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Results: 1 to 20 of 67

1.

Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.

Pawlikowski JS, Brock C, Chen SC, Al-Olabi L, Nixon C, McGregor F, Paine S, Chanudet E, Lambie W, Holmes WM, Mullin JM, Richmond A, Wu H, Blyth K, King A, Kinsler VA, Adams PD.

J Invest Dermatol. 2015 Mar 27. doi: 10.1038/jid.2015.114. [Epub ahead of print]

PMID:
25815427
2.

Annexin A8 Identifies a Subpopulation of Transiently Quiescent c-Kit Positive Luminal Progenitor Cells of the Ductal Mammary Epithelium.

Iglesias JM, Cairney CJ, Ferrier RK, McDonald L, Soady K, Kendrick H, Pringle MA, Morgan RO, Martin F, Smalley MJ, Blyth K, Stein T.

PLoS One. 2015 Mar 24;10(3):e0119718. doi: 10.1371/journal.pone.0119718. eCollection 2015.

3.

Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.

Ichim G, Lopez J, Ahmed SU, Muthalagu N, Giampazolias E, Delgado ME, Haller M, Riley JS, Mason SM, Athineos D, Parsons MJ, van de Kooij B, Bouchier-Hayes L, Chalmers AJ, Rooswinkel RW, Oberst A, Blyth K, Rehm M, Murphy DJ, Tait SW.

Mol Cell. 2015 Mar 5;57(5):860-72. doi: 10.1016/j.molcel.2015.01.018. Epub 2015 Feb 19.

4.

Fumarate induces redox-dependent senescence by modifying glutathione metabolism.

Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, Johnson TI, Gaude E, King A, Leach JD, Edrada-Ebel R, Hedley A, Morrice NA, Kalna G, Blyth K, Ruppin E, Frezza C, Gottlieb E.

Nat Commun. 2015 Jan 23;6:6001. doi: 10.1038/ncomms7001.

5.

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress.

Schug ZT, Peck B, Jones DT, Zhang Q, Grosskurth S, Alam IS, Goodwin LM, Smethurst E, Mason S, Blyth K, McGarry L, James D, Shanks E, Kalna G, Saunders RE, Jiang M, Howell M, Lassailly F, Thin MZ, Spencer-Dene B, Stamp G, van den Broek NJ, Mackay G, Bulusu V, Kamphorst JJ, Tardito S, Strachan D, Harris AL, Aboagye EO, Critchlow SE, Wakelam MJ, Schulze A, Gottlieb E.

Cancer Cell. 2015 Jan 12;27(1):57-71. doi: 10.1016/j.ccell.2014.12.002.

6.

Speech and swallow rehabilitation following partial glossectomy: A systematic review.

Blyth KM, McCabe P, Madill C, Ballard KJ.

Int J Speech Lang Pathol. 2014 Dec 17:1-10. [Epub ahead of print]

PMID:
25515427
7.

HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia.

Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN, Anannya O, McBryan T, Manoharan I, van Tuyn J, Morrice N, Pchelintsev NA, Ivanov A, Brock C, Drotar ME, Nixon C, Clark W, Sansom OJ, Anderson KI, King A, Blyth K, Adams PD.

Genes Dev. 2014 Dec 15;28(24):2712-25. doi: 10.1101/gad.247528.114.

PMID:
25512559
8.

Inconsistent results or inconsistent methods? A plea for standardisation of biomarker sampling in mesothelioma studies.

Blyth KG.

Thorax. 2015 Apr;70(4):374. doi: 10.1136/thoraxjnl-2014-206464. Epub 2014 Dec 5. No abstract available.

PMID:
25480442
9.

Intrapleural tissue plasminogen activator and deoxyribonuclease for pleural infection. An effective and safe alternative to surgery.

Piccolo F, Pitman N, Bhatnagar R, Popowicz N, Smith NA, Brockway B, Nickels R, Burke AJ, Wong CA, McCartney R, Choo-Kang B, Blyth KG, Maskell NA, Lee YC.

Ann Am Thorac Soc. 2014 Nov;11(9):1419-25. doi: 10.1513/AnnalsATS.201407-329OC.

PMID:
25296241
10.

