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Results: 1 to 20 of 104

1.

The RUNX1-PU.1 axis in the control of hematopoiesis.

Imperato MR, Cauchy P, Obier N, Bonifer C.

Int J Hematol. 2015 Mar 8. [Epub ahead of print]

PMID:
25749719
2.

Cytokine and proinflammatory gene expression in classical Hodgkin lymphoma: Its more than NF-κB!

Kreher S, Cauchy P, Bonifer C, Mathas S.

Cytokine. 2015 Mar;72(1):115-7. doi: 10.1016/j.cyto.2014.12.012. Epub 2015 Jan 10. No abstract available.

PMID:
25585876
3.

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.

Kreher S, Bouhlel MA, Cauchy P, Lamprecht B, Li S, Grau M, Hummel F, Köchert K, Anagnostopoulos I, Jöhrens K, Hummel M, Hiscott J, Wenzel SS, Lenz P, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4513-22. doi: 10.1073/pnas.1406985111. Epub 2014 Oct 6.

4.

Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Ptasinska A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O, Bonifer C.

Cell Rep. 2014 Sep 25;8(6):1974-88. doi: 10.1016/j.celrep.2014.08.024. Epub 2014 Sep 18.

5.

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.

Lie-A-Ling M, Marinopoulou E, Li Y, Patel R, Stefanska M, Bonifer C, Miller C, Kouskoff V, Lacaud G.

Blood. 2014 Sep 11;124(11):e11-20. doi: 10.1182/blood-2014-04-572958. Epub 2014 Jul 31.

PMID:
25082880
6.

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Gilmour J, Assi SA, Jaegle U, Kulu D, van de Werken H, Clarke D, Westhead DR, Philipsen S, Bonifer C.

Development. 2014 Jun;141(12):2391-401. doi: 10.1242/dev.106054. Epub 2014 May 21.

7.

Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.

Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG.

Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Erratum in: Cancer Cell. 2014 Feb 10;25(2):257. Diruscio, Annalisa [corrected to Di Ruscio, Annalisa].

8.

Delineating MEIS1 cis-regulatory elements active in hematopoietic cells.

Xiang P, Wei W, Lo C, Rosten P, Hou J, Hoodless PA, Bilenky M, Bonifer C, Cockerill PN, Kirkpatrick A, Gottgens B, Hirst M, Humphries KR.

Leukemia. 2014 Feb;28(2):433-6. doi: 10.1038/leu.2013.287. Epub 2013 Oct 7. No abstract available.

PMID:
24097337
9.

Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data.

Piper J, Elze MC, Cauchy P, Cockerill PN, Bonifer C, Ott S.

Nucleic Acids Res. 2013 Nov;41(21):e201. doi: 10.1093/nar/gkt850. Epub 2013 Sep 25. Erratum in: Nucleic Acids Res. 2014;42(17):11272.

10.

Chronic growth factor receptor signaling and lineage inappropriate gene expression in AML: the polycomb connection.

Ray D, Kwon SY, Ptasinska A, Bonifer C.

Cell Cycle. 2013 Jul 15;12(14):2159-60. No abstract available.

11.

Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression.

Ray D, Kwon SY, Tagoh H, Heidenreich O, Ptasinska A, Bonifer C.

Blood. 2013 Aug 1;122(5):759-69. doi: 10.1182/blood-2013-02-482497. Epub 2013 Apr 24.

12.

The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus.

Sauter KA, Bouhlel MA, O'Neal J, Sester DP, Tagoh H, Ingram RM, Pridans C, Bonifer C, Hume DA.

PLoS One. 2013;8(1):e54935. doi: 10.1371/journal.pone.0054935. Epub 2013 Jan 31.

13.

The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.

Ladopoulos V, Hofemeister H, Hoogenkamp M, Riggs AD, Stewart AF, Bonifer C.

Mol Cell Biol. 2013 Apr;33(7):1383-93. doi: 10.1128/MCB.01721-12. Epub 2013 Jan 28.

14.

Why detailed model gene studies in higher eukaryotes are still necessary.

Bonifer C.

Immunology. 2013 Jun;139(2):158-60. doi: 10.1111/imm.12066. Review.

15.

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.

Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D, Assi SA, Lie-A-Ling M, Noailles L, Vijayabaskar MS, Wu M, Tenen DG, Westhead DR, Kouskoff V, Lacaud G, Göttgens B, Bonifer C.

EMBO J. 2012 Nov 14;31(22):4318-33. doi: 10.1038/emboj.2012.275. Epub 2012 Oct 12.

16.

The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers.

Baxter EW, Mirabella F, Bowers SR, James SR, Bonavita AM, Bertrand E, Strogantsev R, Hawwari A, Bert AG, Gonzalez de Arce A, West AG, Bonifer C, Cockerill PN.

J Immunol. 2012 Nov 1;189(9):4459-69. doi: 10.4049/jimmunol.1201915. Epub 2012 Sep 28.

17.

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.

Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, Vargel O, Wilson NK, Möröy T, Bonifer C, Göttgens B, Kouskoff V, Lacaud G.

Blood. 2012 Jul 12;120(2):314-22. doi: 10.1182/blood-2011-10-386094. Epub 2012 Jun 5.

18.

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C.

Leukemia. 2012 Aug;26(8):1829-41. doi: 10.1038/leu.2012.49. Epub 2012 Feb 20.

19.

RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.

Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG.

EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285.

20.

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F.

Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5.

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