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Results: 1 to 20 of 23

1.

6-Acetonyldihydrochelerythrine Is a Potent Inducer of Apoptosis in HCT116 and SW620 Colon Cancer Cells.

Mansoor TA, Borralho PM, Luo X, Mulhovo S, Rodrigues CM, Ferreira MJ.

J Nat Prod. 2014 Jul 28. [Epub ahead of print]

PMID:
25066282
[PubMed - as supplied by publisher]
2.

Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies.

Luís DV, Silva J, Tomaz AI, de Almeida RF, Larguinho M, Baptista PV, Martins LM, Silva TF, Borralho PM, Rodrigues CM, Rodrigues AS, Pombeiro AJ, Fernandes AR.

J Biol Inorg Chem. 2014 Aug;19(6):787-803. doi: 10.1007/s00775-014-1110-0. Epub 2014 Jan 31.

PMID:
24481501
[PubMed - in process]
3.

c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.

Ferreira DM, Afonso MB, Rodrigues PM, Simão AL, Pereira DM, Borralho PM, Rodrigues CM, Castro RE.

Mol Cell Biol. 2014 Mar;34(6):1100-20. doi: 10.1128/MCB.00420-13. Epub 2014 Jan 13.

PMID:
24421392
[PubMed - indexed for MEDLINE]
4.

Synthesis, G-Quadruplex Stabilisation, Docking Studies, and Effect on Cancer Cells of Indolo[3,2-b]quinolines with One, Two, or Three Basic Side Chains.

Lavrado J, Borralho PM, Ohnmacht SA, Castro RE, Rodrigues CM, Moreira R, Santos DJ, Neidle S, Paulo A.

ChemMedChem. 2013 Aug 19. doi: 10.1002/cmdc.201300288. [Epub ahead of print]

PMID:
23960016
[PubMed - as supplied by publisher]
5.

Monoterpene bisindole alkaloids, from the African medicinal plant Tabernaemontana elegans, induce apoptosis in HCT116 human colon carcinoma cells.

Mansoor TA, Borralho PM, Dewanjee S, Mulhovo S, Rodrigues CM, Ferreira MJ.

J Ethnopharmacol. 2013 Sep 16;149(2):463-70. doi: 10.1016/j.jep.2013.06.051. Epub 2013 Jul 17.

PMID:
23872252
[PubMed - indexed for MEDLINE]
6.

Biological characterization of the antiproliferative potential of Co(II) and Sn(IV) coordination compounds in human cancer cell lines: a comparative proteomic approach.

Silva A, Luís D, Santos S, Silva J, Mendo AS, Coito L, Silva TF, da Silva MF, Martins LM, Pombeiro AJ, Borralho PM, Rodrigues CM, Cabral MG, Videira PA, Monteiro C, Fernandes AR.

Drug Metabol Drug Interact. 2013;28(3):167-76. doi: 10.1515/dmdi-2013-0015.

PMID:
23800656
[PubMed - indexed for MEDLINE]
7.

Apoptosis inducing activity of benzophenanthridine-type alkaloids and 2-arylbenzofuran neolignans in HCT116 colon carcinoma cells.

Mansoor TA, Borralho PM, Luo X, Mulhovo S, Rodrigues CM, Ferreira MJ.

Phytomedicine. 2013 Jul 15;20(10):923-9. doi: 10.1016/j.phymed.2013.03.026. Epub 2013 Apr 30.

PMID:
23643093
[PubMed - indexed for MEDLINE]
8.

Efficient recovery of proteins from multiple source samples after TRIzol(®) or TRIzol(®)LS RNA extraction and long-term storage.

Simões AE, Pereira DM, Amaral JD, Nunes AF, Gomes SE, Rodrigues PM, Lo AC, D'Hooge R, Steer CJ, Thibodeau SN, Borralho PM, Rodrigues CM.

BMC Genomics. 2013 Mar 15;14:181. doi: 10.1186/1471-2164-14-181.

PMID:
23496794
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Delivering the promise of miRNA cancer therapeutics.

Pereira DM, Rodrigues PM, Borralho PM, Rodrigues CM.

Drug Discov Today. 2013 Mar;18(5-6):282-9. doi: 10.1016/j.drudis.2012.10.002. Epub 2012 Oct 11. Review.

PMID:
23064097
[PubMed - indexed for MEDLINE]
10.

Cobalt complexes bearing scorpionate ligands: synthesis, characterization, cytotoxicity and DNA cleavage.

