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Results: 1 to 20 of 102

1.

Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphoma.

Kreher S, Bouhlel MA, Cauchy P, Lamprecht B, Li S, Grau M, Hummel F, Köchert K, Anagnostopoulos I, Jöhrens K, Hummel M, Hiscott J, Wenzel SS, Lenz P, Schneider M, Küppers R, Scheidereit C, Giefing M, Siebert R, Rajewsky K, Lenz G, Cockerill PN, Janz M, Dörken B, Bonifer C, Mathas S.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4513-22. doi: 10.1073/pnas.1406985111. Epub 2014 Oct 6.

PMID:
25288773
[PubMed - in process]
Free PMC Article
2.

Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.

Ptasinska A, Assi SA, Martinez-Soria N, Imperato MR, Piper J, Cauchy P, Pickin A, James SR, Hoogenkamp M, Williamson D, Wu M, Tenen DG, Ott S, Westhead DR, Cockerill PN, Heidenreich O, Bonifer C.

Cell Rep. 2014 Sep 25;8(6):1974-88. doi: 10.1016/j.celrep.2014.08.024. Epub 2014 Sep 18.

PMID:
25242324
[PubMed - in process]
Free Article
3.

RUNX1 positively regulates a cell adhesion and migration program in murine hemogenic endothelium prior to blood emergence.

Lie-A-Ling M, Marinopoulou E, Li Y, Patel R, Stefanska M, Bonifer C, Miller C, Kouskoff V, Lacaud G.

Blood. 2014 Sep 11;124(11):e11-20. doi: 10.1182/blood-2014-04-572958. Epub 2014 Jul 31.

PMID:
25082880
[PubMed - indexed for MEDLINE]
4.

A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.

Gilmour J, Assi SA, Jaegle U, Kulu D, van de Werken H, Clarke D, Westhead DR, Philipsen S, Bonifer C.

Development. 2014 Jun;141(12):2391-401. doi: 10.1242/dev.106054. Epub 2014 May 21.

PMID:
24850855
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia.

Zhang H, Alberich-Jorda M, Amabile G, Yang H, Staber PB, Di Ruscio A, Welner RS, Ebralidze A, Zhang J, Levantini E, Lefebvre V, Valk PJ, Delwel R, Hoogenkamp M, Nerlov C, Cammenga J, Saez B, Scadden DT, Bonifer C, Ye M, Tenen DG.

Cancer Cell. 2013 Nov 11;24(5):575-88. doi: 10.1016/j.ccr.2013.09.018. Epub 2013 Oct 31. Erratum in: Cancer Cell. 2014 Feb 10;25(2):257. Diruscio, Annalisa [corrected to Di Ruscio, Annalisa].

PMID:
24183681
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Delineating MEIS1 cis-regulatory elements active in hematopoietic cells.

Xiang P, Wei W, Lo C, Rosten P, Hou J, Hoodless PA, Bilenky M, Bonifer C, Cockerill PN, Kirkpatrick A, Gottgens B, Hirst M, Humphries KR.

Leukemia. 2014 Feb;28(2):433-6. doi: 10.1038/leu.2013.287. Epub 2013 Oct 7. No abstract available.

PMID:
24097337
[PubMed - indexed for MEDLINE]
7.

Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data.

Piper J, Elze MC, Cauchy P, Cockerill PN, Bonifer C, Ott S.

Nucleic Acids Res. 2013 Nov;41(21):e201. doi: 10.1093/nar/gkt850. Epub 2013 Sep 25.

PMID:
24071585
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Chronic growth factor receptor signaling and lineage inappropriate gene expression in AML: the polycomb connection.

Ray D, Kwon SY, Ptasinska A, Bonifer C.

Cell Cycle. 2013 Jul 15;12(14):2159-60. No abstract available.

PMID:
23803734
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Lineage-inappropriate PAX5 expression in t(8;21) acute myeloid leukemia requires signaling-mediated abrogation of polycomb repression.

Ray D, Kwon SY, Tagoh H, Heidenreich O, Ptasinska A, Bonifer C.

Blood. 2013 Aug 1;122(5):759-69. doi: 10.1182/blood-2013-02-482497. Epub 2013 Apr 24.

