Leisching G, Loos B, Botha M, Engelbrecht AM.

Int J Gynecol Cancer. 2015 Mar;25(3):380-8. doi: 10.1097/IGC.0000000000000365.


A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail.

Burger PB, Williams M, Sprenger J, Reeksting SB, Botha M, Müller IB, Joubert F, Birkholtz LM, Louw AI.

Malar J. 2015 Feb 5;14:54. doi: 10.1186/s12936-015-0572-z.


High HIV, HPV, and STI prevalence among young Western Cape, South African women: EVRI HIV prevention preparedness trial.

Giuliano AR, Botha MH, Zeier M, Abrahamsen ME, Glashoff RH, van der Laan LE, Papenfuss M, Engelbrecht S, Schim van der Loeff MF, Sudenga SL, Torres BN, Kipping S, Taylor D.

J Acquir Immune Defic Syndr. 2015 Feb 1;68(2):227-35. doi: 10.1097/QAI.0000000000000425. Erratum in: J Acquir Immune Defic Syndr. 2015 Oct 1;70(2):e72.


Combination antiretroviral therapy reduces the detection risk of cervical human papilloma virus infection in women living with HIV.

Zeier MD, Botha MH, Engelbrecht S, Machekano RN, Jacobs GB, Isaacs S, van Schalkwyk M, van der Merwe H, Mason D, Nachega JB.

AIDS. 2015 Jan 2;29(1):59-66. doi: 10.1097/QAD.0000000000000512.


Safewards: the empirical basis of the model and a critical appraisal.

Bowers L, Alexander J, Bilgin H, Botha M, Dack C, James K, Jarrett M, Jeffery D, Nijman H, Owiti JA, Papadopoulos C, Ross J, Wright S, Stewart D.

J Psychiatr Ment Health Nurs. 2014 May;21(4):354-64. doi: 10.1111/jpm.12085. Epub 2014 Jan 24.


Adrenaline and amiodarone dosages in resuscitation: rectifying misinformation.

Botha M, Wells M, Dickerson R, Wallis L, Stander M; ARREST Special Interest Group of EMSSA.

S Afr Med J. 2013 Sep 3;103(10):713-4. doi: 10.7196/samj.7347. Review.


The impact of voluntary exercise on relative telomere length in a rat model of developmental stress.

Botha M, Grace L, Bugarith K, Russell VA, Kidd M, Seedat S, Hemmings SM.

BMC Res Notes. 2012 Dec 27;5:697. doi: 10.1186/1756-0500-5-697.

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