Silva TF, Martins LM, Guedes da Silva MF, Fernandes AR, Silva A, Borralho PM, Santos S, Rodrigues CM, Pombeiro AJ.

Dalton Trans. 2012 Nov 7;41(41):12888-97. doi: 10.1039/c2dt11577h.

PMID:
22986733
[PubMed - indexed for MEDLINE]
11.

miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease.

Castro RE, Ferreira DM, Afonso MB, Borralho PM, Machado MV, Cortez-Pinto H, Rodrigues CM.

J Hepatol. 2013 Jan;58(1):119-25. doi: 10.1016/j.jhep.2012.08.008. Epub 2012 Aug 15.

PMID:
22902550
[PubMed - indexed for MEDLINE]
12.

miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation.

Borralho PM, Simões AE, Gomes SE, Lima RT, Carvalho T, Ferreira DM, Vasconcelos MH, Castro RE, Rodrigues CM.

PLoS One. 2011;6(8):e23787. doi: 10.1371/journal.pone.0023787. Epub 2011 Aug 25.

PMID:
21901135
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

miRNA expression in colon polyps provides evidence for a multihit model of colon cancer.

Oberg AL, French AJ, Sarver AL, Subramanian S, Morlan BW, Riska SM, Borralho PM, Cunningham JM, Boardman LA, Wang L, Smyrk TC, Asmann Y, Steer CJ, Thibodeau SN.

PLoS One. 2011;6(6):e20465. doi: 10.1371/journal.pone.0020465. Epub 2011 Jun 9.

PMID:
21694772
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid.

Castro RE, Ferreira DM, Zhang X, Borralho PM, Sarver AL, Zeng Y, Steer CJ, Kren BT, Rodrigues CM.

Am J Physiol Gastrointest Liver Physiol. 2010 Oct;299(4):G887-97. doi: 10.1152/ajpgi.00216.2010. Epub 2010 Aug 5.

PMID:
20689055
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states.

Sarver AL, French AJ, Borralho PM, Thayanithy V, Oberg AL, Silverstein KA, Morlan BW, Riska SM, Boardman LA, Cunningham JM, Subramanian S, Wang L, Smyrk TC, Rodrigues CM, Thibodeau SN, Steer CJ.

BMC Cancer. 2009 Nov 18;9:401. doi: 10.1186/1471-2407-9-401.

PMID:
19922656
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells.

Borralho PM, Kren BT, Castro RE, da Silva IB, Steer CJ, Rodrigues CM.

FEBS J. 2009 Nov;276(22):6689-700. doi: 10.1111/j.1742-4658.2009.07383.x. Epub 2009 Oct 16.

PMID:
19843160
[PubMed - indexed for MEDLINE]
17.

Evaluation of a new high-dimensional miRNA profiling platform.

Cunningham JM, Oberg AL, Borralho PM, Kren BT, French AJ, Wang L, Bot BM, Morlan BW, Silverstein KA, Staggs R, Zeng Y, Lamblin AF, Hilker CA, Fan JB, Steer CJ, Thibodeau SN.

BMC Med Genomics. 2009 Aug 27;2:57. doi: 10.1186/1755-8794-2-57.

PMID:
19712457
[PubMed]
Free PMC Article
18.

Colorectal cancer: can nutrients modulate NF-kappaB and apoptosis?

Ravasco P, Aranha MM, Borralho PM, Moreira da Silva IB, Correia L, Fernandes A, Rodrigues CM, Camilo M.

Clin Nutr. 2010 Feb;29(1):42-6. doi: 10.1016/j.clnu.2009.06.006. Epub 2009 Jul 1.

PMID:
19573959
[PubMed - indexed for MEDLINE]
19.

NF-kappaB and apoptosis in colorectal tumourigenesis.

Aranha MM, Borralho PM, Ravasco P, Moreira da Silva IB, Correia L, Fernandes A, Camilo ME, Rodrigues CM.

Eur J Clin Invest. 2007 May;37(5):416-24.

PMID:
17461988
[PubMed - indexed for MEDLINE]
20.

Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53.

Borralho PM, Moreira da Silva IB, Aranha MM, Albuquerque C, Nobre Leitão C, Steer CJ, Rodrigues CM.

Biochim Biophys Acta. 2007 Jan;1772(1):40-7. Epub 2006 Sep 16.

PMID:
17056233
[PubMed - indexed for MEDLINE]
Free Article

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