Cancers of the tongue and floor of mouth: five-year file audit within the acute phase.

Blyth KM, McCabe P, Heard R, Clark J, Madill C, Ballard KJ.

Am J Speech Lang Pathol. 2014 Nov;23(4):668-78. doi: 10.1044/2014_AJSLP-14-0003.

PMID:
25089517
11.

Expression of RUNX1 correlates with poor patient prognosis in triple negative breast cancer.

Ferrari N, Mohammed ZM, Nixon C, Mason SM, Mallon E, McMillan DC, Morris JS, Cameron ER, Edwards J, Blyth K.

PLoS One. 2014 Jun 26;9(6):e100759. doi: 10.1371/journal.pone.0100759. eCollection 2014.

12.

RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.

McDonald L, Ferrari N, Terry A, Bell M, Mohammed ZM, Orange C, Jenkins A, Muller WJ, Gusterson BA, Neil JC, Edwards J, Morris JS, Cameron ER, Blyth K.

Dis Model Mech. 2014 May;7(5):525-34. doi: 10.1242/dmm.015040. Epub 2014 Mar 13.

13.

Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.

Li A, Morton JP, Ma Y, Karim SA, Zhou Y, Faller WJ, Woodham EF, Morris HT, Stevenson RP, Juin A, Jamieson NB, MacKay CJ, Carter CR, Leung HY, Yamashiro S, Blyth K, Sansom OJ, Machesky LM.

Gastroenterology. 2014 May;146(5):1386-96.e1-17. doi: 10.1053/j.gastro.2014.01.046. Epub 2014 Jan 23.

14.

Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.

Zheng L, Mackenzie ED, Karim SA, Hedley A, Blyth K, Kalna G, Watson DG, Szlosarek P, Frezza C, Gottlieb E.

Cancer Metab. 2013 Mar 21;1(1):12. doi: 10.1186/2049-3002-1-12.

15.

iRFP is a sensitive marker for cell number and tumor growth in high-throughput systems.

Hock AK, Lee P, Maddocks OD, Mason SM, Blyth K, Vousden KH.

Cell Cycle. 2014;13(2):220-6. doi: 10.4161/cc.26985. Epub 2013 Oct 31.

16.

Changes in right ventricular function measured by cardiac magnetic resonance imaging in patients receiving pulmonary arterial hypertension-targeted therapy: the EURO-MR study.

Peacock AJ, Crawley S, McLure L, Blyth K, Vizza CD, Poscia R, Francone M, Iacucci I, Olschewski H, Kovacs G, Vonk Noordegraaf A, Marcus JT, van de Veerdonk MC, Oosterveer FP.

Circ Cardiovasc Imaging. 2014 Jan;7(1):107-14. doi: 10.1161/CIRCIMAGING.113.000629. Epub 2013 Oct 30.

17.

Wnt signaling potentiates nevogenesis.

Pawlikowski JS, McBryan T, van Tuyn J, Drotar ME, Hewitt RN, Maier AB, King A, Blyth K, Wu H, Adams PD.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16009-14. doi: 10.1073/pnas.1303491110. Epub 2013 Sep 16.

18.

TIGAR is required for efficient intestinal regeneration and tumorigenesis.

Cheung EC, Athineos D, Lee P, Ridgway RA, Lambie W, Nixon C, Strathdee D, Blyth K, Sansom OJ, Vousden KH.

Dev Cell. 2013 Jun 10;25(5):463-77. doi: 10.1016/j.devcel.2013.05.001. Epub 2013 May 30.

19.

A new custom moldable external neck brace (ENB 2.0) to improve hands-free speech in laryngectomized patients.

Dirven R, Clark JR, Wismans JG, McGuiness J, Palme CE, Blyth K, Baxter C, Stone DB, Marres HA.

Laryngoscope. 2013 Sep;123(9):2209-15. doi: 10.1002/lary.24044. Epub 2013 Mar 11.

PMID:
23483541
20.

Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells.

Maddocks OD, Berkers CR, Mason SM, Zheng L, Blyth K, Gottlieb E, Vousden KH.

Nature. 2013 Jan 24;493(7433):542-6. doi: 10.1038/nature11743. Epub 2012 Dec 16.

PMID:
23242140
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