PMID:
23616623
[PubMed - indexed for MEDLINE]
Free Article
10.

The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus.

Sauter KA, Bouhlel MA, O'Neal J, Sester DP, Tagoh H, Ingram RM, Pridans C, Bonifer C, Hume DA.

PLoS One. 2013;8(1):e54935. doi: 10.1371/journal.pone.0054935. Epub 2013 Jan 31.

PMID:
23383005
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.

Ladopoulos V, Hofemeister H, Hoogenkamp M, Riggs AD, Stewart AF, Bonifer C.

Mol Cell Biol. 2013 Apr;33(7):1383-93. doi: 10.1128/MCB.01721-12. Epub 2013 Jan 28.

PMID:
23358417
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Why detailed model gene studies in higher eukaryotes are still necessary.

Bonifer C.

Immunology. 2013 Jun;139(2):158-60. doi: 10.1111/imm.12066. Review.

PMID:
23311893
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.

Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D, Assi SA, Lie-A-Ling M, Noailles L, Vijayabaskar MS, Wu M, Tenen DG, Westhead DR, Kouskoff V, Lacaud G, Göttgens B, Bonifer C.

EMBO J. 2012 Nov 14;31(22):4318-33. doi: 10.1038/emboj.2012.275. Epub 2012 Oct 12.

PMID:
23064151
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers.

Baxter EW, Mirabella F, Bowers SR, James SR, Bonavita AM, Bertrand E, Strogantsev R, Hawwari A, Bert AG, Gonzalez de Arce A, West AG, Bonifer C, Cockerill PN.

J Immunol. 2012 Nov 1;189(9):4459-69. doi: 10.4049/jimmunol.1201915. Epub 2012 Sep 28.

PMID:
23024272
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment.

Lancrin C, Mazan M, Stefanska M, Patel R, Lichtinger M, Costa G, Vargel O, Wilson NK, Möröy T, Bonifer C, Göttgens B, Kouskoff V, Lacaud G.

Blood. 2012 Jul 12;120(2):314-22. doi: 10.1182/blood-2011-10-386094. Epub 2012 Jun 5.

PMID:
22668850
[PubMed - indexed for MEDLINE]
Free Article
16.

Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.

Ptasinska A, Assi SA, Mannari D, James SR, Williamson D, Dunne J, Hoogenkamp M, Wu M, Care M, McNeill H, Cauchy P, Cullen M, Tooze RM, Tenen DG, Young BD, Cockerill PN, Westhead DR, Heidenreich O, Bonifer C.

Leukemia. 2012 Aug;26(8):1829-41. doi: 10.1038/leu.2012.49. Epub 2012 Feb 20.

PMID:
22343733
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element.

Levantini E, Lee S, Radomska HS, Hetherington CJ, Alberich-Jorda M, Amabile G, Zhang P, Gonzalez DA, Zhang J, Basseres DS, Wilson NK, Koschmieder S, Huang G, Zhang DE, Ebralidze AK, Bonifer C, Okuno Y, Gottgens B, Tenen DG.

EMBO J. 2011 Aug 26;30(19):4059-70. doi: 10.1038/emboj.2011.285.

PMID:
21873977
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Macrophage development from HSCs requires PU.1-coordinated microRNA expression.

Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F.

Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5.

PMID:
21730352
[PubMed - indexed for MEDLINE]
Free Article
19.

Chromatin mechanisms regulating gene expression in health and disease.

Bonifer C, Cockerill PN.

Adv Exp Med Biol. 2011;711:12-25. Review.

PMID:
21627039
[PubMed - indexed for MEDLINE]
20.

Differential regulation of sense and antisense promoter activity at the Csf1R locus in B cells by the transcription factor PAX5.

Ingram RM, Valeaux S, Wilson N, Bouhlel MA, Clarke D, Krüger I, Kulu D, Suske G, Philipsen S, Tagoh H, Bonifer C.

Exp Hematol. 2011 Jul;39(7):730-40.e1-2. doi: 10.1016/j.exphem.2011.04.004. Epub 2011 Apr 23.

PMID:
21549805
[PubMed - indexed for MEDLINE]

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